Dataset of the binding kinetic rate constants of anti-PCSK9 antibodies obtained using the Biacore T100, ProteOn XPR36, Octet RED384, and IBIS MX96 biosensor platforms

por Yang, Danlin, Singh, Ajit, Wu, Helen, Kroe-Barrett, Rachel
Publicado 2016

Determination of High-affinity Antibody-antigen Binding Kinetics Using Four Biosensor Platforms

por Yang, Danlin, Singh, Ajit, Wu, Helen, Kroe-Barrett, Rachel
Publicado 2017

IgG Charge: Practical and Biological Implications

por Yang, Danlin, Kroe-Barrett, Rachel, Singh, Sanjaya, Laue, Thomas
Publicado 2019

Efficient Qualitative and Quantitative Determination of Antigen-induced Immune Responses

por Yang, Danlin, Frego, Lee, Lasaro, Marcio, Truncali, Kristopher, Kroe-Barrett, Rachel, Singh, Sanjaya
Publicado 2016

IgG cooperativity – Is there allostery? Implications for antibody functions and therapeutic antibody development

por Yang, Danlin, Kroe-Barrett, Rachel, Singh, Sanjaya, Roberts, Christopher J., Laue, Thomas M.
Publicado 2017

X‐ray crystal structure localizes the mechanism of inhibition of an IL‐36R antagonist monoclonal antibody to interaction with Ig1 and Ig2 extra cellular domains

por Larson, Eric T., Brennan, Debra L., Hickey, Eugene R., Ganesan, Raj, Kroe‐Barrett, Rachel, Farrow, Neil A.
Publicado 2020

Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy

por Zippel, Nina, Kenny, Cynthia Hess, Wu, Helen, Garneau, Michel, Kroe-Barrett, Rachel, Gupta, Priyanka, Low, Sarah, Bakker, Remko A., Thomas, Leo
Publicado 2022

Distinct immune stimulatory effects of anti-human VISTA antibodies are determined by Fc-receptor interaction

por Mostböck, Sven, Wu, Helen Haixia, Fenn, Timothy, Riegler, Bettina, Strahlhofer, Susanne, Huang, Yining, Hansen, Gale, Kroe-Barrett, Rachel, Tirapu, Iñigo, Vogt, Anne B.
Publicado 2022

Non-neutralizing antibodies increase endogenous circulating Ang1 levels

por Zheng, Chao, Toth, Joshuaine, Bigwarfe, Tammy, MacDougall, Margit, Jerath, Kavita, Bovat, Kristin, Smith, James, Sun, Peng, Hayes, David, Fryer, Ryan, Singh, Sanjaya, Kroe-Barrett, Rachel
Publicado 2018

Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn

por Yang, Danlin, Giragossian, Craig, Castellano, Steven, Lasaro, Marcio, Xiao, Haiguang, Saraf, Himanshu, Hess Kenny, Cynthia, Rybina, Irina, Huang, Zhong-Fu, Ahlberg, Jennifer, Bigwarfe, Tammy, Myzithras, Maria, Waltz, Erica, Roberts, Simon, Kroe-Barrett, Rachel, Singh, Sanjaya
Publicado 2017

Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody

por Singh, Sanjaya, Kroe-Barrett, Rachel R, Canada, Keith A, Zhu, Xiang, Sepulveda, Eliud, Wu, Helen, He, Yaqin, Raymond, Ernest L, Ahlberg, Jennifer, Frego, Lee E, Amodeo, Laura M, Catron, Katrina M, Presky, David H, Hanke, Jeffrey H
Publicado 2015

Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA exp...

por Ahlberg, Jennifer, Giragossian, Craig, Li, Hua, Myzithras, Maria, Raymond, Ernie, Caviness, Gary, Grimaldi, Christine, Brown, Su-Ellen, Perez, Rocio, Yang, Danlin, Kroe-Barrett, Rachel, Joseph, David, Pamulapati, Chandrasena, Coble, Kelly, Ruus, Peter, Woska, Joseph R., Ganesan, Rajkumar, Hansel, Steven, Mbow, M. Lamine
Publicado 2019

VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis

por Low, Sarah, Wu, Haixia, Jerath, Kavita, Tibolla, Annette, Fogal, Birgit, Conrad, Rebecca, MacDougall, Margit, Kerr, Steven, Berger, Valentina, Dave, Rajvee, Villalona, Jorge, Pantages, Lynn, Ahlberg, Jennifer, Li, Hua, Van Hoorick, Diane, Ververken, Cedric, Broadwater, John, Waterman, Alisa, Singh, Sanjaya, Kroe-Barrett, Rachel
Publicado 2020

A Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway

por Wurm, Melanie, Schaaf, Otmar, Reutner, Katharina, Ganesan, Rajkumar, Mostböck, Sven, Pelster, Christina, Böttcher, Jark, de Andrade Pereira, Bruna, Taubert, Christina, Alt, Isabella, Serna, Garazi, Auguste, Aurelie, Stadermann, Kai B., Delic, Denis, Han, Fei, Capdevila, Jaume, Nuciforo, Paolo G., Kroe-Barrett, Rachel, Adam, Paul J., Vogt, Anne B., Hofmann, Irmgard
Publicado 2021

Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies

por Ganesan, Rajkumar, Raymond, Ernest L., Mennerich, Detlev, Woska, Joseph R., Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D., Canada, Keith A., Kroe-Barrett, Rachel, Fine, Jay S., Singh, Sanjaya, Mbow, M. Lamine
Publicado 2017