Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis

por Krishnamurthy, Pranathi Meda, Shukla, Shirish, Ray, Paramita, Mehra, Rohit, Nyati, Mukesh K, Lawrence, Theodore S, Ray, Dipankar
Publicado 2017

Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA

por Pendergraff, Hannah M., Krishnamurthy, Pranathi Meda, Debacker, Alexandre J., Moazami, Michael P., Sharma, Vivek K., Niitsoo, Liisa, Yu, Yong, Tan, Yen Nee, Haitchi, Hans Michael, Watts, Jonathan K.
Publicado 2017

G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects

por Wang, Feng, Calvo-Roitberg, Ezequiel, Rembetsy-Brown, Julia M, Fang, Minggang, Sousa, Jacquelyn, Kartje, Zachary J, Krishnamurthy, Pranathi Meda, Lee, Jonathan, Green, Michael R, Pai, Athma A, Watts, Jonathan K
Publicado 2022

Tristetraprolin Mediates Radiation-Induced TNF-α Production in Lung Macrophages

por Ray, Dipankar, Shukla, Shirish, Allam, Uday Sankar, Helman, Abigail, Ramanand, Susmita Gurjar, Tran, Linda, Bassetti, Michael, Krishnamurthy, Pranathi Meda, Rumschlag, Matthew, Paulsen, Michelle, Sun, Lei, Shanley, Thomas P., Ljungman, Mats, Nyati, Mukesh K., Zhang, Ming, Lawrence, Theodore S.
Publicado 2013

Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts

por Shin, Minwook, Chan, Io Long, Cao, Yuming, Gruntman, Alisha M, Lee, Jonathan, Sousa, Jacquelyn, Rodríguez, Tomás C, Echeverria, Dimas, Devi, Gitali, Debacker, Alexandre J, Moazami, Michael P, Krishnamurthy, Pranathi Meda, Rembetsy-Brown, Julia M, Kelly, Karen, Yukselen, Onur, Donnard, Elisa, Parsons, Teagan J, Khvorova, Anastasia, Sontheimer, Erik J, Maehr, René, Garber, Manuel, Watts, Jonathan K
Publicado 2022

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

por Hariharan, Vignesh N., Shin, Minwook, Chang, Ching-Wen, O’Reilly, Daniel, Biscans, Annabelle, Yamada, Ken, Guo, Zhiru, Somasundaran, Mohan, Tang, Qi, Monopoli, Kathryn, Krishnamurthy, Pranathi Meda, Devi, Gitali, McHugh, Nicholas, Cooper, David A., Echeverria, Dimas, Cruz, John, Chan, Io Long, Liu, Ping, Lim, Sun-Young, McConnell, Jill, Singh, Satya Prakash, Hildebrand, Samuel, Sousa, Jacquelyn, Davis, Sarah M., Kennedy, Zachary, Ferguson, Chantal, Godinho, Bruno M. D. C., Thillier, Yann, Caiazzi, Jillian, Ly, Socheata, Muhuri, Manish, Kelly, Karen, Humphries, Fiachra, Cousineau, Alyssa, Parsi, Krishna Mohan, Li, Qi, Wang, Yang, Maehr, René, Gao, Guangping, Korkin, Dmitry, McDougall, William M., Finberg, Robert W., Fitzgerald, Katherine A., Wang, Jennifer P., Watts, Jonathan K., Khvorova, Anastasia
Publicado 2023