Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models

por Selvarasu, Karthikeyan, Singh, Abhay Kumar, Iyaswamy, Ashok, Gopalkrishnashetty Sreenivasmurthy, Sravan, Krishnamoorthi, Senthilkumar, Bera, Amal Kanti, Huang, Jian-Dong, Durairajan, Siva Sundara Kumar
Publicado 2022

Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease

por Wang, Xueli, Iyaswamy, Ashok, Xu, Di, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Yang, Yuncong, Li, Yinhui, Chen, Chen, Li, Min, Li, Hung-Wing, Wong, Man Shing
Publicado 2022

Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease

por Zhu, Zhou, Yang, Chuanbin, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Sreenivasmurthy, Sravan Gopalkrishnashetty, Liu, Jia, Wang, Ziying, Tong, Benjamin Chun-Kit, Song, Juxian, Lu, Jiahong, Cheung, King-Ho, Li, Min
Publicado 2019

Klotho an Autophagy Stimulator as a Potential Therapeutic Target for Alzheimer’s Disease: A Review

por Fung, Tsz Yan, Iyaswamy, Ashok, Sreenivasmurthy, Sravan G., Krishnamoorthi, Senthilkumar, Guan, Xin-Jie, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Kan, Yuxuan, Zhang, Yuan, Wong, Hoi Leong Xavier, Li, Min
Publicado 2022

Targeting Aggrephagy for the Treatment of Alzheimer’s Disease

por Malampati, Sandeep, Song, Ju-Xian, Chun-Kit Tong, Benjamin, Nalluri, Anusha, Yang, Chuan-Bin, Wang, Ziying, Gopalkrishnashetty Sreenivasmurthy, Sravan, Zhu, Zhou, Liu, Jia, Su, Chengfu, Krishnamoorthi, Senthilkumar, Iyaswamy, Ashok, Cheung, King-Ho, Lu, Jia-Hong, Li, Min
Publicado 2020

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

por Iyaswamy, Ashok, Thakur, Abhimanyu, Guan, Xin-Jie, Krishnamoorthi, Senthilkumar, Fung, Tsz Yan, Lu, Kejia, Gaurav, Isha, Yang, Zhijun, Su, Cheng-Fu, Lau, Kwok-Fai, Zhang, Kui, Ng, Roy Chun-Laam, Lian, Qizhou, Cheung, King-Ho, Ye, Keqiang, Chen, Huanhuan Joyce, Li, Min
Publicado 2023

Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

por Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju-Xian, Tong, Benjamin Chun-kit, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Cheung, King-Ho, Lu, Jia-Hong, Tan, Jie-Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min
Publicado 2022

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy

por Sreenivasmurthy, Sravan Gopalkrishnashetty, Iyaswamy, Ashok, Krishnamoorthi, Senthilkumar, Reddi, Rambabu N., Kammala, Ananth Kumar, Vasudevan, Karthick, Senapati, Sanjib, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Guan, Xin-Jie, Chua, Ka-Kit, Cheung, King-Ho, Chen, Hubiao, Zhang, Hong-Jie, Zhang, Yuan, Song, Ju-Xian, Kumar Durairajan, Siva Sundara, Li, Min
Publicado 2022