Non-motor parkinsonian pathology in aging A53T α-Synuclein mice is associated with progressive synucleinopathy and altered enzymatic function

por Farrell, Kaitlin F, Krishnamachari, Sesha, Villanueva, Ernesto, Lou, Haiyan, Alerte, Tshianda N M, Peet, Eloise, Drolet, Robert E, Perez, Ruth G
Publicado 2014

Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation

por Bowroju, Suresh K., Mainali, Nirjal, Ayyadevara, Srinivas, Penthala, Narsimha R., Krishnamachari, Sesha, Kakraba, Samuel, Reis, Robert J. Shmookler, Crooks, Peter A.
Publicado 2020

Preclinical Metabolism, Pharmacokinetics and In Vivo Analysis of New Blood-Brain-Barrier Penetrant Fingolimod Analogues: FTY720-C2 and FTY720-Mitoxy

por Enoru, Julius O., Yang, Barbara, Krishnamachari, Sesha, Villanueva, Ernesto, DeMaio, William, Watanyar, Adiba, Chinnasamy, Ramesh, Arterburn, Jeffrey B., Perez, Ruth G.
Publicado 2016

Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer’s Disease

por Lilek, Jaclyn, Ajroud, Kaouther, Feldman, Alexander Z., Krishnamachari, Sesha, Ghourchian, Shadi, Gefen, Tamar, Spencer, Callen L., Kawles, Allegra, Mao, Qinwen, Tranovich, Jessica F., Jack, Clifford R., Mesulam, M-Marsel, Reichard, R. Ross, Zhang, Hui, Murray, Melissa E., Knopman, David, Dickson, Dennis W., Petersen, Ronald C., Smith, Benjamin, Ashe, Karen H., Mielke, Michelle M., Nelson, Kathryn M., Flanagan, Margaret E.
Publicado 2023