Determination of the Proteolytic Cleavage Sites of the Amyloid Precursor-Like Protein 2 by the Proteases ADAM10, BACE1 and γ-Secretase

por Hogl, Sebastian, Kuhn, Peer-Hendrik, Colombo, Alessio, Lichtenthaler, Stefan F.
Publicado 2011

Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer’s Disease

por Höfling, Corinna, Shehabi, Emira, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F., Hartlage-Rübsamen, Maike, Roßner, Steffen
Publicado 2019

Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

por Augustin, Regina, Endres, Kristina, Reinhardt, Sven, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Hansen, Jens, Wurst, Wolfgang, Trümbach, Dietrich
Publicado 2012

QARIP: a web server for quantitative proteomic analysis of regulated intramembrane proteolysis

por Ivankov, Dmitry N., Bogatyreva, Natalya S., Hönigschmid, Peter, Dislich, Bastian, Hogl, Sebastian, Kuhn, Peer-Hendrik, Frishman, Dmitrij, Lichtenthaler, Stefan F.
Publicado 2013

Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance

por Duernberger, Yvonne, Liu, Shu, Riemschoss, Katrin, Paulsen, Lydia, Bester, Romina, Kuhn, Peer-Hendrik, Schölling, Manuel, Lichtenthaler, Stefan F., Vorberg, Ina
Publicado 2018

Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression

por Bartels, Martin, Weckbecker, Daniel, Kuhn, Peer-Hendrik, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Lichtenthaler, Stefan F., Bötzel, Kai, Giese, Armin
Publicado 2019

Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain

por Heiland, Tina, Zeitschel, Ulrike, Puchades, Maja A., Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F., Bjaalie, Jan G., Hartlage‐Rübsamen, Maike, Roßner, Steffen, Höfling, Corinna
Publicado 2018

Generation and deposition of Aβ43 by the virtually inactive presenilin‐1 L435F mutant contradicts the presenilin loss‐of‐function hypothesis of Alzheimer's disease

por Kretner, Benedikt, Trambauer, Johannes, Fukumori, Akio, Mielke, Janina, Kuhn, Peer‐Hendrik, Kremmer, Elisabeth, Giese, Armin, Lichtenthaler, Stefan F, Haass, Christian, Arzberger, Thomas, Steiner, Harald
Publicado 2016

PERK activation mitigates tau pathology in vitro and in vivo

por Bruch, Julius, Xu, Hong, Rösler, Thomas W, De Andrade, Anderson, Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F, Arzberger, Thomas, Winklhofer, Konstanze F, Müller, Ulrich, Höglinger, Günter U
Publicado 2017

Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation

por Hartlage-Rübsamen, Maike, Bluhm, Alexandra, Piechotta, Anke, Linnert, Miriam, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Lues, Inge, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F., Roßner, Steffen, Höfling, Corinna
Publicado 2018

The Fibrin Matrix Regulates Angiogenic Responses within the Hemostatic Microenvironment through Biochemical Control

por Hadjipanayi, Ektoras, Kuhn, Peer-Hendrik, Moog, Philipp, Bauer, Anna-Theresa, Kuekrek, Haydar, Mirzoyan, Lilit, Hummel, Anja, Kirchhoff, Katharina, Salgin, Burak, Isenburg, Sarah, Dornseifer, Ulf, Ninkovic, Milomir, Machens, Hans-Günther, Schilling, Arndt F.
Publicado 2015

QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain

por Yates, Sharon C., Groeneboom, Nicolaas E., Coello, Christopher, Lichtenthaler, Stefan F., Kuhn, Peer-Hendrik, Demuth, Hans-Ulrich, Hartlage-Rübsamen, Maike, Roßner, Steffen, Leergaard, Trygve, Kreshuk, Anna, Puchades, Maja A., Bjaalie, Jan G.
Publicado 2019

The immunologic tumor microenvironment in endometrioid endometrial cancer in the morphomolecular context: mutual correlations and prognostic impact depending on molecular alteratio...

por Willvonseder, Barbara, Stögbauer, Fabian, Steiger, Katja, Jesinghaus, Moritz, Kuhn, Peer-Hendrik, Brambs, Christine, Engel, Jutta, Bronger, Holger, Schmidt, Georg Philipp, Haller, Bernhard, Weichert, Wilko, Keller, Gisela, Noske, Aurelia, Pfarr, Nicole, Boxberg, Melanie
Publicado 2020

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

por Kuhn, Peer-Hendrik, Colombo, Alessio Vittorio, Schusser, Benjamin, Dreymueller, Daniela, Wetzel, Sebastian, Schepers, Ute, Herber, Julia, Ludwig, Andreas, Kremmer, Elisabeth, Montag, Dirk, Müller, Ulrike, Schweizer, Michaela, Saftig, Paul, Bräse, Stefan, Lichtenthaler, Stefan F
Publicado 2016

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons

por Pigoni, Martina, Wanngren, Johanna, Kuhn, Peer-Hendrik, Munro, Kathryn M., Gunnersen, Jenny M., Takeshima, Hiroshi, Feederle, Regina, Voytyuk, Iryna, De Strooper, Bart, Levasseur, Mikail D., Hrupka, Brian J., Müller, Stephan A., Lichtenthaler, Stefan F.
Publicado 2016

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodies

por Höfling, Corinna, Morawski, Markus, Zeitschel, Ulrike, Zanier, Elisa R., Moschke, Katrin, Serdaroglu, Alperen, Canneva, Fabio, von Hörsten, Stephan, De Simoni, Maria‐Grazia, Forloni, Gianluigi, Jäger, Carsten, Kremmer, Elisabeth, Roßner, Steffen, Lichtenthaler, Stefan F., Kuhn, Peer‐Hendrik
Publicado 2016

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains

por Causevic, Mirsada, Dominko, Kristina, Malnar, Martina, Vidatic, Lea, Cermak, Stjepko, Pigoni, Martina, Kuhn, Peer-Hendrik, Colombo, Alessio, Havas, Daniel, Flunkert, Stefanie, McDonald, Jessica, Gunnersen, Jenny M., Hutter-Paier, Birgit, Tahirovic, Sabina, Windisch, Manfred, Krainc, Dimitri, Lichtenthaler, Stefan F., Hecimovic, Silva
Publicado 2018

Pre-operative cellular dissociation grading in biopsies is highly predictive of post-operative tumour stage and patient outcome in head and neck squamous cell carcinoma

por Jesinghaus, Moritz, Steiger, Katja, Stögbauer, Fabian, Haller, Bernhard, Kolk, Andreas, Straßen, Ulrich, Pickhard, Anja, Wirth, Markus, Silva, Miguel, Budczies, Jan, Becker von Rose, Aaron, Konukiewitz, Björn, Kuhn, Peer, Klinghammer, Konrad, