Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

por Alikhanyan, Kristina, Chen, Yuanyuan, Kraut, Simone, Sotillo, Rocio
Publicado 2020

Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment

por Alikhanyan, Kristina, Chen, Yuanyuan, Somogyi, Kalman, Kraut, Simone, Sotillo, Rocio
Publicado 2021

Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease

por Neves, Joana, Leitz, Dominik, Kraut, Simone, Brandenberger, Christina, Agrawal, Raman, Weissmann, Norbert, Mühlfeld, Christian, Mall, Marcus A., Altamura, Sandro, Muckenthaler, Martina U.
Publicado 2017

Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice

por Malkmus, Kathrin, Brosien, Monika, Knoepp, Fenja, Schaffelhofer, Lisa, Grimminger, Friedrich, Rummel, Christoph, Gudermann, Thomas, Dietrich, Alexander, Birnbaumer, Lutz, Weissmann, Norbert, Kraut, Simone
Publicado 2022

iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice

por Gredic, Marija, Sharma, Vinita, Hadzic, Stefan, Wu, Cheng-Yu, Pak, Oleg, Kojonazarov, Baktybek, Duerr, Julia, Mall, Marcus A., Guenther, Andreas, Schermuly, Ralph T., Grimminger, Friedrich, Seeger, Werner, Kraut, Simone, Sommer, Natascha, Weissmann, Norbert
Publicado 2022

Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice

por Gredic, Marija, Wu, Cheng-Yu, Hadzic, Stefan, Pak, Oleg, Savai, Rajkumar, Kojonazarov, Baktybek, Doswada, Siddartha, Weiss, Astrid, Weigert, Andreas, Guenther, Andreas, Brandes, Ralf P., Schermuly, Ralph T., Grimminger, Friedrich, Seeger, Werner, Sommer, Natascha, Kraut, Simone, Weissmann, Norbert
Publicado 2022

FGF10 Triggers De Novo Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells

por Taghizadeh, Sara, Chao, Cho-Ming, Guenther, Stefan, Glaser, Lea, Gersmann, Luisa, Michel, Gabriela, Kraut, Simone, Goth, Kerstin, Koepke, Janine, Heiner, Monika, Vazquez-Armendariz, Ana Ivonne, Herold, Susanne, Samakovlis, Christos, Weissmann, Norbert, Ricci, Francesca, Aquila, Giorgio, Boyer, Laurent, Ehrhardt, Harald, Minoo, Parviz, Bellusci, Saverio, Rivetti, Stefano
Publicado 2022

Decreased plasma levels of the brain-derived neurotrophic factor correlate with right heart congestion in pulmonary arterial hypertension

por Schäfer, Katharina, Tello, Khodr, Pak, Oleg, Richter, Manuel, Gierhardt, Mareike, Kwapiszewska, Grazyna, Veith, Christine, Fink, Ludger, Gall, Henning, Hecker, Matthias, Kojonazarov, Baktybek, Kraut, Simone, Lo, Kevin, Wilhelm, Jochen, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph T., Ghofrani, Hossein A., Zahner, Daniel, Gerstberger, Rüdiger, Weissmann, Norbert, Sydykov, Akylbek, Sommer, Natascha
Publicado 2023

Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice

por Hadzic, Stefan, Wu, Cheng-Yu, Gredic, Marija, Pak, Oleg, Loku, Edma, Kraut, Simone, Kojonazarov, Baktybek, Wilhelm, Jochen, Brosien, Monika, Bednorz, Mariola, Seimetz, Michael, Günther, Andreas, Kosanovic, Djuro, Sommer, Natascha, Warburton, David, Li, Xiaokun, Grimminger, Friedrich, Ghofrani, Hossein A., Schermuly, Ralph T., Seeger, Werner, El Agha, Elie, Bellusci, Saverio, Weissmann, Norbert
Publicado 2023

Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing

por Sommer, Natascha, Alebrahimdehkordi, Nasim, Pak, Oleg, Knoepp, Fenja, Strielkov, Ievgen, Scheibe, Susan, Dufour, Eric, Andjelković, Ana, Sydykov, Akylbek, Saraji, Alireza, Petrovic, Aleksandar, Quanz, Karin, Hecker, Matthias, Kumar, Manish, Wahl, Joel, Kraut, Simone, Seeger, Werner, Schermuly, Ralph T., Ghofrani, Hossein A., Ramser, Kerstin, Braun, Thomas, Jacobs, Howard T., Weissmann, Norbert, Szibor, Marten
Publicado 2020

Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone

por Gierhardt, Mareike, Pak, Oleg, Sydykov, Akylbek, Kraut, Simone, Schäffer, Julia, Garcia, Claudia, Veith, Christine, Zeidan, Esraa M, Brosien, Monika, Quanz, Karin, Esfandiary, Azadeh, Saraji, Alireza, Hadzic, Stefan, Kojonazarov, Baktybek, Wilhelm, Jochen, Ghofrani, Hossein A, Schermuly, Ralph T, Seeger, Werner, Grimminger, Friedrich, Herden, Christiane, Schulz, Rainer, Weissmann, Norbert, Heger, Jacqueline, Sommer, Natascha
Publicado 2020

Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations

por Roxlau, Elsa T., Pak, Oleg, Hadzic, Stefan, Garcia-Castro, Claudia F., Gredic, Marija, Wu, Cheng-Yu, Schäffer, Julia, Selvakumar, Balachandar, Pichl, Alexandra, Spiegelberg, David, Deutscher, Janik, Bednorz, Mariola, Schäfer, Katharina, Kraut, Simone, Kosanovic, Djuro, Zeidan, Esraa M., Kojonazarov, Baktybek, Herold, Susanne, Strielkov, Ievgen, Guenther, Andreas, Wilhelm, Jochen, Khalifa, Mohamed M.A., Taye, Ashraf, Brandes, Ralf P., Hecker, Matthias, Grimminger, Friedrich, Ghofrani, Hossein A., Schermuly, Ralph T., Seeger, Werner, Sommer, Natascha, Weissmann, Norbert
Publicado 2023