Cooperative Genomic Lesions in HRAS-Mutant Cancers Predict Resistance to Farnesyltransferase Inhibitors

por Nigam, Aradhya, Krishnamoorthy, Gnana, Chatila, Walid, Berman, Katherine, Saqcena, Mahesh, Walch, Henry, Ho, Alan, Schultz, Nikolaus, Fagin, James, Untch, Brian
Publicado 2023

Telomerase reactivation induces progression of mouse Braf(V600E)-driven thyroid cancers without telomere lengthening

por Landa, Iñigo, Thornton, Caitlin EM, Xu, Bin, Haase, Jacob, Krishnamoorthy, Gnana P., Hao, Jingzhu, Knauf, Jeffrey A, Herbert, Zachary T, Blasco, María A, Ghossein, Ronald, Fagin, James A
Publicado 2023

Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors

por Garcia-Rendueles, Maria E. R., Krishnamoorthy, Gnana, Saqcena, Mahesh, Acuña-Ruiz, Adrian, Revilla, Giovanna, de Stanchina, Elisa, Knauf, Jeffrey A., Lester, Rona, Xu, Bin, Ghossein, Ronald A., Fagin, James A.
Publicado 2022

Co-inhibition of SMAD and MAPK signaling enhances (124)I uptake in BRAF-mutant thyroid cancers

por Luckett, Kathleen A, Cracchiolo, Jennifer R, Krishnamoorthy, Gnana P, Leandro-Garcia, Luis Javier, Nagarajah, James, Saqcena, Mahesh, Lester, Rona, Im, Soo Y, Zhao, Zhen, Lowe, Scott W, de Stanchina, Elisa, Sherman, Eric J, Ho, Alan L, Leach, Steven D, Knauf, Jeffrey A, Fagin, James A
Publicado 2021