Hypoxia‐inducible factor‐targeting prodrug TOP3 combined with gemcitabine or TS‐1 improves pancreatic cancer survival in an orthotopic model

por Hoang, Ngoc Thi Hong, Kadonosono, Tetsuya, Kuchimaru, Takahiro, Kizaka‐Kondoh, Shinae
Publicado 2016

A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system

por Kuchimaru, Takahiro, Suka, Tomoya, Hirota, Keisuke, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae
Publicado 2016

In Vivo Imaging of HIF-Active Tumors by an Oxygen-Dependent Degradation Protein Probe with an Interchangeable Labeling System

por Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Ushiki, Takashi, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae
Publicado 2010

Microfluidic High-Migratory Cell Collector Suppressing Artifacts Caused by Microstructures

por Ishida, Tadashi, Shimamoto, Takuya, Kaminaga, Maho, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae, Omata, Toru
Publicado 2019

Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor

por Ngamlertwong, Nuttawadee, Tsuchiya, Hiroyoshi, Mochimaru, Yuta, Azuma, Morio, Kuchimaru, Takahiro, Koshimizu, Taka-aki
Publicado 2021

Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia

por Kuchimaru, Takahiro, Hoshino, Takuya, Aikawa, Tomoya, Yasuda, Hisataka, Kobayashi, Tatsuya, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae
Publicado 2014

Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress

por Ishida, Tadashi, Shimamoto, Takuya, Ozaki, Nobuya, Takaki, Satoshi, Kuchimaru, Takahiro, Kizaka-Kondoh, Sinae, Omata, Toru
Publicado 2016

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

por Kuchimaru, Takahiro, Iwano, Satoshi, Kiyama, Masahiro, Mitsumata, Shun, Kadonosono, Tetsuya, Niwa, Haruki, Maki, Shojiro, Kizaka-Kondoh, Shinae
Publicado 2016

A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries

por Kuchimaru, Takahiro, Kataoka, Naoya, Nakagawa, Kenji, Isozaki, Tatsuhiro, Miyabara, Hitomi, Minegishi, Misa, Kadonosono, Tetsuya, Kizaka-Kondoh, Shinae
Publicado 2018

A Fluorescent Protein Scaffold for Presenting Structurally Constrained Peptides Provides an Effective Screening System to Identify High Affinity Target-Binding Peptides

por Kadonosono, Tetsuya, Yabe, Etsuri, Furuta, Tadaomi, Yamano, Akihiro, Tsubaki, Takuya, Sekine, Takuya, Kuchimaru, Takahiro, Sakurai, Minoru, Kizaka-Kondoh, Shinae
Publicado 2014

The effect of triamcinolone acetonide on laser-induced choroidal neovascularization in mice using a hypoxia visualization bio-imaging probe

por Takata, Shinsuke, Masuda, Tomomi, Nakamura, Shinsuke, Kuchimaru, Takahiro, Tsuruma, Kazuhiro, Shimazawa, Masamitsu, Nagasawa, Hideko, kizaka-Kondoh, Shinae, Hara, Hideaki
Publicado 2015

In Vivo Imaging of Brain Ischemia Using an Oxygen-Dependent Degradative Fusion Protein Probe

por Fujita, Youshi, Kuchimaru, Takahiro, Kadonosono, Tetsuya, Tanaka, Shotaro, Hase, Yoshiki, Tomimoto, Hidekazu, Hiraoka, Masahiro, Kizaka-Kondoh, Shinae, Ihara, Masafumi, Takahashi, Ryosuke
Publicado 2012

Novel lymphoid enhancer‐binding factor 1‐cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs

por Pongsuchart, Mongkol, Kuchimaru, Takahiro, Yonezawa, Sakiko, Tran, Diem Thi Phuong, Kha, Nguyen The, Hoang, Ngoc Thi Hong, Kadonosono, Tetsuya, Kizaka‐Kondoh, Shinae
Publicado 2018

Novel adherent CD11b(+) Gr-1(+) tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment

por Tsubaki, Takuya, Kadonosono, Tetsuya, Sakurai, Shimon, Shiozawa, Tadashi, Goto, Toshiki, Sakai, Shiori, Kuchimaru, Takahiro, Sakamoto, Takeharu, Watanabe, Hitomi, Kondoh, Gen, Kizaka-Kondoh, Shinae
Publicado 2018

Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use

por Kadonosono, Tetsuya, Yimchuen, Wanaporn, Ota, Yumi, See, Kyra, Furuta, Tadaomi, Shiozawa, Tadashi, Kitazawa, Maika, Goto, Yu, Patil, Akash, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae
Publicado 2020

Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold

por Yimchuen, Wanaporn, Kadonosono, Tetsuya, Ota, Yumi, Sato, Shinichi, Kitazawa, Maika, Shiozawa, Tadashi, Kuchimaru, Takahiro, Taki, Masumi, Ito, Yuji, Nakamura, Hiroyuki, Kizaka-Kondoh, Shinae
Publicado 2020

Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display

por See, Kyra, Kadonosono, Tetsuya, Miyamoto, Kotaro, Tsubaki, Takuya, Ota, Yumi, Katsumi, Marina, Ryo, Sumoe, Aida, Kazuki, Minegishi, Misa, Isozaki, Tatsuhiro, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae
Publicado 2021

AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures

por Kadonosono, Tetsuya, Miyamoto, Kotaro, Sakai, Shiori, Matsuo, Yoshiyuki, Kitajima, Shojiro, Wang, Qiannan, Endo, Minori, Niibori, Mizuho, Kuchimaru, Takahiro, Soga, Tomoyoshi, Hirota, Kiichi, Kizaka-Kondoh, Shinae
Publicado 2022

In vivo optical imaging of tumor stromal cells with hypoxia‐inducible factor activity

por Miyabara, Hitomi, Hirano, Ryuichiro, Watanabe, Shigeaki, Soriano, John Clyde Co, Watanabe, Hitomi, Kuchimaru, Takahiro, Kitada, Nobuo, Kadonosono, Tetsuya, Maki, Shojiro A., Kondoh, Gen, Kizaka‐Kondoh, Shinae
Publicado 2023

Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells

por Iizuka-Ohashi, Mahiro, Watanabe, Motoki, Sukeno, Mamiko, Morita, Mie, Hoang, Ngoc Thi Hong, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae, Sowa, Yoshihiro, Sakaguchi, Koichi, Taguchi, Tetsuya, Sakai, Toshiyuki
Publicado 2018