Prognostic impact of Ikaros expression in lenalidomide-treated multiple myeloma

por Krönke, Jan, Knop, Stefan, Langer, Christian
Publicado 2017

Lenalidomide induces degradation of IKZF1 and IKZF3

por Krönke, Jan, Hurst, Slater N, Ebert, Benjamin L
Publicado 2014

Ubiquitination and Ubiquitin-Like Modifications in Multiple Myeloma: Biology and Therapy

por Wirth, Matthias, Schick, Markus, Keller, Ulrich, Krönke, Jan
Publicado 2020

Relapse of NPM1-Mutated AML with Extramedullary Manifestation 17 Years after Allogeneic Hematopoietic Stem Cell Transplantation

por Braune, Jan, Rieger, Kathrin, Blau, Olga, Keller, Ulrich, Bullinger, Lars, Krönke, Jan
Publicado 2022

Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia

por Hegazy, Ahmed N., Krönke, Jan, Angermair, Stefan, Schwartz, Stefan, Weidinger, Carl, Keller, Ulrich, Treskatsch, Sascha, Siegmund, Britta, Schneider, Thomas
Publicado 2022

Volasertib as a monotherapy or in combination with azacitidine in patients with myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia: summary of thr...

por Platzbecker, Uwe, Chromik, Joerg, Krönke, Jan, Handa, Hiroshi, Strickland, Stephen, Miyazaki, Yasushi, Wermke, Martin, Sakamoto, Wataru, Tachibana, Yoshifumi, Taube, Tillmann, Germing, Ulrich
Publicado 2022

Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins

por Ng, Yuen Lam Dora, Bricelj, Aleša, Jansen, Jacqueline A., Murgai, Arunima, Peter, Kirsten, Donovan, Katherine A., Gütschow, Michael, Krönke, Jan, Steinebach, Christian, Sosič, Izidor
Publicado 2023

Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design

por Kuchta, Robert, Heim, Christopher, Herrmann, Alexander, Maiwald, Samuel, Ng, Yuen Lam Dora, Sosič, Izidor, Keuler, Tim, Krönke, Jan, Gütschow, Michael, Hartmann, Marcus D., Steinebach, Christian
Publicado 2023

Genotype and Intensive Pretreatment Influence Outcome of Acute Myeloid Leukemia Patients Treated With Venetoclax in Combination With Hypomethylating Agents or Low-dose Cytarabine:...

por Braitsch, Krischan, Schmalbrock, Laura K., Jung, Paul, Bumeder, Irmgard, Kiewe, Philipp, Hecker, Judith S., Verbeek, Mareike, Westermann, Jörg, Bullinger, Lars, Keller, Ulrich, Bassermann, Florian, Krönke, Jan, Götze, Katharina S., Rieger, Kathrin
Publicado 2022

P829: GENOMIC PROFILING IN CFDNA COMPLEMENTS MOLECULAR DIAGNOSIS IN PATIENTS WITH MULTIPLE MYELOMA

por Schilhabel, Anke, Khouja, Mouhamad, Stewart, Peter, Strifler, Susanne, Stuebig, Thomas, Kull, Miriam, Baldus, Claudia, Pott, Christiane, Gonzalez de Castro, David, Engelhardt, Monika, Krönke, Jan, Einsele, Hermann, Knop, Stefan, Brüggemann, Monika
Publicado 2023

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia

por Hirsch, Susanne, Blätte, Tamara J., Grasedieck, Sarah, Cocciardi, Sibylle, Rouhi, Arefeh, Jongen-Lavrencic, Mojca, Paschka, Peter, Krönke, Jan, Gaidzik, Verena I., Döhner, Hartmut, Schlenk, Richard F., Kuchenbauer, Florian, Döhner, Konstanze, Dolnik, Anna, Bullinger, Lars
Publicado 2017

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)

por Meyer, Tatjana, Jahn, Nikolaus, Lindner, Stefanie, Röhner, Linda, Dolnik, Anna, Weber, Daniela, Scheffold, Annika, Köpff, Simon, Paschka, Peter, Gaidzik, Verena I., Heckl, Dirk, Wiese, Sebastian, Ebert, Benjamin L., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze, Krönke, Jan
Publicado 2019

