Combined BCL-2 and PI3K/AKT Pathway Inhibition in KMT2A-Rearranged Acute B-Lymphoblastic Leukemia Cells

por Holz, Clemens, Lange, Sandra, Sekora, Anett, Knuebel, Gudrun, Krohn, Saskia, Murua Escobar, Hugo, Junghanss, Christian, Richter, Anna
Publicado 2023

Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalen...

por Grunwald, Luise, Grosse-Thie, Christina, Sender, Sina, Knuebel, Gudrun, Krohn, Saskia, Roolf, Catrin, Junghanss, Christian, Henze, Larissa, Murua Escobar, Hugo
Publicado 2020

Generation and Characterization of a CRISPR/Cas9-Mediated SNAP29 Knockout in Human Fibroblasts

por Martens, Marie Christine, Edelkamp, Janin, Seebode, Christina, Schäfer, Mirijam, Stählke, Susanne, Krohn, Saskia, Jung, Ole, Murua Escobar, Hugo, Emmert, Steffen, Boeckmann, Lars
Publicado 2021

Effective tumor cell abrogation via Venetoclax-mediated BCL-2 inhibition in KMT2A-rearranged acute B-lymphoblastic leukemia

por Richter, Anna, Lange, Sandra, Holz, Clemens, Brock, Luisa, Freitag, Thomas, Sekora, Anett, Knuebel, Gudrun, Krohn, Saskia, Schwarz, Rico, Hinz, Burkhard, Murua Escobar, Hugo, Junghanss, Christian
Publicado 2022

The Molecular Subtype of Adult Acute Lymphoblastic Leukemia Samples Determines the Engraftment Site and Proliferation Kinetics in Patient-Derived Xenograft Models

por Richter, Anna, Roolf, Catrin, Sekora, Anett, Knuebel, Gudrun, Krohn, Saskia, Lange, Sandra, Krebs, Vivien, Schneider, Bjoern, Lakner, Johannes, Wittke, Christoph, Kiefel, Christoph, Jeremias, Irmela, Murua Escobar, Hugo, Vollmar, Brigitte, Junghanss, Christian
Publicado 2022