Plazomicin Is Active Against Metallo-β-Lactamase-Producing Enterobacteriaceae

por Serio, Alisa W, Keepers, Tiffany, Krause, Kevin M
Publicado 2019

A Broken Antibiotic Market: Review of Strategies to Incentivize Drug Development

por Bhavnani, Sujata M, Krause, Kevin M, Ambrose, Paul G
Publicado 2020

Assessment of the In Vivo Efficacy of Plazomicin (PLZ) Alone or in Combination with Meropenem (MEM) or Tigecycline (TGC) against Enterobacteriaceae (EB) Isolates Exhibiting Various...

por Abdelraouf, Kamilia, Kim, Aryun, Krause, Kevin M, Nicolau, David P
Publicado 2017

Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria

por Asli, Abdelhamid, Brouillette, Eric, Krause, Kevin M., Nichols, Wright W., Malouin, François
Publicado 2016

Effect of In Vitro Testing Parameters on Ceftazidime-Avibactam Minimum Inhibitory Concentrations

por Keepers, Tiffany R., Gomez, Marcela, Biek, Donald, Critchley, Ian, Krause, Kevin M.
Publicado 2015

Fosfomycin and Comparator Activity Against Select Enterobacteriaceae, Pseudomonas, and Enterococcus Urinary Tract Infection Isolates from the United States in 2012

por Keepers, Tiffany R., Gomez, Marcela, Celeri, Chris, Krause, Kevin M., Biek, Donald, Critchley, Ian
Publicado 2017

1345. Comparative Activity of Plazomicin and Other Aminoglycosides Against Enterobacteriaceae Isolates From Various Infection Sources From Hospitalized Patients in the United State...

por Castanheira, Mariana, Streit, Jennifer M, Serio, Alisa W, Krause, Kevin M, Flamm, Robert K
Publicado 2018

1964. Microbiological Outcomes With Plazomicin (PLZ) vs. Colistin (CST) in Patients With Bloodstream Infections (BSI) Caused by Carbapenem-Resistant Enterobacteriaceae (CRE) in the...

por Serio, Alisa W, Smith, Alex, Krause, Kevin M, Galani, Irene, Gales, Ana Cristina, Jubb, Adrian, Connolly, Lynn E
Publicado 2018

Activity of Plazomicin against Enterobacteriaceae Isolates Collected in the United States Including Isolates Carrying Aminoglycoside-Modifying Enzymes Detected by Whole Genome Sequ...

por Castanheira, Mariana, Deshpande, Lalitagauri M, Hubler, Cory M, Mendes, Rodrigo E, Serio, Alisa W, Krause, Kevin M, Flamm, Robert K
Publicado 2017

593. Population Pharmacokinetic Model Development for Epetraborole and Mycobacterium avium Complex (MAC) Lung Disease Patients Using Data from Phase 1 and 2 Studies

por Ganesan, Harish, Courtney Safir, M, Bhavnani, Sujata M, Bhavnani, Sujata M, Bhavnani, Sujata M, Krause, Kevin M, Rubino, Christopher M
Publicado 2022

1727. Phase 1b Dose-ranging Study Demonstrates Tolerability and Pharmacokinetics (PK) of Oral Epetraborole at the Predicted Therapeutic Dosage for Mycobacterium avium Complex (MAC)...

por Eckburg, Paul B, Clarke, Dave, Long, Jennifer, Chanda, Sanjay, Krause, Kevin M, Easom, Eric, Talbot, George, Rubino, Christopher M, Molga, Angela
Publicado 2022

2556. A Phase 1, Open-Label, Single Dose Study to Evaluate the Pharmacokinetics (PK), Safety, and Tolerability of Epetraborole Tablets and the Impact of Alcohol Dehydrogenase (ADH)...

por Patel, Gina, Castañeda-Ruiz, Bibiana, Yoshihara, Tatsuya, Krause, Kevin M, O’Shea, Kevin, Kammerer, Linda, Maier, Gary, Long, Jennifer, Smith, Alex, Chanda, Sanjay, Moore, Stephanie, Eckburg, Paul B
Publicado 2023

1348. In vitro Activity of Plazomicin, a Next-Generation Aminoglycoside, Against Carbapenemase-Producing Klebsiella pneumoniae

por Jacobs, Michael R, Good, Caryn E, Abdelhamed, Ayman M, Rhoads, Daniel D, Hujer, Kristine M, Hujer, Andrea M, Rudin, Susan D, Domitrovic, T Nicholas, Connolly, Lynn, Krause, Kevin M, Richter, Sandra S, Van Duin, David, Kreiswirth, Barry N, Bonomo, Robert A
Publicado 2018