Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting

por Aristin Revilla, Sonia, Kranenburg, Onno, Coffer, Paul J.
Publicado 2022

A potential role for CCN2/CTGF in aggressive colorectal cancer

por Ubink, Inge, Verhaar, Elisha R., Kranenburg, Onno, Goldschmeding, Roel
Publicado 2016

Peritoneal Metastases From Colorectal Cancer: Defining and Addressing the Challenges

por Kranenburg, Onno, van der Speeten, Kurt, de Hingh, Ignace
Publicado 2021

Common anti-cancer therapies induce somatic mutations in stem cells of healthy tissue

por Kuijk, Ewart, Kranenburg, Onno, Cuppen, Edwin, Van Hoeck, Arne
Publicado 2022

NOXA-dependent contextual synthetic lethality of BCL-XL inhibition and “osmotic reprogramming” in colorectal cancer

por Knoll, Gertrud, Riffelsberger, Petra, Raats, Danielle, Kranenburg, Onno, Ehrenschwender, Martin
Publicado 2020

ALDH1A1 expression is associated with poor differentiation, ‘right-sidedness’ and poor survival in human colorectal cancer

por van der Waals, Lizet M., Borel Rinkes, Inne H. M., Kranenburg, Onno
Publicado 2018

Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes

por Gerlach, Jan P., Emmink, Benjamin L., Nojima, Hisashi, Kranenburg, Onno, Maurice, Madelon M.
Publicado 2014

Paired image- and FACS-based toxicity assays for high content screening of spheroid-type tumor cell cultures

por Trumpi, Kari, Egan, David A., Vellinga, Thomas T., Borel Rinkes, Inne H.M., Kranenburg, Onno
Publicado 2015

Loss of Neuropilin-2 in Murine Mesenchymal-like Colon Cancer Organoids Causes Mesenchymal-to-Epithelial Transition and an Acquired Dependency on Insulin-Receptor Signaling and Auto...

por Poghosyan, Susanna, Frenkel, Nicola, Lentzas, Aristeidis, Laoukili, Jamila, Rinkes, Inne Borel, Kranenburg, Onno, Hagendoorn, Jeroen
Publicado 2022

CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage

por Raats, Danielle A, Frenkel, Nicola, van Schelven, Susanne J, Rinkes, Inne HMBorel, Laoukili, Jamila, Kranenburg, Onno
Publicado 2017

Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

por Koeberle, Solveigh C., Gollowitzer, André, Laoukili, Jamila, Kranenburg, Onno, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P.
Publicado 2019

A Potential Role for HUWE1 in Modulating Cisplatin Sensitivity

por Wenmaekers, Stijn, Viergever, Bastiaan J., Kumar, Gunjan, Kranenburg, Onno, Black, Peter C., Daugaard, Mads, Meijer, Richard P.
Publicado 2021

Differential Notch and TGFβ Signaling in Primary Colorectal Tumors and Their Corresponding Metastases

por Veenendaal, Liesbeth M., Kranenburg, Onno, Smakman, Niels, Klomp, Annemarie, Borel Rinkes, Inne H. M., van Diest, Paul J.
Publicado 2008

Detection of Experimental Colorectal Peritoneal Metastases by a Novel PDGFRβ-Targeting Nanobody

por Strating, Esther, Elias, Sjoerd, van Scharrenburg, Guus, Luoto, Kaisa, Verheem, André, Borel Rinkes, Inne, Steen, Herman, Kranenburg, Onno
Publicado 2022

Identification of a Novel, Putative Rho-specific GDP/GTP Exchange Factor and a RhoA-binding Protein: Control of Neuronal Morphology

por Gebbink, Martijn F.B.G., Kranenburg, Onno, Poland, Mieke, van Horck, Francis P.G., Houssa, Brahim, Moolenaar, Wouter H.
Publicado 1997

Liver lymphatic drainage patterns follow segmental anatomy in a murine model

por Frenkel, Nicola C., Poghosyan, Susanna, Verheem, André, Padera, Timothy P., Rinkes, Inne H. M. Borel, Kranenburg, Onno, Hagendoorn, Jeroen
Publicado 2020

The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho

por van Leeuwen, Frank N., Kain, Hendrie E.T., van der Kammen, Rob A., Michiels, Frits, Kranenburg, Onno W., Collard, John G.
Publicado 1997

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

por Wensink, G. Emerens, Elias, Sjoerd G., Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F., Kranenburg, Onno W., Roodhart, Jeanine M. L.
Publicado 2021

KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

por Küçükköse, Emre, Peters, Niek A., Ubink, Inge, van Keulen, Veere A. M., Daghighian, Roxanna, Verheem, André, Laoukili, Jamila, Kranenburg, Onno
Publicado 2022

Molecular Dissection of the Rho-associated Protein Kinase (p160ROCK)-regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells

por Hirose, Masaya, Ishizaki, Toshimasa, Watanabe, Naoki, Uehata, Masayoshi, Kranenburg, Onno, Moolenaar, Wouter H., Matsumura, Fumio, Maekawa, Midori, Bito, Haruhiko, Narumiya, Shuh
Publicado 1998