The failure of cetuximab-based de-intensified regimes for HPV-positive OPSCC: A radiobiologists perspective

por Rieckmann, Thorsten, Kriegs, Malte
Publicado 2019

Improving the Efficacy of Tumor Radiosensitization Through Combined Molecular Targeting

por Hintelmann, Katharina, Kriegs, Malte, Rothkamm, Kai, Rieckmann, Thorsten
Publicado 2020

Analyzing the influence of kinase inhibitors on DNA repair by differential proteomics of chromatin-interacting proteins and nuclear phospho-proteins

por Gleißner, Lisa, Kwiatkowski, Marcel, Myllynen, Laura, Steffen, Pascal, Petersen, Cordula, Rothkamm, Kai, Schlüter, Hartmut, Kriegs, Malte
Publicado 2017

Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib

por Heintze, Linda, Schmidt, Dorian, Rodat, Theo, Witt, Lydia, Ewert, Julia, Kriegs, Malte, Herges, Rainer, Peifer, Christian
Publicado 2020

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

por Riedel, Matthias, Struve, Nina, Müller-Goebel, Justus, Köcher, Sabrina, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai, Kriegs, Malte
Publicado 2016

A Subset of Histone H2B Genes Produces Polyadenylated mRNAs under a Variety of Cellular Conditions

por Kari, Vijayalakshmi, Karpiuk, Oleksandra, Tieg, Bettina, Kriegs, Malte, Dikomey, Ekkehard, Krebber, Heike, Begus-Nahrmann, Yvonne, Johnsen, Steven A.
Publicado 2013

SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

por Ehm, Patrick, Rietow, Ruth, Wegner, Wiebke, Bußmann, Lara, Kriegs, Malte, Dierck, Kevin, Horn, Stefan, Streichert, Thomas, Horstmann, Martin, Jücker, Manfred
Publicado 2023

Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma

por Braig, Friederike, Voigtlaender, Minna, Schieferdecker, Aneta, Busch, Chia-Jung, Laban, Simon, Grob, Tobias, Kriegs, Malte, Knecht, Rainald, Bokemeyer, Carsten, Binder, Mascha
Publicado 2016

Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis

por Hinz, Nico, Baranowsky, Anke, Horn, Michael, Kriegs, Malte, Sibbertsen, Freya, Smit, Daniel J., Clezardin, Philippe, Lange, Tobias, Schinke, Thorsten, Jücker, Manfred
Publicado 2021

Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells

por Hintelmann, Katharina, Berenz, Thomas, Kriegs, Malte, Christiansen, Sabrina, Gatzemeier, Fruzsina, Struve, Nina, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Oetting, Agnes, Rieckmann, Thorsten
Publicado 2021

EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

por Struve, Nina, Riedel, Matthias, Schulte, Alexander, Rieckmann, Thorsten, Grob, Tobias J., Gal, Andreas, Rothkamm, Kai, Lamszus, Katrin, Petersen, Cordula, Dikomey, Ekkehard, Kriegs, Malte
Publicado 2015

Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines

por Busch, Chia-Jung, Becker, Benjamin, Kriegs, Malte, Gatzemeier, Fruzsina, Krüger, Katharina, Möckelmann, Nikolaus, Fritz, Gerhard, Petersen, Cordula, Knecht, Rainald, Rothkamm, Kai, Rieckmann, Thorsten
Publicado 2016

Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells

por Dyshlovoy, Sergey A., Busenbender, Tobias, Hauschild, Jessica, Girich, Elena V., Kriegs, Malte, Hoffer, Konstantin, Graefen, Markus, Yurchenko, Anton N., Bokemeyer, Carsten, von Amsberg, Gunhild
Publicado 2022

Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy

por Viol, Fabrice, Sipos, Bence, Fahl, Martina, Clauditz, Till S., Amin, Tania, Kriegs, Malte, Nieser, Maike, Izbicki, Jakob R., Huber, Samuel, Lohse, Ansgar W., Schrader, Jörg
Publicado 2022

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

por Mund, Andreas, Schubert, Tobias, Staege, Hannah, Kinkley, Sarah, Reumann, Kerstin, Kriegs, Malte, Fritsch, Lauriane, Battisti, Valentine, Ait-Si-Ali, Slimane, Hoffbeck, Anne-Sophie, Soutoglou, Evi, Will, Hans
Publicado 2012

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

por Mund, Andreas, Schubert, Tobias, Staege, Hannah, Kinkley, Sarah, Reumann, Kerstin, Kriegs, Malte, Fritsch, Lauriane, Battisti, Valentine, Ait-Si-Ali, Slimane, Hoffbeck, Anne-Sophie, Soutoglou, Evi, Will, Hans
Publicado 2020

Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

por Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Publicado 2016

Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling

por Tintelnot, Joseph, Metz, Sina, Trentmann, Marie, Oberle, Anna, von Wenserski, Lisa, Schultheiß, Christoph, Braig, Friederike, Kriegs, Malte, Fehse, Boris, Riecken, Kristoffer, Bokemeyer, Carsten, Stein, Alexander, Binder, Mascha
Publicado 2020

Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties

por Dyshlovoy, Sergey A., Kaune, Moritz, Kriegs, Malte, Hauschild, Jessica, Busenbender, Tobias, Shubina, Larisa K., Makarieva, Tatyana N., Hoffer, Konstantin, Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Publicado 2020

G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

por Cetin, Meryem H., Rieckmann, Thorsten, Hoffer, Konstantin, Riepen, Britta, Christiansen, Sabrina, Gatzemeier, Fruzsina, Feyerabend, Simon, Schoof, Melanie, Schüller, Ulrich, Petersen, Cordula, Mynarek, Martin, Rothkamm, Kai, Kriegs, Malte, Struve, Nina
Publicado 2023