Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells

por Ohira, Takahito, Yoshimura, Kaho, Kugoh, Hiroyuki
Publicado 2023

Studies of Tumor Suppressor Genes via Chromosome Engineering

por Kugoh, Hiroyuki, Ohira, Takahito, Oshimura, Mitsuo
Publicado 2015

PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes

por Ohira, Takahito, Nakagawa, Suguru, Takeshita, Jumpei, Aburatani, Hiroyuki, Kugoh, Hiroyuki
Publicado 2021

Subchromosomal Mapping of a Putative Transformation Suppressor Gene on Human Chromosome 1

por Horikawa, Izumi, Yamada, Hideto, Kugoh, Hiroyuki, Yuasa, Yoshihiro, Suzuki, Mikio, Oshimura, Mitsuo
Publicado 1995

MTA1, a metastasis-associated protein, in endothelial cells is an essential molecule for angiogenesis

por Ishikawa, Mizuho, Osaki, Mitsuhiko, Uno, Narumi, Ohira, Takahito, Kugoh, Hiroyuki, Okada, Futoshi
Publicado 2022

miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells

por Ohira, Takahito, Naohiro, Sunamura, Nakayama, Yuji, Osaki, Mitsuhiko, Okada, Futoshi, Oshimura, Mitsuo, Kugoh, Hiroyuki
Publicado 2015

An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells

por Ohira, Takahito, Miyauchi, Koichi, Uno, Narumi, Shimizu, Noriaki, Kazuki, Yasuhiro, Oshimura, Mitsuo, Kugoh, Hiroyuki
Publicado 2019

Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes

por Nawata, Hisakatsu, Kashino, Genro, Tano, Keizo, Daino, Kazuhiro, Shimada, Yoshiya, Kugoh, Hiroyuki, Oshimura, Mitsuo, Watanabe, Masami
Publicado 2011

PITX1 is a reliable biomarker for predicting prognosis in patients with oral epithelial dysplasia

por NAKABAYASHI, MOTOKI, OSAKI, MITSUHIKO, KODANI, ISAMU, OKADA, FUTOSHI, RYOKE, KAZUO, OSHIMURA, MITSUO, ITO, HISAO, KUGOH, HIROYUKI
Publicado 2014

Regulation of functional KCNQ1OT1 lncRNA by β-catenin

por Sunamura, Naohiro, Ohira, Takahito, Kataoka, Miki, Inaoka, Daigo, Tanabe, Hideyuki, Nakayama, Yuji, Oshimura, Mitsuo, Kugoh, Hiroyuki
Publicado 2016

Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation

por Yoshimura, Yuki, Nakamura, Kazuomi, Endo, Takeshi, Kajitani, Naoyo, Kazuki, Kanako, Kazuki, Yasuhiro, Kugoh, Hiroyuki, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Publicado 2015

Real‐time fluorometric evaluation of hepatoblast proliferation in vivo and in vitro using the expression of CYP3A7 coding for human fetus‐specific P450

por Okuyama, Shota, Kawamura, Fumihiko, Kubiura, Musashi, Tsuji, Saori, Osaki, Mitsuhiko, Kugoh, Hiroyuki, Oshimura, Mitsuo, Kazuki, Yasuhiro, Tada, Masako
Publicado 2020

PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription

por Ohira, Takahito, Kojima, Hirotada, Kuroda, Yuko, Aoki, Sayaka, Inaoka, Daigo, Osaki, Mitsuhiko, Wanibuchi, Hideki, Okada, Futoshi, Oshimura, Mitsuo, Kugoh, Hiroyuki
Publicado 2019

Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering

por Abe, Satoshi, Tanaka, Hiromi, Notsu, Tomomi, Horike, Shin-ichi, Fujisaki, Chikako, Qi, Dong-Lai, Ohhira, Takahito, Gilley, David, Oshimura, Mitsuo, Kugoh, Hiroyuki
Publicado 2010

Activation of PPARγ in bladder cancer via introduction of the long arm of human chromosome 9

por Shimizu, Ryutaro, Ohira, Takahito, Yagyu, Takuki, Yumioka, Tetsuya, Yamaguchi, Noriya, Iwamoto, Hideto, Morizane, Shuichi, Hikita, Katsuya, Honda, Masashi, Takenaka, Atsushi, Kugoh, Hiroyuki
Publicado 2022

Human chromosome 3p21.3 carries TERT transcriptional regulators in pancreatic cancer

por Yagyu, Takuki, Ohira, Takahito, Shimizu, Ryutaro, Morimoto, Masaki, Murakami, Yuki, Hanaki, Takehiko, Kihara, Kyoichi, Matsunaga, Tomoyuki, Yamamoto, Manabu, Tokuyasu, Naruo, Sakamoto, Teruhisa, Fujiwara, Yoshiyuki, Kugoh, Hiroyuki
Publicado 2021

Establishment of an antibody specific for AMIGO2 improves immunohistochemical evaluation of liver metastases and clinical outcomes in patients with colorectal cancer

por Goto, Keisuke, Osaki, Mitsuhiko, Izutsu, Runa, Tanaka, Hiroshi, Sasaki, Ryo, Tanio, Akimitsu, Satofuka, Hiroyuki, Kazuki, Yasuhiro, Yamamoto, Manabu, Kugoh, Hiroyuki, Ito, Hisao, Oshimura, Mitsuo, Fujiwara, Yoshiyuki, Okada, Futoshi
Publicado 2022

CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome

por Asamitsu, Sefan, Yabuki, Yasushi, Ikenoshita, Susumu, Kawakubo, Kosuke, Kawasaki, Moe, Usuki, Shingo, Nakayama, Yuji, Adachi, Kaori, Kugoh, Hiroyuki, Ishii, Kazuhiro, Matsuura, Tohru, Nanba, Eiji, Sugiyama, Hiroshi, Fukunaga, Kohji, Shioda, Norifumi
Publicado 2021

Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate

por Satofuka, Hiroyuki, Wang, Yayan, Yamazaki, Kyotaro, Hamamichi, Shusei, Fukuhara, Takeshi, Rafique, Abdur, Osako, Nana, Kanazawa, Iori, Endo, Takeshi, Miyake, Naomi, Honma, Kazuhisa, Nagashima, Yuichi, Hichiwa, Genki, Shimoya, Kazuto, Abe, Satoshi, Moriwaki, Takashi, Murakami, Yasufumi, Gao, Xu, Kugoh, Hiroyuki, Oshimura, Mitsuo, Ito, Yuji, Kazuki, Yasuhiro
Publicado 2023