Attacking MALT1 for ABC-DLBCL therapy

por Krappmann, Daniel
Publicado 2012

Combining precision oncology and immunotherapy by targeting the MALT1 protease

por Mempel, Thorsten R, Krappmann, Daniel
Publicado 2022

BCL10 – Bridging CARDs to Immune Activation

por Gehring, Torben, Seeholzer, Thomas, Krappmann, Daniel
Publicado 2018

TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions

por O’Neill, Thomas J., Gewies, Andreas, Seeholzer, Thomas, Krappmann, Daniel
Publicado 2023

GSK3β modulates NF-κB activation and RelB degradation through site-specific phosphorylation of BCL10

por Abd-Ellah, Ali, Voogdt, Cornelia, Krappmann, Daniel, Möller, Peter, Marienfeld, Ralf B.
Publicado 2018

Combinatorial BTK and MALT1 inhibition augments killing of CD79 mutant diffuse large B cell lymphoma

por Nagel, Daniel, Bognar, Miriam, Eitelhuber, Andrea C., Kutzner, Kerstin, Vincendeau, Michelle, Krappmann, Daniel
Publicado 2015

AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation

por Schimmack, Gisela, Eitelhuber, Andrea C, Vincendeau, Michelle, Demski, Katrin, Shinohara, Hisaaki, Kurosaki, Tomohiro, Krappmann, Daniel
Publicado 2014

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB

por Schimmack, Gisela, Schorpp, Kenji, Kutzner, Kerstin, Gehring, Torben, Brenke, Jara Kerstin, Hadian, Kamyar, Krappmann, Daniel
Publicado 2017

Electrocatalytic Energy Release of Norbornadiene‐Based Molecular Solar Thermal Systems: Tuning the Electrochemical Stability by Molecular Design

por Franz, Evanie, Krappmann, Daniel, Fromm, Lukas, Luchs, Tobias, Görling, Andreas, Hirsch, Andreas, Brummel, Olaf, Libuda, Jörg
Publicado 2022

Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells

por Ferch, Uta, Kloo, Bernhard, Gewies, Andreas, Pfänder, Vera, Düwel, Michael, Peschel, Christian, Krappmann, Daniel, Ruland, Jürgen
Publicado 2009

Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells

por Ferch, Uta, Kloo, Bernhard, Gewies, Andreas, Pfänder, Vera, Düwel, Michael, Peschel, Christian, Krappmann, Daniel, Ruland, Jürgen
Publicado 2009

BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation

por Seeholzer, Thomas, Kurz, Susanne, Schlauderer, Florian, Woods, Simone, Gehring, Torben, Widmann, Simon, Lammens, Katja, Krappmann, Daniel
Publicado 2018

Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1

por Jones, Alisha N., Graß, Carina, Meininger, Isabel, Geerlof, Arie, Klostermann, Melina, Zarnack, Kathi, Krappmann, Daniel, Sattler, Michael
Publicado 2022

Molecular architecture and regulation of BCL10-MALT1 filaments

por Schlauderer, Florian, Seeholzer, Thomas, Desfosses, Ambroise, Gehring, Torben, Strauss, Mike, Hopfner, Karl-Peter, Gutsche, Irina, Krappmann, Daniel, Lammens, Katja
Publicado 2018

Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Trans...

por Hinz, Michael, Lemke, Petra, Anagnostopoulos, Ioannis, Hacker, Christine, Krappmann, Daniel, Mathas, Stephan, Dörken, Bernd, Zenke, Martin, Stein, Harald, Scheidereit, Claus
Publicado 2002

A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN

por Weber, Aurelia, Elliott, Paul R., Pinto-Fernandez, Adan, Bonham, Sarah, Kessler, Benedikt M., Komander, David, El Oualid, Farid, Krappmann, Daniel
Publicado 2017

A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells

por Yin, Hongli, Karayel, Ozge, Chao, Ying-Yin, Seeholzer, Thomas, Hamp, Isabel, Plettenburg, Oliver, Gehring, Torben, Zielinski, Christina, Mann, Matthias, Krappmann, Daniel
Publicado 2022

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

por Mc Guire, Conor, Elton, Lynn, Wieghofer, Peter, Staal, Jens, Voet, Sofie, Demeyer, Annelies, Nagel, Daniel, Krappmann, Daniel, Prinz, Marco, Beyaert, Rudi, van Loo, Geert
Publicado 2014

Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

por Van Campenhout, Claude A., Eitelhuber, Andrea, Gloeckner, Christian J., Giallonardo, Patrizia, Gegg, Moritz, Oller, Heide, Grant, Seth G.N., Krappmann, Daniel, Ueffing, Marius, Lickert, Heiko
Publicado 2011

Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant

por Kutukculer, Necil, Seeholzer, Thomas, O’Neill, Thomas J., Graß, Carina, Aykut, Ayca, Karaca, Neslihan Edeer, Durmaz, Asude, Cogulu, Ozgur, Aksu, Guzide, Gehring, Torben, Gewies, Andreas, Krappmann, Daniel
Publicado 2021