Spacial Score—A Comprehensive Topological Indicator for Small-Molecule Complexity

por Krzyzanowski, Adrian, Pahl, Axel, Grigalunas, Michael, Waldmann, Herbert
Publicado 2023

Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5–MEP50 Complex

por Krzyzanowski, Adrian, Gasper, Raphael, Adihou, Hélène, Hart, Peter 't, Waldmann, Herbert
Publicado 2021

Development of Macrocyclic PRMT5–Adaptor Protein Interaction Inhibitors

por Krzyzanowski, Adrian, Esser, Lea Marie, Willaume, Anthony, Prudent, Renaud, Peter, Christoph, ‘t Hart, Peter, Waldmann, Herbert
Publicado 2022

Unprecedented Combination of Polyketide Natural Product Fragments Identifies the New Hedgehog Signaling Pathway Inhibitor Grismonone

por Grigalunas, Michael, Patil, Sohan, Krzyzanowski, Adrian, Pahl, Axel, Flegel, Jana, Schölermann, Beate, Xie, Jianing, Sievers, Sonja, Ziegler, Slava, Waldmann, Herbert
Publicado 2022

Structure Based Design of Bicyclic Peptide Inhibitors of RbAp48

por Hart, Peter 't, Hommen, Pascal, Noisier, Anaïs, Krzyzanowski, Adrian, Schüler, Darijan, Porfetye, Arthur T., Akbarzadeh, Mohammad, Vetter, Ingrid R., Adihou, Hélène, Waldmann, Herbert
Publicado 2020

The Pseudo‐Natural Product Rhonin Targets RHOGDI

por Akbarzadeh, Mohammad, Flegel, Jana, Patil, Sumersing, Shang, Erchang, Narayan, Rishikesh, Buchholzer, Marcel, Kazemein Jasemi, Neda S., Grigalunas, Michael, Krzyzanowski, Adrian, Abegg, Daniel, Shuster, Anton, Potowski, Marco, Karatas, Hacer, Karageorgis, George, Mosaddeghzadeh, Niloufar, Zischinsky, Mia‐Lisa, Merten, Christian, Golz, Christopher, Brieger, Lucas, Strohmann, Carsten, Antonchick, Andrey P., Janning, Petra, Adibekian, Alexander, Goody, Roger S., Ahmadian, Mohammad Reza, Ziegler, Slava, Waldmann, Herbert
Publicado 2022

The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation

por Flegel, Jana, Shaaban, Saad, Jia, Zhi Jun, Schulte, Britta, Lian, Yilong, Krzyzanowski, Adrian, Metz, Malte, Schneidewind, Tabea, Wesseler, Fabian, Flegel, Anke, Reich, Alisa, Brause, Alexandra, Xue, Gang, Zhang, Minghao, Dötsch, Lara, Stender, Isabelle D., Hoffmann, Jan-Erik, Scheel, Rebecca, Janning, Petra, Rastinejad, Fraydoon, Schade, Dennis, Strohmann, Carsten, Antonchick, Andrey P., Sievers, Sonja, Moura-Alves, Pedro, Ziegler, Slava, Waldmann, Herbert
Publicado 2022