The OTUD6B‐LIN28B‐MYC axis determines the proliferative state in multiple myeloma

por Paulmann, Carmen, Spallek, Ria, Karpiuk, Oleksandra, Heider, Michael, Schäffer, Isabell, Zecha, Jana, Klaeger, Susan, Walzik, Michaela, Öllinger, Rupert, Engleitner, Thomas, Wirth, Matthias, Keller, Ulrich, Krönke, Jan, Rudelius, Martina, Kossatz, Susanne, Rad, Roland, Kuster, Bernhard, Bassermann, Florian
Publicado 2022

Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders

por Steinebach, Christian, Ng, Yuen Lam Dora, Sosič, Izidor, Lee, Chih-Shia, Chen, Sirui, Lindner, Stefanie, Vu, Lan Phuong, Bricelj, Aleša, Haschemi, Reza, Monschke, Marius, Steinwarz, Elisabeth, Wagner, Karl G., Bendas, Gerd, Luo, Ji, Gütschow, Michael, Krönke, Jan
Publicado 2020

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma

por Ng, Yuen Lam Dora, Ramberger, Evelyn, Bohl, Stephan R., Dolnik, Anna, Steinebach, Christian, Conrad, Theresia, Müller, Sina, Popp, Oliver, Kull, Miriam, Haji, Mohamed, Gütschow, Michael, Döhner, Hartmut, Walther, Wolfgang, Keller, Ulrich, Bullinger, Lars, Mertins, Philipp, Krönke, Jan
Publicado 2022

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

por Steinebach, Christian, Bricelj, Aleša, Murgai, Arunima, Sosič, Izidor, Bischof, Luca, Ng, Yuen Lam Dora, Heim, Christopher, Maiwald, Samuel, Proj, Matic, Voget, Rabea, Feller, Felix, Košmrlj, Janez, Sapozhnikova, Valeriia, Schmidt, Annika, Zuleeg, Maximilian Rudolf, Lemnitzer, Patricia, Mertins, Philipp, Hansen, Finn K., Gütschow, Michael, Krönke, Jan, Hartmann, Marcus D.
Publicado 2023

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation

por Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Teleanu, Veronica, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Weber, Daniela, Sträng, Eric, Kestler, Hans A., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze
Publicado 2019

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

por Krönke, Jan, Fink, Emma C., Hollenbach, Paul W., MacBeth, Kyle J., Hurst, Slater N., Udeshi, Namrata D., Chamberlain, Philip P., Mani, D.R., Man, Hon Wah, Gandhi, Anita K., Svinkina, Tanya, Schneider, Rebekka K., McConkey, Marie, Järås, Marcus, Griffiths, Elizabeth, Wetzler, Meir, Bullinger, Lars, Cathers, Brian E., Carr, Steven A., Chopra, Rajesh, Ebert, Benjamin L.
Publicado 2015

SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma

por Heynen, Guus J. J. E., Baumgartner, Francis, Heider, Michael, Patra, Upayan, Holz, Maximilian, Braune, Jan, Kaiser, Melanie, Schäffer, Isabell, Bamopoulos, Stefanos A., Ramberger, Evelyn, Murgai, Arunima, Ng, Yuen Lam Dora, Demel, Uta Margareta, Laue, Dominik, Liebig, Sven, Krüger, Josefine, Janz, Martin, Nogai, Axel, Schick, Markus, Mertins, Philipp, Müller, Stefan, Bassermann, Florian, Krönke, Jan, Keller, Ulrich, Wirth, Matthias
Publicado 2022

S189: PROTEOGENOMIC LANDSCAPE OF MULTIPLE MYELOMA

por Ramberger, Evelyn, Dolnik, Anna, Ng, Yuen Lam Dora, Ziehm, Matthias, Popp, Oliver, Sträng, Eric, Kull, Miriam, Sapozhnikova, Valeriia, Grünschläger, Florian, Benary, Manuela, Müller, Sina, Gao, Xiang, Murgai, Arunima, Haji, Mohamed, Schmidt, Annika, Lutz, Raphael, Nogai, Axel, Braune, Jan, Laue, Dominik, Langer, Christian, Khandanpour, Cyrus, Bassermann, Florain, Döhner, Hartmut, Engelhardt, Monika, Straka, Christian, Hundemer, Michael, Haas, Simon, Beule, Dieter, Keller, Ulrich, Einsele, Hermann, Bullinger, Lars, Knop, Stefan, Mertins, Philipp, Krönke, Jan
Publicado 2023