Genetic basis and molecular profiling in myeloproliferative neoplasms

por Luque Paz, Damien, Kralovics, Robert, Skoda, Radek C.
Publicado 2023

Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms

por Jäger, Roland, Harutyunyan, Ashot S, Rumi, Elisa, Pietra, Daniela, Berg, Tiina, Olcaydu, Damla, Houlston, Richard S, Cazzola, Mario, Kralovics, Robert
Publicado 2014

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line

por Essletzbichler, Patrick, Konopka, Tomasz, Santoro, Federica, Chen, Doris, Gapp, Bianca V., Kralovics, Robert, Brummelkamp, Thijn R., Nijman, Sebastian M.B., Bürckstümmer, Tilmann
Publicado 2014

Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans

por Kornienko, Aleksandra E., Dotter, Christoph P., Guenzl, Philipp M., Gisslinger, Heinz, Gisslinger, Bettina, Cleary, Ciara, Kralovics, Robert, Pauler, Florian M., Barlow, Denise P.
Publicado 2016

High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells

por Jia, Ruochen, Kutzner, Leon, Koren, Anna, Runggatscher, Kathrin, Májek, Peter, Müller, André C., Schuster, Michael, Bock, Christoph, Loizou, Joanna I., Kubicek, Stefan, Kralovics, Robert
Publicado 2021

Overexpression of primary microRNA 221/222 in acute myeloid leukemia

por Rommer, Anna, Steinleitner, Katarina, Hackl, Hubert, Schneckenleithner, Christine, Engelmann, Maria, Scheideler, Marcel, Vlatkovic, Irena, Kralovics, Robert, Cerny-Reiterer, Sabine, Valent, Peter, Sill, Heinz, Wieser, Rotraud
Publicado 2013

Myelomonocytic Skewing In Vitro Discriminates Subgroups of Patients with Myelofibrosis with A Different Phenotype, A Different Mutational Profile and Different Prognosis

por Geissler, Klaus, Gisslinger, Bettina, Jäger, Eva, Jäger, Roland, Schiefer, Ana-Iris, Bogner, Edith, Fuchs, Elisabeth, Schischlik, Fiorella, Alpar, Donat, Simonitsch-Klupp, Ingrid, Kralovics, Robert, Gisslinger, Heinz
Publicado 2020

An RNA-Seq Strategy to Detect the Complete Coding and Non-Coding Transcriptome Including Full-Length Imprinted Macro ncRNAs

por Huang, Ru, Jaritz, Markus, Guenzl, Philipp, Vlatkovic, Irena, Sommer, Andreas, Tamir, Ido M., Marks, Hendrik, Klampfl, Thorsten, Kralovics, Robert, Stunnenberg, Hendrik G., Barlow, Denise P., Pauler, Florian M.
Publicado 2011

Functional Dissection of the TBK1 Molecular Network

por Goncalves, Adriana, Bürckstümmer, Tilmann, Dixit, Evelyn, Scheicher, Ruth, Górna, Maria W., Karayel, Evren, Sugar, Cristina, Stukalov, Alexey, Berg, Tiina, Kralovics, Robert, Planyavsky, Melanie, Bennett, Keiryn L., Colinge, Jacques, Superti-Furga, Giulio
Publicado 2011

Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo

por Verger, Emmanuelle, Soret-Dulphy, Juliette, Maslah, Nabih, Roy, Lydia, Rey, Jerome, Ghrieb, Zineb, Kralovics, Robert, Gisslinger, Heinz, Grohmann-Izay, Barbara, Klade, Christoph, Chomienne, Christine, Giraudier, Stéphane, Cassinat, Bruno, Kiladjian, Jean-Jacques
Publicado 2018

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

por Shimizu, Takafumi, Kubovcakova, Lucia, Nienhold, Ronny, Zmajkovic, Jakub, Meyer, Sara C., Hao-Shen, Hui, Geier, Florian, Dirnhofer, Stephan, Guglielmelli, Paola, Vannucchi, Alessandro M., Feenstra, Jelena D. Milosevic, Kralovics, Robert, Orkin, Stuart H., Skoda, Radek C.
Publicado 2016

P1034: FROM SNAPSHOT TO CONTINUUM: CUMULATIVE TIME IN RESPONSE AS AN EMERGING PROXY FOR THROMBOTIC RISK IN POLYCYTHEMIA VERA

por Gisslinger, Heinz, Klade, Christoph, Georgiev, Pencho, Krochmalczyk, Dorota, Gercheva-Kyuchukova, Liana, Egyed, Miklos, Dulicek, Petr, Illes, Arpad, Pylypenko, Halyna, Sivcheva, Lylia, Mayer, Jiří, Yablokova, Vera, Krejcy, Kurt, Empson, Victoria, Hasselbalch, Hans C., Kralovics, Robert, Kiladjian, Jean-Jacques
Publicado 2023

