Immunomodulation by Inflammation during Liver and Gastrointestinal Tumorigenesis and Aging

por Nagai, Nao, Kudo, Yotaro, Aki, Daisuke, Nakagawa, Hayato, Taniguchi, Koji
Publicado 2021

An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis

por Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Kudo, Yotaro, Diaz-Meco, Maria T., Moscat, Jorge
Publicado 2020

Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis

por Nakatsuka, Takuma, Tateishi, Keisuke, Kato, Hiroyuki, Fujiwara, Hiroaki, Yamamoto, Keisuke, Kudo, Yotaro, Nakagawa, Hayato, Tanaka, Yasuo, Ijichi, Hideaki, Ikenoue, Tsuneo, Ishizawa, Takeaki, Hasegawa, Kiyoshi, Tachibana, Makoto, Shinkai, Yoichi, Koike, Kazuhiko
Publicado 2021

HNF1B‐driven three‐dimensional chromatin structure for molecular classification in pancreatic cancers

por Kato, Hiroyuki, Tateishi, Keisuke, Iwadate, Dosuke, Yamamoto, Keisuke, Fujiwara, Hiroaki, Nakatsuka, Takuma, Kudo, Yotaro, Hayakawa, Yoku, Ijichi, Hideaki, Otsuka, Motoyuki, Kishikawa, Takahiro, Takahashi, Ryota, Miyabayashi, Koji, Nakai, Yousuke, Hirata, Yoshihiro, Toyoda, Atsushi, Morishita, Shinichi, Fujishiro, Mitsuhiro
Publicado 2022

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

por Ikenoue, Tsuneo, Terakado, Yumi, Nakagawa, Hayato, Hikiba, Yohko, Fujii, Tomoaki, Matsubara, Daisuke, Noguchi, Rei, Zhu, Chi, Yamamoto, Keisuke, Kudo, Yotaro, Asaoka, Yoshinari, Yamaguchi, Kiyoshi, Ijichi, Hideaki, Tateishi, Keisuke, Fukushima, Noriyoshi, Maeda, Shin, Koike, Kazuhiko, Furukawa, Yoichi
Publicado 2016

Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

por Ikenoue, Tsuneo, Terakado, Yumi, Nakagawa, Hayato, Hikiba, Yohko, Fujii, Tomoaki, Matsubara, Daisuke, Noguchi, Rei, Zhu, Chi, Yamamoto, Keisuke, Kudo, Yotaro, Asaoka, Yoshinari, Yamaguchi, Kiyoshi, Ijichi, Hideaki, Tateishi, Keisuke, Fukushima, Noriyoshi, Maeda, Shin, Koike, Kazuhiko, Furukawa, Yoichi
Publicado 2017

TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma

por Shirai, Kiyokazu, Nagae, Genta, Seki, Motoaki, Kudo, Yotaro, Kamio, Asuka, Hayashi, Akimasa, Okabe, Atsushi, Ota, Satoshi, Tsutsumi, Shuichi, Fujita, Takanori, Yamamoto, Shogo, Nakaki, Ryo, Kanki, Yasuharu, Osawa, Tsuyoshi, Midorikawa, Yutaka, Tateishi, Keisuke, Ichinose, Masao, Aburatani, Hiroyuki
Publicado 2021

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer

por Yamamoto, Keisuke, Tateishi, Keisuke, Kudo, Yotaro, Hoshikawa, Mayumi, Tanaka, Mariko, Nakatsuka, Takuma, Fujiwara, Hiroaki, Miyabayashi, Koji, Takahashi, Ryota, Tanaka, Yasuo, Ijichi, Hideaki, Nakai, Yousuke, Isayama, Hiroyuki, Morishita, Yasuyuki, Aoki, Taku, Sakamoto, Yoshihiro, Hasegawa, Kiyoshi, Kokudo, Norihiro, Fukayama, Masashi, Koike, Kazuhiko
Publicado 2016

Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer

por Takahashi, Ryota, Ijichi, Hideaki, Sano, Makoto, Miyabayashi, Koji, Mohri, Dai, Kim, Jinsuk, Kimura, Gen, Nakatsuka, Takuma, Fujiwara, Hiroaki, Yamamoto, Keisuke, Kudo, Yotaro, Tanaka, Yasuo, Tateishi, Keisuke, Nakai, Yousuke, Morishita, Yasuyuki, Soma, Katsura, Takeda, Norihiko, Moses, Harold L., Isayama, Hiroyuki, Koike, Kazuhiko
Publicado 2020

Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation

por Fujiwara, Hiroaki, Tateishi, Keisuke, Misumi, Kento, Hayashi, Akimasa, Igarashi, Kaori, Kato, Hiroyuki, Nakatsuka, Takuma, Suzuki, Nobumi, Yamamoto, Keisuke, Kudo, Yotaro, Hayakawa, Yoku, Nakagawa, Hayato, Tanaka, Yasuo, Ijichi, Hideaki, Kogure, Hirofumi, Nakai, Yosuke, Isayama, Hiroyuki, Hasegawa, Kiyoshi, Fukayama, Masashi, Soga, Tomoyoshi, Koike, Kazuhiko
Publicado 2019

Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis

por Kawamura, Satoshi, Matsushita, Yuki, Kurosaki, Shigeyuki, Tange, Mizuki, Fujiwara, Naoto, Hayata, Yuki, Hayakawa, Yoku, Suzuki, Nobumi, Hata, Masahiro, Tsuboi, Mayo, Kishikawa, Takahiro, Kinoshita, Hiroto, Nakatsuka, Takuma, Sato, Masaya, Kudo, Yotaro, Hoshida, Yujin, Umemura, Atsushi, Eguchi, Akiko, Ikenoue, Tsuneo, Hirata, Yoshihiro, Uesugi, Motonari, Tateishi, Ryosuke, Tateishi, Keisuke, Fujishiro, Mitsuhiro, Koike, Kazuhiko, Nakagawa, Hayato
Publicado 2022