Regrowing axons with alternative splicing

por Kramer, Nicholas J, Gitler, Aaron D
Publicado 2016

LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

por Bieri, Gregor, Brahic, Michel, Bousset, Luc, Couthouis, Julien, Kramer, Nicholas J., Ma, Rosanna, Nakayama, Lisa, Monbureau, Marie, Defensor, Erwin, Schüle, Birgitt, Shamloo, Mehrdad, Melki, Ronald, Gitler, Aaron D.
Publicado 2019

A versatile system to record cell-cell interactions

por Tang, Rui, Murray, Christopher W, Linde, Ian L, Kramer, Nicholas J, Lyu, Zhonglin, Tsai, Min K, Chen, Leo C, Cai, Hongchen, Gitler, Aaron D, Engleman, Edgar, Lee, Wonjae, Winslow, Monte M
Publicado 2020

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.

por Goodman, Lindsey D., Prudencio, Mercedes, Kramer, Nicholas J., Martinez-Ramirez, Luis F., Srinivasan, Ananth R., Lan, Matthews, Parisi, Michael J., Zhu, Yongqing, Chew, Jeannie, Cook, Casey N., Berson, Amit, Gitler, Aaron D., Petrucelli, Leonard, Bonini, Nancy M.
Publicado 2019

Modifiers of C9orf72 DPR toxicity implicate nucleocytoplasmic transport impairments in c9FTD/ALS

por Jovičić, Ana, Mertens, Jerome, Boeynaems, Steven, Bogaert, Elke, Chai, Noori, Yamada, Shizuka B., Paul, Joseph W., Sun, Shuying, Herdy, Joseph R., Bieri, Gregor, Kramer, Nicholas J., Gage, Fred H., Den Bosch, Ludo Van, Robberecht, Wim, Gitler, Aaron D.
Publicado 2015

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9orf72 dipeptide repeat protein toxicity

por Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly, Shi, Yingxiao, Hertz, Nicholas T., Tessier-Lavigne, Marc, Ichida, Justin K., Bassik, Michael C., Gitler, Aaron D.
Publicado 2018

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

por Yamada, Shizuka B., Gendron, Tania F., Niccoli, Teresa, Genuth, Naomi R., Grosely, Rosslyn, Shi, Yingxiao, Glaria, Idoia, Kramer, Nicholas J., Nakayama, Lisa, Fang, Shirleen, Dinger, Tai J. I., Thoeng, Annora, Rocha, Gabriel, Barna, Maria, Puglisi, Joseph D., Partridge, Linda, Ichida, Justin K., Isaacs, Adrian M., Petrucelli, Leonard, Gitler, Aaron D.
Publicado 2019