Event-free survival in patients with polycythemia vera treated with ropeginterferon alfa-2b versus best available treatment

por Gisslinger, Heinz, Klade, Christoph, Georgiev, Pencho, Krochmalczyk, Dorota, Gercheva-Kyuchukova, Liana, Egyed, Miklos, Dulicek, Petr, Illes, Arpad, Pylypenko, Halyna, Sivcheva, Lylia, Mayer, Jiří, Yablokova, Vera, Krejcy, Kurt, Empson, Victoria, Hasselbalch, Hans C., Kralovics, Robert, Kiladjian, Jean-Jacques
Publicado 2023

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

por Nivarthi, Harini, Gordziel, Claire, Themanns, Madeleine, Kramer, Nina, Eberl, Markus, Rabe, Björn, Schlederer, Michaela, Rose-John, Stefan, Knösel, Thomas, Kenner, Lukas, Freund, Patricia, Aberger, Fritz, Han, Xiaonan, Kralovics, Robert, Dolznig, Helmut, Jennek, Susanne, Friedrich, Karlheinz, Moriggl, Richard
Publicado 2016

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

por Moder, Martin, Velimezi, Georgia, Owusu, Michel, Mazouzi, Abdelghani, Wiedner, Marc, Ferreira da Silva, Joana, Robinson-Garcia, Lydia, Schischlik, Fiorella, Slavkovsky, Rastislav, Kralovics, Robert, Schuster, Michael, Bock, Christoph, Ideker, Trey, Jackson, Stephen P., Menche, Jörg, Loizou, Joanna I.
Publicado 2017

Correction: The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

por Nivarthi, Harini, Gordziel, Claire, Themanns, Madeleine, Kramer, Nina, Eberl, Markus, Rabe, Björn, Schlederer, Michaela, Rose-John, Stefan, Knösel, Thomas, Kenner, Lukas, Freund, Patricia, Aberger, Fritz, Han, Xiaonan, Kralovics, Robert, Dolznig, Helmut, Jennek, Susanne, Friedrich, Karlheinz, Moriggl, Richard
Publicado 2018

Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age Groups

por Gisslinger, Heinz, Klade, Christoph, Georgiev, Pencho, Krochmalczyk, Dorota, Gercheva-Kyuchukova, Liana, Egyed, Miklos, Rossiev, Viktor, Dulicek, Petr, Illes, Arpad, Pylypenko, Halyna, Sivcheva, Lylia, Mayer, Jiri, Yablokova, Vera, Krejcy, Kurt, Hasselbalch, Hans C., Kralovics, Robert, Kiladjian, Jean-Jacques
Publicado 2020

Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

por Kiladjian, Jean-Jacques, Klade, Christoph, Georgiev, Pencho, Krochmalczyk, Dorota, Gercheva-Kyuchukova, Liana, Egyed, Miklos, Dulicek, Petr, Illes, Arpad, Pylypenko, Halyna, Sivcheva, Lylia, Mayer, Jiří, Yablokova, Vera, Krejcy, Kurt, Empson, Victoria, Hasselbalch, Hans C., Kralovics, Robert, Gisslinger, Heinz
Publicado 2022

PD‐L1 overexpression correlates with JAK2‐V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasms

por Milosevic Feenstra, Jelena D., Jäger, Roland, Schischlik, Fiorella, Ivanov, Daniel, Eisenwort, Gregor, Rumi, Elisa, Schuster, Michael, Gisslinger, Bettina, Machherndl‐Spandl, Sigrid, Bettelheim, Peter, Krauth, Maria‐Theresa, Keil, Felix, Bock, Christoph, Cazzola, Mario, Gisslinger, Heinz, Kralovics, Robert, Valent, Peter
Publicado 2022

A Downstream CpG Island Controls Transcript Initiation and Elongation and the Methylation State of the Imprinted Airn Macro ncRNA Promoter

por Koerner, Martha V., Pauler, Florian M., Hudson, Quanah J., Santoro, Federica, Sawicka, Anna, Guenzl, Philipp M., Stricker, Stefan H., Schichl, Yvonne M., Latos, Paulina A., Klement, Ruth M., Warczok, Katarzyna E., Wojciechowski, Jacek, Seiser, Christian, Kralovics, Robert, Barlow, Denise P.
Publicado 2012