Antibody-supervised deep learning for quantification of tumor-infiltrating immune cells in hematoxylin and eosin stained breast cancer samples

por Turkki, Riku, Linder, Nina, Kovanen, Panu E., Pellinen, Teijo, Lundin, Johan
Publicado 2016

Erythroid Progenitor Cells Expanded from Peripheral Blood without Mobilization or Preselection: Molecular Characteristics and Functional Competence

por Filippone, Claudia, Franssila, Rauli, Kumar, Arun, Saikko, Leena, Kovanen, Panu E., Söderlund-Venermo, Maria, Hedman, Klaus
Publicado 2010

The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis

por Lahtela, Jenni, Pradhan, Barun, Närhi, Katja, Hemmes, Annabrita, Särkioja, Merja, Kovanen, Panu E., Brown, Arthur, Verschuren, Emmy W.
Publicado 2015

Deep learning based tissue analysis predicts outcome in colorectal cancer

por Bychkov, Dmitrii, Linder, Nina, Turkki, Riku, Nordling, Stig, Kovanen, Panu E., Verrill, Clare, Walliander, Margarita, Lundin, Mikael, Haglund, Caj, Lundin, Johan
Publicado 2018

Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

por Hohtari, Helena, Brück, Oscar, Blom, Sami, Turkki, Riku, Sinisalo, Marjatta, Kovanen, Panu E., Kallioniemi, Olli, Pellinen, Teijo, Porkka, Kimmo, Mustjoki, Satu
Publicado 2019

Breast cancer outcome prediction with tumour tissue images and machine learning

por Turkki, Riku, Byckhov, Dmitrii, Lundin, Mikael, Isola, Jorma, Nordling, Stig, Kovanen, Panu E., Verrill, Clare, von Smitten, Karl, Joensuu, Heikki, Lundin, Johan, Linder, Nina
Publicado 2019

STAT3 Mutation Is Associated with STAT3 Activation in CD30(+) ALK(−) ALCL

por Andersson, Emma I., Brück, Oscar, Braun, Till, Mannisto, Susanna, Saikko, Leena, Lagström, Sonja, Ellonen, Pekka, Leppä, Sirpa, Herling, Marco, Kovanen, Panu E., Mustjoki, Satu
Publicado 2020

Spatial immunoprofiling of the intratumoral and peritumoral tissue of renal cell carcinoma patients

por Brück, Oscar, Lee, Moon Hee, Turkki, Riku, Uski, Ilona, Penttilä, Patrick, Paavolainen, Lassi, Kovanen, Panu, Järvinen, Petrus, Bono, Petri, Pellinen, Teijo, Mustjoki, Satu, Kreutzman, Anna
Publicado 2021

Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia

por Savola, Paula, Brück, Oscar, Olson, Thomas, Kelkka, Tiina, Kauppi, Markku J., Kovanen, Panu E., Kytölä, Soili, Sokka-Isler, Tuulikki, Loughran, Thomas P., Leirisalo-Repo, Marjatta, Mustjoki, Satu
Publicado 2018

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2

por Vakkilainen, Svetlana, Skoog, Tiina, Einarsdottir, Elisabet, Middleton, Anna, Pekkinen, Minna, Öhman, Tiina, Katayama, Shintaro, Krjutškov, Kaarel, Kovanen, Panu E., Varjosalo, Markku, Lindqvist, Arne, Kere, Juha, Mäkitie, Outi
Publicado 2019

Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas

por Leivonen, Suvi-Katri, Friman, Terhi, Autio, Matias, Vaittinen, Samuli, Jensen, Andreas Wind, d’Amore, Francesco, Hamilton-Dutoit, Stephen Jacques, Holte, Harald, Beiske, Klaus, Kovanen, Panu E., Räty, Riikka, Leppä, Sirpa
Publicado 2023

Stat5 Synergizes with T Cell Receptor/Antigen Stimulation in the Development of Lymphoblastic Lymphoma

por Kelly, John A., Spolski, Rosanne, Kovanen, Panu E., Suzuki, Takeshi, Bollenbacher, Julie, Pise-Masison, Cynthia A., Radonovich, Michael F., Lee, Stephen, Jenkins, Nancy A., Copeland, Neal G., Morse, Herbert C., Leonard, Warren J.
Publicado 2003

Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function

por Zeng, Rong, Spolski, Rosanne, Finkelstein, Steven E., Oh, SangKon, Kovanen, Panu E., Hinrichs, Christian S., Pise-Masison, Cynthia A., Radonovich, Michael F., Brady, John N., Restifo, Nicholas P., Berzofsky, Jay A., Leonard, Warren J.
Publicado 2005

Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease

por Keskitalo, Salla, Haapaniemi, Emma M., Glumoff, Virpi, Liu, Xiaonan, Lehtinen, Ville, Fogarty, Christopher, Rajala, Hanna, Chiang, Samuel C., Mustjoki, Satu, Kovanen, Panu, Lohi, Jouko, Bryceson, Yenan T., Seppänen, Mikko, Kere, Juha, Heiskanen, Kaarina, Varjosalo, Markku
Publicado 2019

