Ocular Distribution of Cyclosporine Following Topical Administration of OTX-101 in New Zealand White Rabbits

por Weiss, Sidney L., Kramer, William G.
Publicado 2019

Pharmacokinetics of the Dual Melatonin Receptor Agonist Tasimelteon in Subjects With Hepatic or Renal Impairment

por Torres, Rosarelis, Kramer, William G, Baroldi, Paolo
Publicado 2015

The effects of sitaxentan on sildenafil pharmacokinetics and pharmacodynamics in healthy subjects

por Stavros, Fiona, Kramer, William G, Wilkins, Martin R
Publicado 2010

Evaluation of potential drug interactions with sodium zirconium cyclosilicate: a single-center, open-label, one sequence crossover study in healthy adults

por Någård, Mats, Kramer, William G, Boulton, David W
Publicado 2020

Bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers

por Parikh, Neha, Kramer, William G, Khurana, Varun, Cognata Smith, Christina, Vetticaden, Santosh
Publicado 2016

Marked decline in serum digoxin concentrations during an episode of severe diarrhea()

por Kolibash, Albert J., Kramer, William G., Reuning, Richard H., Caldwell, James H.
Publicado 1977

1340. Population Pharmacokinetic (PK) Analysis of APX001 Using Phase 1 Data

por Trang, Michael, Bader, Justin C, Ople, Eric A, Kramer, William G, Hodges, Michael R, Bhavnani, Sujata M, Rubino, Christopher M
Publicado 2018

Phase 1b safety and pharmacokinetics of intravenous and oral fosmanogepix in patients with acute myeloid leukaemia and neutropenia

por Cornely, Oliver A, Ostermann, Helmut, Koehler, Philipp, Teschner, Daniel, Limburg, Endrik, Kramer, William G, Barbat, Sara H, Tawadrous, Margaret, Hodges, Michael R
Publicado 2023

A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin

por Goldwater, Ronald, Kramer, William G, Hamilton, Douglas A, Lang, Eric, Wang, Jianyuan, Madden, Donna E, Lacouture, Peter G, Ramaiya, Atulkumar, Carr, Daniel B
Publicado 2016

Pharmacokinetics of Diclofenac and Hydroxypropyl‐β‐Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD‐Diclofenac in Subjects With Mild to Moderate Renal Insufficienc...

por Hamilton, Douglas A., Ernst, Cynthia C., Kramer, William G., Madden, Donna, Lang, Eric, Liao, Edward, Lacouture, Peter G., Ramaiya, Atulkumar, Carr, Daniel B.
Publicado 2017

Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

por Hodges, Michael R., Ople, Eric, Wedel, Pamela, Shaw, Karen J., Jakate, Abhijeet, Kramer, William G., van Marle, Sjoerd, van Hoogdalem, Ewoud-Jan, Tawadrous, Margaret
Publicado 2023

A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers

por Karpecki, Paul M, Weiss, Sidney L, Kramer, William G, O’Connor, Patrick, Evans, David, Johnston, Josh, Jasper, April L, Justice, Angela, Ogundele, Abayomi B, Devries, Doug
Publicado 2019

Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes

por Hoffman, Eric P., Riddle, Valerie, Siegler, Maxime A., Dickerson, Daniel, Backonja, Miroslav, Kramer, William G., Nagaraju, Kanneboyina, Gordish-Dressman, Heather, Damsker, Jesse M., McCall, John M.
Publicado 2018