RosettaDesign server for protein design

por Liu, Yi, Kuhlman, Brian
Publicado 2006

Anchored Design of Protein-Protein Interfaces

por Lewis, Steven M., Kuhlman, Brian A.
Publicado 2011

Transfer learning to leverage larger datasets for improved prediction of protein stability changes

por Dieckhaus, Henry, Brocidiacono, Michael, Randolph, Nicholas, Kuhlman, Brian
Publicado 2023

De novo design of stable proteins that efficaciously inhibit oncogenic G proteins

por Cummins, Matthew C., Tripathy, Ashutosh, Sondek, John, Kuhlman, Brian
Publicado 2023

A Generic Program for Multistate Protein Design

por Leaver-Fay, Andrew, Jacak, Ron, Stranges, P. Benjamin, Kuhlman, Brian
Publicado 2011

Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design

por Renfrew, P. Douglas, Choi, Eun Jung, Bonneau, Richard, Kuhlman, Brian
Publicado 2012

SwiftLib: rapid degenerate-codon-library optimization through dynamic programming

por Jacobs, Timothy M., Yumerefendi, Hayretin, Kuhlman, Brian, Leaver-Fay, Andrew
Publicado 2015

In silico evolution of protein binders with deep learning models for structure prediction and sequence design

por Goudy, Odessa J, Nallathambi, Amrita, Kinjo, Tomoaki, Randolph, Nicholas, Kuhlman, Brian
Publicado 2023

Data in support of UbSRD: The Ubiquitin Structural Relational Database

por Harrison, Joseph S., Jacobs, Tim M., Houlihan, Kevin, Van Doorslaer, Koenraad, Kuhlman, Brian
Publicado 2015

Designer proteins that competitively inhibit Gα(q) by targeting its effector site

por Hussain, Mahmud, Cummins, Matthew C., Endo-Streeter, Stuart, Sondek, John, Kuhlman, Brian
Publicado 2021

Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker

por Adikes, Rebecca C., Hallett, Ryan A., Saway, Brian F., Kuhlman, Brian, Slep, Kevin C.
Publicado 2018

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

por Vaughan, Robert M, Dickson, Bradley M, Cornett, Evan M, Harrison, Joseph S, Kuhlman, Brian, Rothbart, Scott B
Publicado 2018

A genetically-encoded photoactivatable Rac controls the motility of living cells

por Wu, Yi I., Frey, Daniel, Lungu, Oana I., Jaehrig, Angelika, Schlichting, Ilme, Kuhlman, Brian, Hahn, Klaus M.
Publicado 2009

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications

por Yumerefendi, Hayretin, Lerner, Andrew Michael, Zimmerman, Seth Parker, Hahn, Klaus, Bear, James E, Strahl, Brian D., Kuhlman, Brian
Publicado 2016

Control of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear Translocation

por Yumerefendi, Hayretin, Dickinson, Daniel J., Wang, Hui, Zimmerman, Seth P., Bear, James E., Goldstein, Bob, Hahn, Klaus, Kuhlman, Brian
Publicado 2015

Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability

por Der, Bryan S., Kluwe, Christien, Miklos, Aleksandr E., Jacak, Ron, Lyskov, Sergey, Gray, Jeffrey J., Georgiou, George, Ellington, Andrew D., Kuhlman, Brian
Publicado 2013

Requirements for 5′dRP/AP lyase activity in Ku

por Strande, Natasha T., Carvajal-Garcia, Juan, Hallett, Ryan A., Waters, Crystal A., Roberts, Steven A., Strom, Christina, Kuhlman, Brian, Ramsden, Dale A.
Publicado 2014

Labelling and optical erasure of synaptic memory traces in the motor cortex

por Hayashi-Takagi, Akiko, Yagishita, Sho, Nakamura, Mayumi, Shirai, Fukutoshi, Wu, Yi, Loshbaugh, Amanda L., Kuhlman, Brian, Hahn, Klaus M., Kasai, Haruo
Publicado 2015

LOVTRAP, An Optogenetic System for Photo-induced Protein Dissociation

por Wang, Hui, Vilela, Marco, Winkler, Andreas, Tarnawski, Miroslaw, Schlichting, Ilme, Yumerefendi, Hayretin, Kuhlman, Brian, Liu, Rihe, Danuser, Gaudenz, Hahn, Klaus M
Publicado 2016

A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines

por Phan, Thanh T.N., Hvasta, Matthew G., Kudlacek, Stephan T., Thiono, Devina J., Tripathy, Ashutosh, Nicely, Nathan I., de Silva, Aravinda M., Kuhlman, Brian
Publicado 2022