Structure-Function Relationship of TRPM2: Recent Advances, Contradictions, and Open Questions

por Kühn, Frank J.P.
Publicado 2020

Three pillars of organization and leadership in disruptive times: navigating your company successfully through the 21st century business world

por Wollmann, Peter, Kühn, Frank, Kempf, Michael
Publicado 2019

Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone

por Kühn, Frank, Kühn, Cornelia, Lückhoff, Andreas
Publicado 2017

Movement of Voltage Sensor S4 in Domain 4 Is Tightly Coupled to Sodium Channel Fast Inactivation and Gating Charge Immobilization

por Kühn, Frank J.P., Greeff, Nikolaus G.
Publicado 1999

Functional Characterisation of a TRPM2 orthologue from the sea anemone Nematostella vectensis in human cells

por Kühn, Frank J. P., Kühn, Cornelia, Lückhoff, Andreas
Publicado 2015

Species-Specific Regulation of TRPM2 by PI(4,5)P(2) via the Membrane Interfacial Cavity

por Barth, Daniel, Lückhoff, Andreas, Kühn, Frank J. P.
Publicado 2021

Functional importance of NUDT9H domain and N-terminal ADPR-binding pocket in two species variants of vertebrate TRPM2 channels

por Kühn, Frank J. P., Ehrlich, Wiebke, Barth, Daniel, Kühn, Cornelia, Lückhoff, Andreas
Publicado 2019

ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain

por Kühn, Frank J. P., Kühn, Cornelia, Winking, Mathis, Hoffmann, Daniel C., Lückhoff, Andreas
Publicado 2016

Modulation of activation and inactivation by Ca(2+) and 2-APB in the pore of an archetypal TRPM channel from Nematostella vectensis

por Kühn, Frank J. P., Mathis, Winking, Cornelia, Kühn, Hoffmann, Daniel C., Lückhoff, Andreas
Publicado 2017

Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR

por Kühn, Frank J. P., Watt, Joanna M., Potter, Barry V. L., Lückhoff, Andreas
Publicado 2019

Importance of a Conserved Sequence Motif in Transmembrane Segment S3 for the Gating of Human TRPM8 and TRPM2

por Winking, Mathis, Hoffmann, Daniel C., Kühn, Cornelia, Hilgers, Ralf-Dieter, Lückhoff, Andreas, Kühn, Frank J. P.
Publicado 2012

H(2)O(2)-induced Ca(2+) influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the β-cells: involvement of TRPM2 channels

por Bari, Muhammad R, Akbar, Sanian, Eweida, Mohamed, Kühn, Frank JP, Gustafsson, Amanda Jabin, Lückhoff, Andreas, Islam, Md Shahidul
Publicado 2009

A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial‐onset seizures in daily clinical practic...

por Runge, Uwe, Arnold, Stephan, Brandt, Christian, Reinhardt, Fritjof, Kühn, Frank, Isensee, Kathleen, Ramirez, Francisco, Dedeken, Peter, Lauterbach, Thomas, Noack‐Rink, Matthias, Mayer, Thomas
Publicado 2015