Heme Oxygenase Isoforms Differ in Their Subcellular Trafficking during Hypoxia and Are Differentially Modulated by Cytochrome P450 Reductase

por Linnenbaum, Monika, Busker, Mareike, Kraehling, Jan R., Behrends, Soenke
Publicado 2012

The 10th International Conference on cGMP 2022: recent trends in cGMP research and development—meeting report

por Friebe, Andreas, Kraehling, Jan R., Russwurm, Michael, Sandner, Peter, Schmidtko, Achim
Publicado 2023

The Impact of the Nitric Oxide (NO)/Soluble Guanylyl Cyclase (sGC) Signaling Cascade on Kidney Health and Disease: A Preclinical Perspective

por Krishnan, Shalini M., Kraehling, Jan R., Eitner, Frank, Bénardeau, Agnès, Sandner, Peter
Publicado 2018

The Amino-Terminus of Nitric Oxide Sensitive Guanylyl Cyclase α(1) Does Not Affect Dimerization but Influences Subcellular Localization

por Kraehling, Jan R., Busker, Mareike, Haase, Tobias, Haase, Nadine, Koglin, Markus, Linnenbaum, Monika, Behrends, Soenke
Publicado 2011

BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells

por Tao, Bo, Kraehling, Jan R., Ghaffari, Siavash, Ramirez, Cristina M., Lee, Sungwoon, Fowler, Joseph W., Lee, Warren L., Fernandez-Hernando, Carlos, Eichmann, Anne, Sessa, William C.
Publicado 2021

Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney

por Stehle, Daniel, Xu, Min Ze, Schomber, Tibor, Hahn, Michael G., Schweda, Frank, Feil, Susanne, Kraehling, Jan R., Eitner, Frank, Patzak, Andreas, Sandner, Peter, Feil, Robert, Bénardeau, Agnès
Publicado 2021

Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency

por Protack, Clinton D., Foster, Trenton R., Hashimoto, Takuya, Yamamoto, Kota, Lee, Monica Y., Kraehling, Jan R., Bai, Hualong, Hu, Haidi, Isaji, Toshihiko, Santana, Jeans M., Wang, Mo, Sessa, William C., Dardik, Alan
Publicado 2017

Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease

por Bénardeau, Agnès, Kahnert, Antje, Schomber, Tibor, Meyer, Jutta, Pavkovic, Mira, Kretschmer, Axel, Lawrenz, Bettina, Hartmann, Elke, Mathar, Ilka, Hueser, Joerg, Kraehling, Jan R., Eitner, Frank, Hahn, Michael G., Stasch, Johannes-Peter, Sandner, Peter
Publicado 2021

The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats

por Kraehling, Jan R., Benardeau, Agnes, Schomber, Tibor, Popp, Laura, Vienenkoetter, Julia, Ellinger-Ziegelbauer, Heidrun, Pavkovic, Mira, Hartmann, Elke, Siudak, Krystyna, Freyberger, Alexius, Hagelschuer, Ina, Mathar, Ilka, Hueser, Joerg, Hahn, Michael G., Geiss, Volker, Eitner, Frank, Sandner, Peter
Publicado 2023

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia

por Ola, Roxana, Dubrac, Alexandre, Han, Jinah, Zhang, Feng, Fang, Jennifer S., Larrivée, Bruno, Lee, Monica, Urarte, Ana A., Kraehling, Jan R., Genet, Gael, Hirschi, Karen K., Sessa, William C., Canals, Francesc V., Graupera, Mariona, Yan, Minhong, Young, Lawrence H., Oh, Paul S., Eichmann, Anne
Publicado 2016

Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells

por Kraehling, Jan R., Chidlow, John H., Rajagopal, Chitra, Sugiyama, Michael G., Fowler, Joseph W., Lee, Monica Y., Zhang, Xinbo, Ramírez, Cristina M., Park, Eon Joo, Tao, Bo, Chen, Keyang, Kuruvilla, Leena, Larriveé, Bruno, Folta-Stogniew, Ewa, Ola, Roxana, Rotllan, Noemi, Zhou, Wenping, Nagle, Michael W., Herz, Joachim, Williams, Kevin Jon, Eichmann, Anne, Lee, Warren L., Fernández-Hernando, Carlos, Sessa, William C.
Publicado 2016