Systemic Administration of Glibenclamide Fails to Achieve Therapeutic Levels in the Brain and Cerebrospinal Fluid of Rodents

por Lahmann, Carolina, Kramer, Holger B., Ashcroft, Frances M.
Publicado 2015

Correction: Systemic Administration of Glibenclamide Fails to Achieve Therapeutic Levels in the Brain and Cerebrospinal Fluid of Rodents

por Lahmann, Carolina, Kramer, Holger B., Ashcroft, Frances M.
Publicado 2019

Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation

por Hess, Wilfried, Mackeen, Mukram M., Kramer, Holger B.
Publicado 2016

Detection of ubiquitin–proteasome enzymatic activities in cells: Application of activity-based probes to inhibitor development()

por Kramer, Holger B., Nicholson, Benjamin, Kessler, Benedikt M., Altun, Mikael
Publicado 2012

Label-free quantitative proteomics reveals regulation of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) and 5'-3'-exoribonuclease 2 (XRN2) during respiratory s...

por Ternette, Nicola, Wright, Cynthia, Kramer, Holger B, Altun, Mikael, Kessler, Benedikt M
Publicado 2011

Probing enzymatic activity – a radical approach

por Taylor, Neil C., Hessman, Gary, Kramer, Holger B., McGouran, Joanna F.
Publicado 2020

Proteomics-based Identification of Novel Factor Inhibiting Hypoxia-inducible Factor (FIH) Substrates Indicates Widespread Asparaginyl Hydroxylation of Ankyrin Repeat Domain-contain...

por Cockman, Matthew E., Webb, James D., Kramer, Holger B., Kessler, Benedikt M., Ratcliffe, Peter J.
Publicado 2009

Deubiquitinating Enzyme Specificity for Ubiquitin Chain Topology Profiled by Di-Ubiquitin Activity Probes

por McGouran, Joanna F., Gaertner, Selina R., Altun, Mikael, Kramer, Holger B., Kessler, Benedikt M.
Publicado 2013

Off‐target inhibition of NGLY1 by the polycaspase inhibitor Z‐VAD‐fmk induces cellular autophagy

por Needs, Sarah H., Bootman, Martin D., Grotzke, Jeff E., Kramer, Holger B., Allman, Sarah A.
Publicado 2022

Solvent Precipitation SP3 (SP4) Enhances Recovery for Proteomics Sample Preparation without Magnetic Beads

por Johnston, Harvey E., Yadav, Kranthikumar, Kirkpatrick, Joanna M., Biggs, George S., Oxley, David, Kramer, Holger B., Samant, Rahul S.
Publicado 2022

Systemic muscle wasting and coordinated tumour response drive tumourigenesis

por Newton, Holly, Wang, Yi-Fang, Camplese, Laura, Mokochinski, Joao B., Kramer, Holger B., Brown, André E. X., Fets, Louise, Hirabayashi, Susumu
Publicado 2020

Changes in Gene Expression Associated with FTO Overexpression in Mice

por Merkestein, Myrte, McTaggart, James S., Lee, Sheena, Kramer, Holger B., McMurray, Fiona, Lafond, Mathilde, Boutens, Lily, Cox, Roger, Ashcroft, Frances M.
Publicado 2014

Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor

por Tarhonskaya, Hanna, Hardy, Adam P., Howe, Emily A., Loik, Nikita D., Kramer, Holger B., McCullagh, James S. O., Schofield, Christopher J., Flashman, Emily
Publicado 2015

Sex Differences in Intestinal Carbohydrate Metabolism Promote Food Intake and Sperm Maturation

por Hudry, Bruno, de Goeij, Eva, Mineo, Alessandro, Gaspar, Pedro, Hadjieconomou, Dafni, Studd, Chris, Mokochinski, Joao B., Kramer, Holger B., Plaçais, Pierre-Yves, Preat, Thomas, Miguel-Aliaga, Irene
Publicado 2019

The presence of prolines in the flanking region of an immunodominant HIV‐2 gag epitope influences the quality and quantity of the epitope generated

por Jallow, Sabelle, Leligdowicz, Aleksandra, Kramer, Holger B., Onyango, Clayton, Cotten, Matthew, Wright, Cynthia, Whittle, Hilton C., McMichael, Andrew, Dong, Tao, Kessler, Benedikt M., Rowland‐Jones, Sarah L.
Publicado 2015

The Human Otubain2-Ubiquitin Structure Provides Insights into the Cleavage Specificity of Poly-Ubiquitin-Linkages

por Altun, Mikael, Walter, Thomas S., Kramer, Holger B., Herr, Patrick, Iphöfer, Alexander, Boström, Johan, David, Yael, Komsany, Alia, Ternette, Nicola, Navon, Ami, Stuart, David I., Ren, Jingshan, Kessler, Benedikt M.
Publicado 2015

Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors

por Tian, Ya-Min, Yeoh, Kar Kheng, Lee, Myung Kyu, Eriksson, Tuula, Kessler, Benedikt M., Kramer, Holger B., Edelmann, Mariola J., Willam, Carsten, Pugh, Christopher W., Schofield, Christopher J., Ratcliffe, Peter J.
Publicado 2011

Antibodies to GABA(A) receptor α1 and γ2 subunits: Clinical and serologic characterization

por Pettingill, Philippa, Kramer, Holger B., Coebergh, Jan Adriaan, Pettingill, Rosie, Maxwell, Susan, Nibber, Anjan, Malaspina, Andrea, Jacob, Anu, Irani, Sarosh R., Buckley, Camilla, Beeson, David, Lang, Bethan, Waters, Patrick, Vincent, Angela
Publicado 2015

Use of Modified Clostridium perfringens Enterotoxin Fragments for Claudin Targeting in Liver and Skin Cells

por Beier, Laura-Sophie, Rossa, Jan, Woodhouse, Stephen, Bergmann, Sophia, Kramer, Holger B., Protze, Jonas, Eichner, Miriam, Piontek, Anna, Vidal-y-Sy, Sabine, Brandner, Johanna M., Krause, Gerd, Zitzmann, Nicole, Piontek, Jörg
Publicado 2019

Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor

por Yang, Ming, Ge, Wei, Chowdhury, Rasheduzzaman, Claridge, Timothy D. W., Kramer, Holger B., Schmierer, Bernhard, McDonough, Michael A., Gong, Lingzhi, Kessler, Benedikt M., Ratcliffe, Peter J., Coleman, Mathew L., Schofield, Christopher J.
Publicado 2011