Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond

por Kresbach, Catena, Neyazi, Sina, Schüller, Ulrich
Publicado 2022

MEDB-11. MYC overexpression and SMARCA4 loss in cerebellar granule cell precursors cooperate to drive medulloblastoma formation in mice

por Göbel, Carolin, Holdhof, Dörthe, Schoof, Melanie, Kresbach, Catena, Schüller, Ulrich
Publicado 2022

Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling

por Kresbach, Catena, Bronsema, Annika, Guerreiro, Helena, Rutkowski, Stefan, Schüller, Ulrich, Winkler, Beate
Publicado 2021

Malignant gliomas with H3F3A G34R mutation or MYCN amplification in pediatric patients with Li Fraumeni syndrome

por Schoof, Melanie, Kordes, Uwe, Volk, Alexander E., Al-Kershi, Sina, Kresbach, Catena, Schüller, Ulrich
Publicado 2021

MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

por Göbel, Carolin, Godbole, Shweta, Schoof, Melanie, Holdhof, Dörthe, Kresbach, Catena, Loose, Carolin, Neumann, Julia, Schüller, Ulrich
Publicado 2023

MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma

por Kresbach, Catena, Schoof, Melanie, Holst, Lea, Leven, Tara, Yorgan, Timur, Wrzeszcz, Antonina, Rutkowski, Stefan, Schüller, Ulrich
Publicado 2022

Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of t...

por Bremmer, Felix, Pongratanakul, Pailin, Skowron, Margaretha, Che, Yue, Richter, Annika, Küffer, Stefan, Reuter-Jessen, Kirsten, Bohnenberger, Hanibal, Pauls, Stella, Kresbach, Catena, Schüller, Ulrich, Stühler, Kai, Ströbel, Philipp, Albers, Peter, Nettersheim, Daniel
Publicado 2023

Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype

por Kresbach, Catena, Dorostkar, Mario M., Suwala, Abigail K., Wefers, Annika K., Schweizer, Leonille, Engertsberger, Lara, Bison, Brigitte, Mynarek, Martin, Kloth-Stachnau, Katja, Spohn, Michael, von Deimling, Andreas, Benesch, Martin, Hagel, Christian, Mautner, Viktor-F., Rutkowski, Stefan, Schüller, Ulrich
Publicado 2021

HGG-15. Generation of a novel mouse model for brain tumors of the DNA methylation class “GBM MYCN”

por Schoof, Melanie, Godbole, Shweta, Walter, Carolin, Dottermusch, Matthias, Albert, Thomas, Ballast, Annika, Göbel, Carolin, Neyazi, Sina, Holdhof, Dörthe, Kresbach, Catena, Blattner-Johnson, Mirjam, Modemann, Franziska, Afflerbach, Ann-Kristin, Eckhardt, Alicia, Struve, Nina, Jones, David, Kerl, Kornelius, Neumann, Julia E, Schüller, Ulrich
Publicado 2022

Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics

por Johann, Pascal D., Altendorf, Lea, Efremova, Emma-Maria, Holsten, Till, Steinbügl, Mona, Nemes, Karolina, Eckhardt, Alicia, Kresbach, Catena, Bockmayr, Michael, Koch, Arend, Haberler, Christine, Antonelli, Manila, DeSisto, John, Schuhmann, Martin U., Hauser, Peter, Siebert, Reiner, Bens, Susanne, Kool, Marcel, Green, Adam L., Hasselblatt, Martin, Frühwald, Michael C., Schüller, Ulrich
Publicado 2023

BIOL-10. MOUSE MODELING OF PEDIATRIC MYCN GLIOMA REVEALS INTRATUMORAL HETEROGENEITY INCLUDING NEURONAL AND OLIGODENDROGLIAL LINEAGE SIGNATURES

por Schoof, Melanie, Godbole, Shweta, Albert, Thomas K, Dottermusch, Matthias, Walter, Carolin, Ballast, Annika, Qin, Nan, Olivera, Marlene Baca, Göbel, Carolin, Neyazi, Sina, Holdhof, Dörthe, Kresbach, Catena, Epplen, Gefion Dorothea, Thaden, Vanessa, Blattner-Johnson, Mirjam, Modemann, Franziska, Afflerbach, Ann-Kristin, Eckhardt, Alicia, Muenter, Daniel, Struve, Nina, Jones, David T W, Remke, Marc, Neumann, Julia E, Kerl, Kornelius, Schüller, Ulrich
Publicado 2023

Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

por Schoof, Melanie, Godbole, Shweta, Albert, Thomas K., Dottermusch, Matthias, Walter, Carolin, Ballast, Annika, Qin, Nan, Olivera, Marlena Baca, Göbel, Carolin, Neyazi, Sina, Holdhof, Dörthe, Kresbach, Catena, Peter, Levke-Sophie, Epplen, Gefion Dorothea, Thaden, Vanessa, Spohn, Michael, Blattner-Johnson, Mirjam, Modemann, Franziska, Mynarek, Martin, Rutkowski, Stefan, Sill, Martin, Varghese, Julian, Afflerbach, Ann-Kristin, Eckhardt, Alicia, Münter, Daniel, Verma, Archana, Struve, Nina, Jones, David T. W., Remke, Marc, Neumann, Julia E., Kerl, Kornelius, Schüller, Ulrich
Publicado 2023

EPEN-27. Epigenetic dissection of spinal ependymomas (SP-EPN) separates tumors with and withoutNF2 mutation

por Neyazi, Sina, Yamazawa, Erika, Kresbach, Catena, Nagae, Genta, Eckhardt, Alicia, Umeda, Takayoshi, Pohl, Lara, Tatsuno, Kenji, Saygi, Ceren, Hana, Taijun, Alawi, Malik, Kim, Phyo, Dorostkar, Mario M, Higuchi, Fumi, Suwala, Abigail K, Takami, Toshihiro, Wefers, Annika, Nakanishi, Yuta, Schweizer, Leonille, Takai, Keisuke, Engertsberger, Lara, Komori, Takashi, Mohme, Theresa, Takami, Hirokazu, Mynarek, Martin, Nomura, Masashi, Lamszus, Karin, Mukasa, Akitake, Kluwe, Lan, Takayanagi, Shunsaku, von Deimling, Andreas, Ishii, Kazuhiko, Benesch, Martin, Imai, Hideaki, Snuderl, Matija, Frank, Stephan, Ichimura, Koichi, Hagel, Christian, Mautner, Viktor F, Rutkowski, Stefan, Tanaka, Shota, Aburatani, Hiroyuki, Nobuhito, Saito, Schüller, Ulrich
Publicado 2022