Cyclin-Dependent Kinase and Antioxidant Gene Expression in Cancers with Poor Therapeutic Response

por Scaria, George S., Kren, Betsy T., Klein, Mark A.
Publicado 2020

Inhibition of Mitochondrial Antioxidant Defense and CDK4/6 in Mesothelioma

por Kratzke, Marian, Scaria, George, Porter, Stephen, Kren, Betsy, Klein, Mark A.
Publicado 2023

Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

por Trembley, Janeen H., Kren, Betsy T., Afzal, Muhammad, Scaria, George A., Klein, Mark A., Ahmed, Khalil
Publicado 2022

Immune characteristics correlating with HSV‐1 immune control and effect of squaric acid dibutyl ester on immune characteristics of subjects with frequent herpes labialis episodes

por McTavish, Hugh, Zerebiec, Katherine W., Zeller, Jay C., Shekels, Laurie L., Matson, Mark A., Kren, Betsy T.
Publicado 2019

CK2 Pro-Survival Role in Prostate Cancer Is Mediated via Maintenance and Promotion of Androgen Receptor and NFκB p65 Expression

por Trembley, Janeen H., Kren, Betsy T., Abedin, Md. J., Shaughnessy, Daniel P., Li, Yingming, Dehm, Scott M., Ahmed, Khalil
Publicado 2019

CX-4945 and siRNA-Mediated Knockdown of CK2 Improves Cisplatin Response in HPV(+) and HPV(−) HNSCC Cell Lines

por Trembley, Janeen H., Li, Bin, Kren, Betsy T., Gravely, Amy A., Caicedo-Granados, Emiro, Klein, Mark A., Ahmed, Khalil
Publicado 2021

Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

por Kren, Betsy T, Unger, Gretchen M, Abedin, Md J, Vogel, Rachel I, Henzler, Christine M, Ahmed, Khalil, Trembley, Janeen H
Publicado 2015

CK2 Molecular Targeting—Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

por Trembley, Janeen H., Kren, Betsy T., Abedin, Md. Joynal, Vogel, Rachel I., Cannon, Claire M., Unger, Gretchen M., Ahmed, Khalil
Publicado 2017

CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells

por Ahmed, Rehana L., Shaughnessy, Daniel P., Knutson, Todd P., Vogel, Rachel I., Ahmed, Khalil, Kren, Betsy T., Trembley, Janeen H.
Publicado 2019

Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes

por Trembley, Janeen H., Li, Bin, Kren, Betsy T., Peltola, Justin, Manivel, Juan, Meyyappan, Devi, Gravely, Amy, Klein, Mark, Ahmed, Khalil, Caicedo-Granados, Emiro
Publicado 2021

Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice

por Trembley, Janeen H., Unger, Gretchen M., Korman, Vicci L., Abedin, Md. Joynal, Nacusi, Lucas P., Vogel, Rachel I., Slaton, Joel W., Kren, Betsy T., Ahmed, Khalil
Publicado 2014

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

por Wu, Heng, Kren, Betsy T., Lane, Andrew N., Cassel, Teresa A., Higashi, Richard M., Fan, Teresa W.M., Scaria, George S., Shekels, Laurie L., Klein, Mark A., Albrecht, Jeffrey H.
Publicado 2023

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors

por Ahmed, Khalil, Kren, Betsy T., Abedin, Md. Joynal, Vogel, Rachel I., Shaughnessy, Daniel P., Nacusi, Lucas, Korman, Vicci L., Li, Yingming, Dehm, Scott M., Zimmerman, Cheryl L., Niehans, Gloria A., Unger, Gretchen M., Trembley, Janeen H.
Publicado 2016

Evaluation of a new high-dimensional miRNA profiling platform

por Cunningham, Julie M, Oberg, Ann L, Borralho, Pedro M, Kren, Betsy T, French, Amy J, Wang, Liang, Bot, Brian M, Morlan, Bruce W, Silverstein, Kevin AT, Staggs, Rod, Zeng, Yan, Lamblin, Anne-Francoise, Hilker, Christopher A, Fan, Jian-Bing, Steer, Clifford J, Thibodeau, Stephen N
Publicado 2009