Function-Altering SNPs in the Human Multidrug Transporter Gene ABCB1 Identified Using a Saccharomyces-Based Assay

por Jeong, Hotcherl, Herskowitz, Ira, Kroetz, Deanna L, Rine, Jasper
Publicado 2007

Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine

por Hoppe, Reiner, Brauch, Hiltrud, Kroetz, Deanna L, Esteller, Manel
Publicado 2011

Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy

por Stage, Tore B., Hu, Shuiying, Sparreboom, Alex, Kroetz, Deanna L.
Publicado 2020

Multidrug resistance-associated protein 4 is a determinant of arsenite resistance

por Yuan, Bo, Yoshino, Yuta, Fukushima, Hisayo, Markova, Svetlana, Takagi, Norio, Toyoda, Hiroo, Kroetz, Deanna L.
Publicado 2016

Steady State Bioequivalence of Generic and Innovator Formulations of Stavudine, Lamivudine, and Nevirapine in HIV-Infected Ugandan Adults

por Byakika-Tusiime, Jayne, Chinn, Leslie W., Oyugi, Jessica H., Obua, Celestino, Bangsberg, David R., Kroetz, Deanna L.
Publicado 2008

Discovery of Regulatory Elements in Human ATP-Binding Cassette Transporters through Expression Quantitative Trait Mapping

por Matsson, Pär, Yee, Sook Wah, Markova, Svetlana, Morrissey, Kari, Jenkins, Gerard, Xuan, Jiekun, Jorgenson, Eric, Kroetz, Deanna L., Giacomini, Kathleen M.
Publicado 2011

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers

por Yee, Sook Wah, Giacomini, Marilyn M., Shen, Hong, Humphreys, W. Griffith, Horng, Howard, Brian, William, Lai, Yurong, Kroetz, Deanna L., Giacomini, Kathleen M.
Publicado 2019

FUNCTIONAL CHARACTERIZATION OF ABCC2 PROMOTER POLYMORPHISMS AND ALLELE SPECIFIC EXPRESSION

por Nguyen, Tan D., Markova, Svetlana, Liu, Wanqing, Gow, Jason M., Baldwin, R. Michael, Habashian, Mahnoush, Relling, Mary V., Ratain, Mark J., Kroetz, Deanna L.
Publicado 2012

Efficient estimation of grouped survival models

por Li, Zhiguo, Lin, Jiaxing, Sibley, Alexander B., Truong, Tracy, Chua, Katherina C., Jiang, Yu, McCarthy, Janice, Kroetz, Deanna L., Allen, Andrew, Owzar, Kouros
Publicado 2019

A survey of integral α-helical membrane proteins

por Kelly, Libusha, Pieper, Ursula, Eswar, Narayanan, Hays, Franklin A., Li, Min, Roe-Zurz, Zygy, Kroetz, Deanna L., Giacomini, Kathleen M., Stroud, Robert M., Sali, Andrej
Publicado 2009

GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel‐Based Chemotherapy in Ovarian Cancer

por Ferracini, Amanda Canato, Lopes-Aguiar, Leisa, Lourenço, Gustavo Jacob, Yoshida, Adriana, Lima, Carmen Silva Passos, Sarian, Luis Otávio, Derchain, Sophie, Kroetz, Deanna L., Mazzola, Priscila Gava
Publicado 2020

New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium

por Giacomini, Kathleen M., Yee, Sook W., Koleske, Megan L., Zou, Ling, Matsson, Pär, Chen, Eugene C., Kroetz, Deanna L., Miller, Miles A., Gozalpour, Elnaz, Chu, Xiaoyan
Publicado 2022

Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel

por Xiong, Chenling, Chua, Katherina C., Stage, Tore B., Priotti, Josefina, Kim, Jeffrey, Altman‐Merino, Anne, Chan, Daniel, Saraf, Krishna, Canato Ferracini, Amanda, Fattahi, Faranak, Kroetz, Deanna L.
Publicado 2020

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle

por Bartelink, Imke H., Jones, Ella F., Shahidi‐Latham, Sheerin K., Lee, Pei Rong Evelyn, Zheng, Yanan, Vicini, Paolo, van ‘t Veer, Laura, Wolf, Denise, Iagaru, Andrei, Kroetz, Deanna L., Prideaux, Brendan, Cilliers, Cornelius, Thurber, Greg M., Wimana, Zena, Gebhart, Geraldine
Publicado 2018

Polygenic Inheritance of Paclitaxel-Induced Sensory Peripheral Neuropathy Driven by Axon Outgrowth Gene Sets in CALGB 40101 (Alliance)

por Chhibber, Aparna, Mefford, Joel, Stahl, Eli A., Pendergrass, Sarah A., Baldwin, R. Michael, Owzar, Kouros, Li, Megan, Winer, Eric P., Hudis, Clifford A., Zembutsu, Hitoshi, Kubo, Michiaki, Nakamura, Yusuke, McLeod, Howard L., Ratain, Mark J., Shulman, Lawrence N., Ritchie, Marylyn D., Plenge, Robert M., Witte, John S., Kroetz, Deanna L.
Publicado 2014

Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation

por Hesselson, Stephanie E., Matsson, Pär, Shima, James E., Fukushima, Hisayo, Yee, Sook Wah, Kobayashi, Yuya, Gow, Jason M., Ha, Connie, Ma, Benjamin, Poon, Annie, Johns, Susan J., Stryke, Doug, Castro, Richard A., Tahara, Harunobu, Choi, Ji Ha, Chen, Ligong, Picard, Nicolas, Sjödin, Elin, Roelofs, Maarke J. E., Ferrin, Thomas E., Myers, Richard, Kroetz, Deanna L., Kwok, Pui-Yan, Giacomini, Kathleen M.
Publicado 2009

Host variation in type I interferon signaling genes (MX1), C–C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers p...

por Siegel, David A., Thanh, Cassandra, Wan, Eunice, Hoh, Rebecca, Hobbs, Kristen, Pan, Tony, Gibson, Erica A., Kroetz, Deanna L., Martin, Jeffrey, Hecht, Frederick, Pilcher, Christopher, Martin, Maureen, Carrington, Mary, Pillai, Satish, Busch, Michael P., Stone, Mars, Levy, Claire N., Huang, Meei-Li, Roychoudhury, Pavitra, Hladik, Florian, Jerome, Keith R., Kiem, Hans-Peter, Henrich, Timothy J., Deeks, Steven G., Lee, Sulggi A.
Publicado 2023