Towards reperfusion-centric preclinical stroke research: outside the box of “reperfusion injury”

por Kuan, Chia Yi, Sun, Yu Yo
Publicado 2015

(Phospho)creatine: the reserve and merry-go-round of brain energetics

por Chen, Hong-Ru, DeGrauw, Ton, Kuan, Chia-Yi
Publicado 2022

Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease

por Jo, Hakryul, Patterson, Victoria, Stoessel, Sean, Kuan, Chia-Yi, Hoh, Josephine
Publicado 2014

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway

por Nagao, Motoshi, Campbell, Kenneth, Burns, Kevin, Kuan, Chia-Yi, Trumpp, Andreas, Nakafuku, Masato
Publicado 2008

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway

por Nagao, Motoshi, Campbell, Kenneth, Burns, Kevin, Kuan, Chia-Yi, Trumpp, Andreas, Nakafuku, Masato
Publicado 2009

Impaired post-stroke collateral circulation in sickle cell anemia mice

por Bian, Emily J., Chen, Ching-Wen, Cheng, Chih-Mei, Kuan, Chia-Yi, Sun, Yu-Yo
Publicado 2023

Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia

por Sun, Yu-Yo, Yao, Hui-Wen, Chen, Hong-Ru, Chen, Ching-Wen, Kinkaid, Melissa M., Kuan, Chia-Yi
Publicado 2022

Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy

por Li, Yikun, Dammer, Eric B., Zhang-Brotzge, Xiaohui, Chen, Scott, Duong, Duc M., Seyfried, Nicholas T., Kuan, Chia-Yi, Sun, Yu-Yo
Publicado 2017

Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice

por Weng, Daniel Y., Zhang, Yujin, Hayashi, Yasuhito, Kuan, Chia-Yi, Liu, Chia-Yang, Babcock, George, Weng, Wei-Lan, Schwemberger, Sandy, Kao, Winston W.-Y.
Publicado 2008

Monocytes promote acute neuroinflammation and become pathological microglia in neonatal hypoxic-ischemic brain injury

por Chen, Hong-Ru, Chen, Ching-Wen, Kuo, Yi-Min, Chen, Brandon, Kuan, Irena S., Huang, Henry, Lee, Jolly, Anthony, Neil, Kuan, Chia-Yi, Sun, Yu-Yo
Publicado 2022

Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke

por Sun, Yu-Yo, Morozov, Yury M., Yang, Dianer, Li, Yikun, Dunn, R. Scott, Rakic, Pasko, Chan, Pak H., Abe, Koji, Lindquist, Diana M., Kuan, Chia-Yi
Publicado 2014

Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain

por Hernandes, Marina S., Lassègue, Bernard, Hilenski, Lula L., Adams, Jonathan, Gao, Ning, Kuan, Chia-Yi, Sun, Yu-Yo, Cheng, Lihong, Kikuchi, Daniel S., Yepes, Manuel, Griendling, Kathy K.
Publicado 2018

Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke

por Chen, Hong-Ru, Sun, Yu-Yo, Chen, Ching-Wen, Kuo, Yi-Min, Kuan, Irena S., Tiger Li, Zheng-Rong, Short-Miller, Jonah C., Smucker, Marchelle R., Kuan, Chia-Yi
Publicado 2020

Neural-Specific Deletion of Htra2 Causes Cerebellar Neurodegeneration and Defective Processing of Mitochondrial OPA1

por Patterson, Victoria L., Zullo, Alfred J., Koenig, Claire, Stoessel, Sean, Jo, Hakryul, Liu, Xinran, Han, Jinah, Choi, Murim, DeWan, Andrew T., Thomas, Jean-Leon, Kuan, Chia-Yi, Hoh, Josephine
Publicado 2014

Cell Type-Specific Dependency on the PI3K/Akt Signaling Pathway for the Endogenous Epo and VEGF Induction by Baicalein in Neurons versus Astrocytes

por Sun, Yu-Yo, Lin, Shang-Hsuan, Lin, Hung-Cheng, Hung, Chia-Chi, Wang, Chen-Yu, Lin, Yen-Chu, Hung, Kuo-Sheng, Lien, Cheng-Chang, Kuan, Chia-Yi, Lee, Yi-Hsuan
Publicado 2013

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction

por Eidson, Lori N., Gao, Qingzeng, Qu, Hongyan, Kikuchi, Daniel S., Campos, Ana Carolina P., Faidley, Elizabeth A., Sun, Yu-Yo, Kuan, Chia-Yi, Pagano, Rosana L., Lassègue, Bernard, Tansey, Malú G., Griendling, Kathy K., Hernandes, Marina S.
Publicado 2021

Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke

por Su, Enming Joseph, Cao, Chunzhang, Fredriksson, Linda, Nilsson, Ingrid, Stefanitsch, Christina, Stevenson, Tamara K., Zhao, Juanjuan, Ragsdale, Margret, Sun, Yu-Yo, Yepes, Manuel, Kuan, Chia-Yi, Eriksson, Ulf, Strickland, Dudley K., Lawrence, Daniel A., Zhang, Li
Publicado 2017

Creatine transporter deficiency impairs stress adaptation and brain energetics homeostasis

por Chen, Hong-Ru, Zhang-Brotzge, Xiaohui, Morozov, Yury M., Li, Yuancheng, Wang, Siming, Zhang, Helen Heju, Kuan, Irena S., Fugate, Elizabeth M., Mao, Hui, Sun, Yu-Yo, Rakic, Pasko, Lindquist, Diana M., DeGrauw, Ton, Kuan, Chia-Yi
Publicado 2021

Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium

por Kim, Young-Woong, Zara, Greta, Kang, HyunJun, Branciamore, Sergio, O’Meally, Denis, Feng, Yuxin, Kuan, Chia-Yi, Luo, Yingjun, Nelson, Michael S., Brummer, Alex B., Rockne, Russell, Chen, Zhen Bouman, Zheng, Yi, Cardoso, Angelo A., Carlesso, Nadia
Publicado 2022

Neurovascular protection by adropin in experimental ischemic stroke through an endothelial nitric oxide synthase-dependent mechanism

por Yang, Changjun, Lavayen, Bianca P., Liu, Lei, Sanz, Brian D., DeMars, Kelly M., Larochelle, Jonathan, Pompilus, Marjory, Febo, Marcelo, Sun, Yu-Yo, Kuo, Yi-Min, Mohamadzadeh, Mansour, Farr, Susan A., Kuan, Chia-Yi, Butler, Andrew A., Candelario-Jalil, Eduardo
Publicado 2021