The role of CaMKII regulation of phospholamban activity in heart disease

por Mattiazzi, Alicia, Kranias, Evangelia G.
Publicado 2014

Identification of a Protein Phosphatase-1/Phospholamban Complex That Is Regulated by cAMP-Dependent Phosphorylation

por Vafiadaki, Elizabeth, Arvanitis, Demetrios A., Sanoudou, Despina, Kranias, Evangelia G.
Publicado 2013

Aberrant PLN-R14del Protein Interactions Intensify SERCA2a Inhibition, Driving Impaired Ca(2+) Handling and Arrhythmogenesis

por Vafiadaki, Elizabeth, Haghighi, Kobra, Arvanitis, Demetrios A., Kranias, Evangelia G., Sanoudou, Despina
Publicado 2022

Phospholamban R14del disease: The past, the present and the future

por Vafiadaki, Elizabeth, Glijnis, Pieter C., Doevendans, Pieter A., Kranias, Evangelia G., Sanoudou, Despina
Publicado 2023

The Histidine-Rich Calcium Binding Protein in Regulation of Cardiac Rhythmicity

por Arvanitis, Demetrios A., Vafiadaki, Elizabeth, Johnson, Daniel M., Kranias, Evangelia G., Sanoudou, Despina
Publicado 2018

The Cardioprotective PKA-Mediated Hsp20 Phosphorylation Modulates Protein Associations Regulating Cytoskeletal Dynamics

por Vafiadaki, Elizabeth, Arvanitis, Demetrios A., Eliopoulos, Aristides G., Kranias, Evangelia G., Sanoudou, Despina
Publicado 2020

Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2

por Zhang, Xiaowei, Wang, Xiaohong, Zhu, Hongyan, Kranias, Evangelia G., Tang, Yaoliang, Peng, Tianqing, Chang, Jiang, Fan, Guo-Chang
Publicado 2012

Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy

por Onusko, Evan, McDermott, Michael R., Robbins, Nathan, Liu, Guansheng, Kranias, Evangelia G., Rubinstein, Jack, Koch, Sheryl E.
Publicado 2020

Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy

por Kumar, Mohit, Haghighi, Kobra, Koch, Sheryl, Rubinstein, Jack, Stillitano, Francesca, Hajjar, Roger J., Kranias, Evangelia G., Sadayappan, Sakthivel
Publicado 2023

3213 Unraveling the role of Phospholamban (PLN) in humans via the characterization of Induced Pluripotent Stem Cell (iPSC) Cardiomyocytes (CM) derived from carriers of a lethal PLN...

por Trivieri, Maria Giovanna, Stillitano, Francesca, Ceholski, Delaine, Turnbull, Irene, Costa, Kevin, Weber, Thomas, Fish, Kenneth, Kranias, Evangelia, Hajjar, Roger
Publicado 2019

Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca(2+) Homeostasis

por Boncompagni, Simona, Thomas, Monique, Lopez, Jose R., Allen, Paul D., Yuan, Qunying, Kranias, Evangelia G., Franzini-Armstrong, Clara, Perez, Claudio F.
Publicado 2012

AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure

por Park, Chang Sik, Cha, Hyeseon, Kwon, Eun Jeong, Jeong, Dongtak, Hajjar, Roger J., Kranias, Evangelia G., Cho, Chunghee, Park, Woo Jin, Kim, Do Han
Publicado 2012

A novel human S10F‐Hsp20 mutation induces lethal peripartum cardiomyopathy

por Liu, Guan‐Sheng, Gardner, George, Adly, George, Jiang, Min, Cai, Wen‐Feng, Lam, Chi Keung, Alogaili, Fawzi, Robbins, Nathan, Rubinstein, Jack, Kranias, Evangelia G.
Publicado 2018

Ankyrin-B Syndrome: Enhanced Cardiac Function Balanced by Risk of Cardiac Death and Premature Senescence

por Mohler, Peter J., Healy, Jane A., Xue, Hui, Puca, Annibale A., Kline, Crystal F., Rand Allingham, R., Kranias, Evangelia G., Rockman, Howard A., Bennett, Vann
Publicado 2007

Active Inhibitor-1 Maintains Protein Hyper-Phosphorylation in Aging Hearts and Halts Remodeling in Failing Hearts

por Pritchard, Tracy J., Kawase, Yoshiaki, Haghighi, Kobra, Anjak, Ahmad, Cai, Wenfeng, Jiang, Min, Nicolaou, Persoulla, Pylar, George, Karakikes, Ioannis, Rapti, Kleopatra, Rubinstein, Jack, Hajjar, Roger J., Kranias, Evangelia G.
Publicado 2013

Phosphorylation of Hsp20 Promotes Fibrotic Remodeling and Heart Failure

por Gardner, George T., Travers, Joshua G., Qian, Jiang, Liu, Guan-Sheng, Haghighi, Kobra, Robbins, Nathan, Jiang, Min, Li, Yutian, Fan, Guo-Chang, Rubinstein, Jack, Blaxall, Burns C., Kranias, Evangelia G.
Publicado 2019

Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response

por Chowdhury, Shamim A. K., Warren, Chad M., Simon, Jillian N., Ryba, David M., Batra, Ashley, Varga, Peter, Kranias, Evangelia G., Tardiff, Jil C., Solaro, R. John, Wolska, Beata M.
Publicado 2020

The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy

por Arvanitis, Demetrios A., Sanoudou, Despina, Kolokathis, Fotis, Vafiadaki, Elizabeth, Papalouka, Vasiliki, Kontrogianni-Konstantopoulos, Aikaterini, Theodorakis, George N., Paraskevaidis, Ioannis A., Adamopoulos, Stamatios, Dorn, Gerald W., Kremastinos, Dimitrios Th., Kranias, Evangelia G.
Publicado 2008

Determinants of Ca(2+) release restitution: Insights from genetically altered animals and mathematical modeling

por Cely-Ortiz, Alejandra, Felice, Juan I., Díaz-Zegarra, Leandro A., Valverde, Carlos A., Federico, Marilén, Palomeque, Julieta, Wehrens, Xander H.T., Kranias, Evangelia G., Aiello, Ernesto A., Lascano, Elena C., Negroni, Jorge A., Mattiazzi, Alicia
Publicado 2020

Abnormal Calcium Cycling and Cardiac Arrhythmias Associated With the Human Ser96Ala Genetic Variant of Histidine‐Rich Calcium‐Binding Protein

por Singh, Vivek P., Rubinstein, Jack, Arvanitis, Demetrios A., Ren, Xiaoping, Gao, Xiaoqian, Haghighi, Kobra, Gilbert, Mark, Iyer, Venkat R., Kim, Do Han, Cho, Chunghee, Jones, Keith, Lorenz, John N., Armstrong, Clara F., Wang, Hong‐Sheng, Gyorke, Sandor, Kranias, Evangelia G.
Publicado 2013