A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics

por Lee, Ho-Joon, Kremer, Daniel M., Sajjakulnukit, Peter, Zhang, Li, Lyssiotis, Costas A.
Publicado 2019

Hyaluronic acid fuels pancreatic cancer cell growth

por Kim, Peter K, Halbrook, Christopher J, Kerk, Samuel A, Radyk, Megan, Wisner, Stephanie, Kremer, Daniel M, Sajjakulnukit, Peter, Andren, Anthony, Hou, Sean W, Trivedi, Ayush, Thurston, Galloway, Anand, Abhinav, Yan, Liang, Salamanca-Cardona, Lucia, Welling, Samuel D, Zhang, Li, Pratt, Matthew R, Keshari, Kayvan R, Ying, Haoqiang, Lyssiotis, Costas A
Publicado 2021

Mutant p53(R270H) drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma

por Schofield, Heather K., Zeller, Jörg, Espinoza, Carlos, Halbrook, Christopher J., del Vecchio, Annachiara, Magnuson, Brian, Fabo, Tania, Daylan, Ayse Ece Cali, Kovalenko, Ilya, Lee, Ho-Joon, Yan, Wei, Feng, Ying, Karim, Saadia A., Kremer, Daniel M., Kumar-Sinha, Chandan, Lyssiotis, Costas A., Ljungman, Mats, Morton, Jennifer P., Galbán, Stefanie, Fearon, Eric R., Pasca di Magliano, Marina
Publicado 2018

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

por Nelson, Barbara S., Lin, Lin, Kremer, Daniel M., Sousa, Cristovão M., Cotta-Ramusino, Cecilia, Myers, Amy, Ramos, Johanna, Gao, Tina, Kovalenko, Ilya, Wilder-Romans, Kari, Dresser, Joseph, Davis, Mary, Lee, Ho-Joon, Nwosu, Zeribe C., Campit, Scott, Mashadova, Oksana, Nicolay, Brandon N., Tolstyka, Zachary P., Halbrook, Christopher J., Chandrasekaran, Sriram, Asara, John M., Crawford, Howard C., Cantley, Lewis C., Kimmelman, Alec C., Wahl, Daniel R., Lyssiotis, Costas A.
Publicado 2020

Cancer SLC43A2 alters T cell methionine metabolism and histone methylation

por Bian, Yingjie, Li, Wei, Kremer, Daniel M., Sajjakulnukit, Peter, Li, Shasha, Crespo, Joel, Nwosu, Zeribe C., Zhang, Li, Czerwonka, Arkadiusz, Pawłowska, Anna, Xia, Houjun, Li, Jing, Liao, Peng, Yu, Jiali, Vatan, Linda, Szeliga, Wojciech, Wei, Shuang, Grove, Sara, Liu, J. Rebecca, McLean, Karen, Cieslik, Marcin, Chinnaiyan, Arul M., Zgodziński, Witold, Wallner, Grzegorz, Wertel, Iwona, Okła, Karolina, Kryczek, Ilona, Lyssiotis, Costas A., Zou, Weiping
Publicado 2020

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

por Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.
Publicado 2021