Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies

por Easton, Amy, Jensen, Marianne L., Wang, Congwei, Hagedorn, Peter H., Li, Yuwen, Weed, Michael, Meredith, Jere E., Guss, Valerie, Jones, Kelli, Gill, Martin, Krause, Carol, Brown, Jeffrey M., Hunihan, Lisa, Natale, Joanne, Fernandes, Alda, Lu, Yifeng, Polino, Joe, Bookbinder, Mark, Cadelina, Greg, Benitex, Yulia, Sane, Ramola, Morrison, John, Drexler, Dieter, Mercer, Stephen E., Bon, Charlotte, Pandya, Nikhil J., Jagasia, Ravi, Ou Yang, Tai-Hsien, Distler, Tania, Grüninger, Fiona, Meldgaard, Michael, Terrigno, Marco, Macor, John E., Albright, Charles F., Loy, James, Hoeg, Anja M., Olson, Richard E., Cacace, Angela M.
Publicado 2022

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780

por Toyn, Jeremy H., Thompson, Lorin A., Lentz, Kimberley A., Meredith, Jere E., Burton, Catherine R., Sankaranararyanan, Sethu, Guss, Valerie, Hall, Tracey, Iben, Lawrence G., Krause, Carol M., Krause, Rudy, Lin, Xu-Alan, Pierdomenico, Maria, Polson, Craig, Robertson, Alan S., Denton, R. Rex, Grace, James E., Morrison, John, Raybon, Joseph, Zhuo, Xiaoliang, Snow, Kimberly, Padmanabha, Ramesh, Agler, Michele, Esposito, Kim, Harden, David, Prack, Margaret, Varma, Sam, Wong, Victoria, Zhu, Yingjie, Zvyaga, Tatyana, Gerritz, Samuel, Marcin, Lawrence R., Higgins, Mendi A., Shi, Jianliang, Wei, Cong, Cantone, Joseph L., Drexler, Dieter M., Macor, John E., Olson, Richard E., Ahlijanian, Michael K., Albright, Charles F.
Publicado 2014