Relieving oxidative stress in immune cells

por Kranc, Kamil R., Dzierzak, Elaine
Publicado 2015

Ca(2+)tapulting HSCs into action

por Guitart, Amelie V., Finch, Andrew J., Kranc, Kamil R.
Publicado 2018

Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism

por Yang, Ming, Su, Huizhong, Soga, Tomoyoshi, Kranc, Kamil R, Pollard, Patrick J
Publicado 2014

CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands

por van de Lagemaat, Louie N., Flenley, Maria, Lynch, Magnus D., Garrick, David, Tomlinson, Simon R., Kranc, Kamil R., Vernimmen, Douglas
Publicado 2018

A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells

por Turner, David J, Saveliev, Alexander, Salerno, Fiamma, Matheson, Louise S, Screen, Michael, Lawson, Hannah, Wotherspoon, David, Kranc, Kamil R, Turner, Martin
Publicado 2022

Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis

por Young, Christine, Russell, John R., Van De Lagemaat, Louie N., Lawson, Hannah, Mapperley, Christopher, Kranc, Kamil R., Christophorou, Maria A.
Publicado 2022

Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny

por Calaminus, Simon D. J., Guitart, Amelie, Sinclair, Amy, Schachtner, Hannah, Watson, Steve P., Holyoake, Tessa L., Kranc, Kamil R., Machesky, Laura M.
Publicado 2012

Correction: Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny

por Calaminus, Simon D. J., Guitart, Amelie V., Sinclair, Amy, Schachtner, Hannah, Watson, Steve P., Holyoake, Tessa L., Kranc, Kamil R., Machesky, Laura M.
Publicado 2013

Cited2 Is an Essential Regulator of Adult Hematopoietic Stem Cells

por Kranc, Kamil R., Schepers, Hein, Rodrigues, Neil P., Bamforth, Simon, Villadsen, Ellen, Ferry, Helen, Bouriez-Jones, Tiphaine, Sigvardsson, Mikael, Bhattacharya, Shoumo, Jacobsen, Sten Eirik, Enver, Tariq
Publicado 2009

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

por Mortensen, Monika, Soilleux, Elizabeth J., Djordjevic, Gordana, Tripp, Rebecca, Lutteropp, Michael, Sadighi-Akha, Elham, Stranks, Amanda J., Glanville, Julie, Knight, Samantha, W. Jacobsen, Sten-Eirik, Kranc, Kamil R., Simon, Anna Katharina
Publicado 2011

ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

por Karvela, Maria, Baquero, Pablo, Kuntz, Elodie M., Mukhopadhyay, Arunima, Mitchell, Rebecca, Allan, Elaine K., Chan, Edmond, Kranc, Kamil R., Calabretta, Bruno, Salomoni, Paolo, Gottlieb, Eyal, Holyoake, Tessa L., Helgason, G. Vignir
Publicado 2016

Acute Loss of Cited2 Impairs Nanog Expression and Decreases Self-Renewal of Mouse Embryonic Stem Cells

por Kranc, Kamil R, Oliveira, Daniel V, Armesilla-Diaz, Alejandro, Pacheco-Leyva, Ivette, Catarina Matias, Ana, Luisa Escapa, Ana, Subramani, Chithra, Wheadon, Helen, Trindade, Marlene, Nichols, Jennifer, Kaji, Keisuke, Enver, Tariq, Bragança, José
Publicado 2015

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

por Codino, Azzurra, Turowski, Tomasz, van de Lagemaat, Louie N., Ivanova, Ivayla, Tavosanis, Andrea, Much, Christian, Auchynnikava, Tania, Vasiliauskaitė, Lina, Morgan, Marcos, Rappsilber, Juri, Allshire, Robin C., Kranc, Kamil R., Tollervey, David, O'Carroll, Dónal
Publicado 2021

Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia

por Menendez-Gonzalez, Juan Bautista, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-anne, Agirre-Lizaso, Aloña, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah, Kong, Kay, Giles, Peter, Anjos-Afonso, Fernando, Tonks, Alex, Boyd, Ashleigh S., Kranc, Kamil R., Rodrigues, Neil P.
Publicado 2019

Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability

por Woodward, Jessica, Taylor, Gillian C., Soares, Dinesh C., Boyle, Shelagh, Sie, Daoud, Read, David, Chathoth, Keerthi, Vukovic, Milica, Tarrats, Nuria, Jamieson, David, Campbell, Kirsteen J., Blyth, Karen, Acosta, Juan Carlos, Ylstra, Bauke, Arends, Mark J., Kranc, Kamil R., Jackson, Andrew P., Bickmore, Wendy A., Wood, Andrew J.
Publicado 2016

The mRNA m(6)A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function

por Mapperley, Christopher, van de Lagemaat, Louie N., Lawson, Hannah, Tavosanis, Andrea, Paris, Jasmin, Campos, Joana, Wotherspoon, David, Durko, Jozef, Sarapuu, Annika, Choe, Junho, Ivanova, Ivayla, Krause, Daniela S., von Kriegsheim, Alex, Much, Christian, Morgan, Marcos, Gregory, Richard I., Mead, Adam J., O’Carroll, Dónal, Kranc, Kamil R.
Publicado 2020

CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation

por Lawson, Hannah, van de Lagemaat, Louie N., Barile, Melania, Tavosanis, Andrea, Durko, Jozef, Villacreces, Arnaud, Bellani, Aarushi, Mapperley, Christopher, Georges, Elise, Martins-Costa, Catarina, Sepulveda, Catarina, Allen, Lewis, Campos, Joana, Campbell, Kirsteen J., O'Carroll, Dónal, Göttgens, Berthold, Cory, Suzanne, Rodrigues, Neil P., Guitart, Amelie V., Kranc, Kamil R.
Publicado 2021

Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death

por Woodley, Keith, Dillingh, Laura S., Giotopoulos, George, Madrigal, Pedro, Rattigan, Kevin M., Philippe, Céline, Dembitz, Vilma, Magee, Aoife M. S., Asby, Ryan, van de Lagemaat, Louie N., Mapperley, Christopher, James, Sophie C., Prehn, Jochen H. M., Tzelepis, Konstantinos, Rouault-Pierre, Kevin, Vassiliou, George S., Kranc, Kamil R., Helgason, G. Vignir, Huntly, Brian J. P., Gallipoli, Paolo
Publicado 2023

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance

por Vukovic, Milica, Guitart, Amelie V., Sepulveda, Catarina, Villacreces, Arnaud, O'Duibhir, Eoghan, Panagopoulou, Theano I., Ivens, Alasdair, Menendez-Gonzalez, Juan, Iglesias, Juan Manuel, Allen, Lewis, Glykofrydis, Fokion, Subramani, Chithra, Armesilla-Diaz, Alejandro, Post, Annemarie E.M., Schaak, Katrin, Gezer, Deniz, So, Chi Wai Eric, Holyoake, Tessa L., Wood, Andrew, O'Carroll, Dónal, Ratcliffe, Peter J., Kranc, Kamil R.
Publicado 2015

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

por Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Publicado 2019