Somatic mutations and T-cell clonality in patients with immunodeficiency

por Savola, Paula, Martelius, Timi, Kankainen, Matti, Huuhtanen, Jani, Lundgren, Sofie, Koski, Yrjö, Eldfors, Samuli, Kelkka, Tiina, Keränen, Mikko A.I., Ellonen, Pekka, Kovanen, Panu E., Kytölä, Soili, Saarela, Janna, Lähdesmäki, Harri, Seppänen, Mikko R.J., Mustjoki, Satu
Publicado 2019

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

por Dufva, Olli, Kankainen, Matti, Kelkka, Tiina, Sekiguchi, Nodoka, Awad, Shady Adnan, Eldfors, Samuli, Yadav, Bhagwan, Kuusanmäki, Heikki, Malani, Disha, Andersson, Emma I, Pietarinen, Paavo, Saikko, Leena, Kovanen, Panu E., Ojala, Teija, Lee, Dean A., Loughran, Thomas P., Nakazawa, Hideyuki, Suzumiya, Junji, Suzuki, Ritsuro, Ko, Young Hyeh, Kim, Won Seog, Chuang, Shih-Sung, Aittokallio, Tero, Chan, Wing C., Ohshima, Koichi, Ishida, Fumihiro, Mustjoki, Satu
Publicado 2018

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

por Haikala, Heidi M., Anttila, Johanna M., Marques, Elsa, Raatikainen, Tiina, Ilander, Mette, Hakanen, Henna, Ala-Hongisto, Hanna, Savelius, Mariel, Balboa, Diego, Von Eyss, Bjoern, Eskelinen, Vilja, Munne, Pauliina, Nieminen, Anni I., Otonkoski, Timo, Schüler, Julia, Laajala, Teemu D., Aittokallio, Tero, Sihto, Harri, Mattson, Johanna, Heikkilä, Päivi, Leidenius, Marjut, Joensuu, Heikki, Mustjoki, Satu, Kovanen, Panu, Eilers, Martin, Leverson, Joel D., Klefström, Juha
Publicado 2019

Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

por Haikala, Heidi M., Anttila, Johanna M., Marques, Elsa, Raatikainen, Tiina, Ilander, Mette, Hakanen, Henna, Ala-Hongisto, Hanna, Savelius, Mariel, Balboa, Diego, Von Eyss, Bjoern, Eskelinen, Vilja, Munne, Pauliina, Nieminen, Anni I., Otonkoski, Timo, Schüler, Julia, Laajala, Teemu D., Aittokallio, Tero, Sihto, Harri, Mattson, Johanna, Heikkilä, Päivi, Leidenius, Marjut, Joensuu, Heikki, Mustjoki, Satu, Kovanen, Panu, Eilers, Martin, Leverson, Joel D., Klefström, Juha
Publicado 2019

Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer

por Munne, Pauliina M., Martikainen, Lahja, Räty, Iiris, Bertula, Kia, Nonappa, Ruuska, Janika, Ala-Hongisto, Hanna, Peura, Aino, Hollmann, Babette, Euro, Lilya, Yavuz, Kerim, Patrikainen, Linda, Salmela, Maria, Pokki, Juho, Kivento, Mikko, Väänänen, Juho, Suomi, Tomi, Nevalaita, Liina, Mutka, Minna, Kovanen, Panu, Leidenius, Marjut, Meretoja, Tuomo, Hukkinen, Katja, Monni, Outi, Pouwels, Jeroen, Sahu, Biswajyoti, Mattson, Johanna, Joensuu, Heikki, Heikkilä, Päivi, Elo, Laura L., Metcalfe, Ciara, Junttila, Melissa R., Ikkala, Olli, Klefström, Juha
Publicado 2021

Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2

por Moffitt, Andrea B., Ondrejka, Sarah L., McKinney, Matthew, Rempel, Rachel E., Goodlad, John R., Teh, Chun Huat, Leppa, Sirpa, Mannisto, Susanna, Kovanen, Panu E., Tse, Eric, Au-Yeung, Rex K.H., Kwong, Yok-Lam, Srivastava, Gopesh, Iqbal, Javeed, Yu, Jiayu, Naresh, Kikkeri, Villa, Diego, Gascoyne, Randy D., Said, Jonathan, Czader, Magdalena B., Chadburn, Amy, Richards, Kristy L., Rajagopalan, Deepthi, Davis, Nicholas S., Smith, Eileen C., Palus, Brooke C., Tzeng, Tiffany J., Healy, Jane A., Lugar, Patricia L., Datta, Jyotishka, Love, Cassandra, Levy, Shawn, Dunson, David B., Zhuang, Yuan, Hsi, Eric D., Dave, Sandeep S.
Publicado 2017