Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects

por Krečmerová, Marcela, Majer, Pavel, Rais, Rana, Slusher, Barbara S.
Publicado 2022

Lipases as Tools in the Synthesis of Prodrugs from Racemic 9-(2,3-Dihydroxypropyl)adenine

por Brabcová, Jana, Blažek, Jiří, Janská, Lucie, Krečmerová, Marcela, Zarevúcka, Marie
Publicado 2012

Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety

por Pomeisl, Karel, Krečmerová, Marcela, Pohl, Radek, Snoeck, Robert, Andrei, Graciela
Publicado 2019

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety

por Tichý, Tomáš, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Dračínský, Martin, Krečmerová, Marcela
Publicado 2012

New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity

por Krečmerová, Marcela, Dračínský, Martin, Snoeck, Robert, Balzarini, Jan, Pomeisl, Karel, Andrei, Graciela
Publicado 2017

Phosphofructokinases A and B from Mycobacterium tuberculosis Display Different Catalytic Properties and Allosteric Regulation

por Snášel, Jan, Machová, Iva, Šolínová, Veronika, Kašička, Václav, Krečmerová, Marcela, Pichová, Iva
Publicado 2021

Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance

por Andrei, Graciela, Fiten, Pierre, Krečmerová, Marcela, Opdenakker, Ghislain, Topalis, Dimitrios, Snoeck, Robert
Publicado 2022

Regioselective Palmitoylation of 9-(2,3-Dihydroxy- propyl)adenine Catalyzed by a Glycopolymer-enzyme Conjugate

por Brabcová, Jana, Blažek, Jiří, Krečmerová, Marcela, Vondrášek, Jiří, Palomo, Jose M., Zarevúcka, Marie
Publicado 2016

New prodrugs of Adefovir and Cidofovir

por Tichý, Tomáš, Andrei, Graciela, Dračínský, Martin, Holý, Antonín, Balzarini, Jan, Snoeck, Robert, Krečmerová, Marcela
Publicado 2011

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

por Topalis, Dimitri, Nogueira, Tatiane C., De Schutter, Tim, El Amri, Chahrazade, Krečmerová, Marcela, Naesens, Lieve, Balzarini, Jan, Andrei, Graciela, Snoeck, Robert
Publicado 2016

9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in...

por Krečmerová, Marcela, Jansa, Petr, Dračínský, Martin, Sázelová, Petra, Kašička, Václav, Neyts, Johan, Auwerx, Joeri, Kiss, Eleonóra, Goris, Nesya, Stepan, George, Janeba, Zlatko
Publicado 2013

Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor

por Lemberg, Kathryn M., Ali, Eunus S., Krecmerova, Marcela, Aguilar, Joanna Marie H., Alt, Jesse, Peters, Diane E., Zhao, Liang, Wu, Ying, Nuha, Naziba, Asara, John M., Staedtke, Verena, Pratilas, Christine A., Majer, Pavel, Rais, Rana, Ben-Sahra, Issam, Slusher, Barbara S.
Publicado 2023