Testis Sparing Surgery in Pediatric Testicular Tumors

por Kooij, Cezanne D., Hulsker, Caroline C.C., Kranendonk, Mariëtte E.G., Zsiros, József, Littooij, Annemieke S., Looijenga, Leendert H.J., Klijn, Aart J., Mavinkurve-Groothuis, Annelies M.C.
Publicado 2020

A Toolkit for Profiling the Immune Landscape of Pediatric Central Nervous System Malignancies

por Rozowsky, Jacob S., Meesters-Ensing, Joyce I., Lammers, Julie A. S., Belle, Muriël L., Nierkens, Stefan, Kranendonk, Mariëtte E. G., Kester, Lennart A., Calkoen, Friso G., van der Lugt, Jasper
Publicado 2022

IMMU-05. Integrative transcriptomic analysis of pilocytic astrocytomas reveals CNS region-associated characteristics

por Rozowsky, Jacob S, Kranendonk, Mariëtte E G, van Meeteren, Antoinette Y N Schouten-, Meijer, Lisethe, Hoving, Eelco W, Calkoen, Friso G, Wesseling, Pieter, Kester, Lennart A, van der Lugt, Jasper
Publicado 2022

LGG-15. SINGLE-NUCLEUS AND BULK RNA SEQUENCING OF PEDIATRIC PILOCYTIC ASTROCYTOMAS REVEALS CNS LOCATION-ASSOCIATED TUMOR CELL AND MICROENVIRONMENTAL HETEROGENEITY

por Lammers, Julie A S, Rozowsky, Jacob S, Kranendonk, Mariëtte E G, Schouten-van Meeteren, Antoinette Y N, Meijer, Lisethe, Calkoen, Friso G, Hoving, Eelco W, Wesseling, Pieter, van der Lugt, Jasper, Kester, Lennart A
Publicado 2023

The decisive role of molecular pathology in presumed somatic metastases of type II testicular germ cell tumors: report of 2 cases

por Kranendonk, Mariëtte E. G., Hackeng, Wenzel M., Offerhaus, G. Johan A., Morsink, Folkert H. M., Jonges, Geertruida N., Groenewegen, Gerard, Krijtenburg, Pieter-Jaap, Klümpen, Heinz-Josef, de Leng, Wendy W. J., Looijenga, Leendert H. J., Brosens, Lodewijk A. A.
Publicado 2020

Recurrence of a Mediastinal Germ-Cell Tumor as a Somatic-Type Malignancy: A Complex Case Report

por Hulsker, Caroline C. C., Kranendonk, Mariëtte E. G., Eleveld, Thomas F., Gillis, Ad J. M., van de Ven, Cornelis P., van Eijkelenburg, Natasha K. A., van der Kaaij, Niels P., van der Steeg, Alida F. W., Looijenga, Leendert H. J.
Publicado 2021

BIOL-14. FROM NON-MALIGNANT TO MALIGNANT: GENERATING AND TARGETING DIFFUSE MIDLINE GLIOMA IN A NOVEL HUMAN PONTINE ORGANOID MODEL

por Bessler, Nils, Moreno, Cristian Ruiz, Wezenaar, Amber, Dommann, Noëlle, Keramati, Farid, Ariese, Hendrikus C R, Honhoff, Celina, de Blank, Sam, Román, Mario Barrera, Collot, Raphaël, van Ineveld, Ravian, Krashennikova, Maria Alieva, Kranendonk, Mariette E G, Wehrens, Ellen J, Alemany, Anna, Stunnenberg, Henk G, Rios, Anne C
Publicado 2023

Improved Gene Fusion Detection in Childhood Cancer Diagnostics Using RNA Sequencing

por Hehir-Kwa, Jayne Y., Koudijs, Marco J., Verwiel, Eugene T. P., Kester, Lennart A., van Tuil, Marc, Strengman, Eric, Buijs, Arjan, Kranendonk, Mariëtte E. G., Hiemcke-Jiwa, Laura S., de Haas, Valerie, van de Geer, Ellen, de Leng, Wendy, van der Lugt, Jasper, Lijnzaad, Philip, Holstege, Frank C. P., Kemmeren, Patrick, Tops, Bastiaan B. J.
Publicado 2022

OTHR-41. Amplification of the PLAG family genes – PLAGL1 and PLAGL2 – is a key feature of a novel embryonal CNS tumor type

por Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Kumar, Piyush Joshi, Stichel, Damian, Sievers, Philipp, Wefers, Annika K, Roncaroli, Federico, Hayden, James, McCabe, Martin G, Kranendonk, Mariëtte E G, Zapotocky, Michal, Vasiljevic, Alexandre, Schüller, Ulrich, Sturm, Dominik, Blattner-Johnson, Mirjam, von Deimling, Andreas, Korshunov, Andrey, Sahm, Felix, Perry, Arie, Solomon, David, Pfister, Stefan, Jones, David T W
Publicado 2022

GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types

por Sievers, Philipp, Stichel, Damian, Sill, Martin, Schrimpf, Daniel, Sturm, Dominik, Selt, Florian, Ecker, Jonas, Kazdal, Daniel, Miele, Evelina, Kranendonk, Mariëtte E. G., Tops, Bastiaan B. J., Kohlhof-Meinecke, Patricia, Beschorner, Rudi, Kramm, Christof M., Hasselblatt, Martin, Reifenberger, Guido, Capper, David, Wesseling, Pieter, Stenzinger, Albrecht, Milde, Till, Korshunov, Andrey, Witt, Olaf, Pfister, Stefan M., Wick, Wolfgang, von Deimling, Andreas, Jones, David T. W., Sahm, Felix
Publicado 2021

PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation

por Madsen, Maria Stahl, Broekema, Marjoleine F., Madsen, Martin Rønn, Koppen, Arjen, Borgman, Anouska, Gräwe, Cathrin, Thomsen, Elisabeth G. K., Westland, Denise, Kranendonk, Mariette E. G., Koerkamp, Marian Groot, Hamers, Nicole, Bonvin, Alexandre M. J. J., Pittol, José M. Ramos, Natarajan, Kedar Nath, Kersten, Sander, Holstege, Frank C. P., Monajemi, Houshang, van Mil, Saskia W. C., Vermeulen, Michiel, Kragelund, Birthe B., Cassiman, David, Mandrup, Susanne, Kalkhoven, Eric
Publicado 2022

Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

por Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Joshi, Piyush, Stichel, Damian, Beck, Pengbo, Okonechnikow, Konstantin, Sievers, Philipp, Wefers, Annika K., Roncaroli, Federico, Avula, Shivaram, McCabe, Martin G., Hayden, James T., Wesseling, Pieter, Øra, Ingrid, Nistér, Monica, Kranendonk, Mariëtte E. G., Tops, Bastiaan B. J., Zapotocky, Michal, Zamecnik, Josef, Vasiljevic, Alexandre, Fenouil, Tanguy, Meyronet, David, von Hoff, Katja, Schüller, Ulrich, Loiseau, Hugues, Figarella-Branger, Dominique, Kramm, Christof M., Sturm, Dominik, Scheie, David, Rauramaa, Tuomas, Pesola, Jouni, Gojo, Johannes, Haberler, Christine, Brandner, Sebastian, Jacques, Tom, Sexton Oates, Alexandra, Saffery, Richard, Koscielniak, Ewa, Baker, Suzanne J., Yip, Stephen, Snuderl, Matija, Ud Din, Nasir, Samuel, David, Schramm, Kathrin, Blattner-Johnson, Mirjam, Selt, Florian, Ecker, Jonas, Milde, Till, von Deimling, Andreas, Korshunov, Andrey, Perry, Arie, Pfister, Stefan M., Sahm, Felix, Solomon, David A., Jones, David T. W.
Publicado 2023

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

por Sievers, Philipp, Henneken, Sophie C., Blume, Christina, Sill, Martin, Schrimpf, Daniel, Stichel, Damian, Okonechnikov, Konstantin, Reuss, David E., Benzel, Julia, Maaß, Kendra K., Kool, Marcel, Sturm, Dominik, Zheng, Tuyu, Ghasemi, David R., Kohlhof-Meinecke, Patricia, Cruz, Ofelia, Suñol, Mariona, Lavarino, Cinzia, Ruf, Viktoria, Boldt, Henning B., Pagès, Mélanie, Pouget, Celso, Schweizer, Leonille, Kranendonk, Mariëtte E. G., Akhtar, Noreen, Bunkowski, Stephanie, Stadelmann , Christine, Schüller, Ulrich, Mueller, Wolf C., Dohmen, Hildegard, Acker, Till, Harter, Patrick N., Mawrin, Christian, Beschorner, Rudi, Brandner, Sebastian, Snuderl, Matija, Abdullaev, Zied, Aldape, Kenneth, Gilbert, Mark R., Armstrong, Terri S., Ellison, David W., Capper, David, Ichimura, Koichi, Reifenberger, Guido, Grundy, Richard G., Jabado, Nada, Krskova, Lenka, Zapotocky, Michal, Vicha, Ales, Varlet, Pascale, Wesseling, Pieter, Rutkowski, Stefan, Korshunov, Andrey, Wick, Wolfgang, Pfister, Stefan M., Jones, David T. W., von Deimling, Andreas, Pajtler, Kristian W., Sahm, Felix
Publicado 2021

Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

por Keck, Michaela-Kristina, Sill, Martin, Wittmann, Andrea, Joshi, Piyush, Stichel, Damian, Beck, Pengbo, Okonechnikow, Konstantin, Sievers, Philipp, Wefers, Annika K., Roncaroli, Federico, Avula, Shivaram, McCabe, Martin G., Hayden, James T., Wesseling, Pieter, Øra, Ingrid, Nistér, Monica, Kranendonk, Mariëtte E. G., Tops, Bastiaan B. J., Zapotocky, Michal, Zamecnik, Josef, Vasiljevic, Alexandre, Fenouil, Tanguy, Meyronet, David, von Hoff, Katja, Schüller, Ulrich, Loiseau, Hugues, Figarella-Branger, Dominique, Kramm, Christof M., Sturm, Dominik, Scheie, David, Rauramaa, Tuomas, Pesola, Jouni, Gojo, Johannes, Haberler, Christine, Brandner, Sebastian, Jacques, Tom, Sexton Oates, Alexandra, Saffery, Richard, Koscielniak, Ewa, Baker, Suzanne J., Yip, Stephen, Snuderl, Matija, Ud Din, Nasir, Samuel, David, Schramm, Kathrin, Blattner-Johnson, Mirjam, Selt, Florian, Ecker, Jonas, Milde, Till, von Deimling, Andreas, Korshunov, Andrey, Perry, Arie, Pfister, Stefan M., Sahm, Felix, Solomon, David A., Jones, David T. W.
Publicado 2022

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum

por Alhalabi, Karam T., Stichel, Damian, Sievers, Philipp, Peterziel, Heike, Sommerkamp, Alexander C., Sturm, Dominik, Wittmann, Andrea, Sill, Martin, Jäger, Natalie, Beck, Pengbo, Pajtler, Kristian W., Snuderl, Matija, Jour, George, Delorenzo, Michael, Martin, Allison M., Levy, Adam, Dalvi, Nagma, Hansford, Jordan R., Gottardo, Nicholas G., Uro-Coste, Emmanuelle, Maurage, Claude-Alain, Godfraind, Catherine, Vandenbos, Fanny, Pietsch, Torsten, Kramm, Christof, Filippidou, Maria, Kattamis, Antonis, Jones, Chris, Øra, Ingrid, Mikkelsen, Torben Stamm, Zapotocky, Michal, Sumerauer, David, Scheie, David, McCabe, Martin, Wesseling, Pieter, Tops, Bastiaan B. J., Kranendonk, Mariëtte E. G., Karajannis, Matthias A., Bouvier, Nancy, Papaemmanuil, Elli, Dohmen, Hildegard, Acker, Till, von Hoff, Katja, Schmid, Simone, Miele, Evelina, Filipski, Katharina, Kitanovski, Lidija, Krskova, Lenka, Gojo, Johannes, Haberler, Christine, Alvaro, Frank, Ecker, Jonas, Selt, Florian, Milde, Till, Witt, Olaf, Oehme, Ina, Kool, Marcel, von Deimling, Andreas, Korshunov, Andrey, Pfister, Stefan M., Sahm, Felix, Jones, David T. W.
Publicado 2021

Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’

por Langenberg, Karin P.S., Meister, Michael T., Bakhuizen, Jette J., Boer, Judith M., van Eijkelenburg, Natasha K.A., Hulleman, Esther, Ilan, Uri, Looze, Eleonora J., Dierselhuis, Miranda P., van der Lugt, Jasper, Breunis, Willemijn, Schild, Linda G., Ober, Kimberley, van Hooff, Sander R., Scheijde-Vermeulen, Marijn A., Hiemcke-Jiwa, Laura S., Flucke, Uta E., Kranendonk, Mariette E.G., Wesseling, Pieter, Sonneveld, Edwin, Punt, Simone, Boltjes, Arjan, van Dijk, Freerk, Verwiel, Eugene T.P., Volckmann, Richard, Hehir-Kwa, Jayne Y., Kester, Lennart A., Koudijs, Marco M.J., Waanders, Esme, Holstege, Frank C.P., Vormoor, H. Josef, Hoving, Eelco W., van Noesel, Max M., Pieters, Rob, Kool, Marcel, Stumpf, Miriam, Blattner-Johnson, Mirjam, Balasubramanian, Gnana P., Van Tilburg, Cornelis M., Jones, Barbara C., Jones, David T.W., Witt, Olaf, Pfister, Stefan M., Jongmans, Marjolijn C.J., Kuiper, Roland P., de Krijger, Ronald R., Wijnen, Marc H.W., den Boer, Monique L., Zwaan, C. Michel, Kemmeren, Patrick, Koster, Jan, Tops, Bastiaan B.J., Goemans, Bianca F., Molenaar, Jan J.
Publicado 2022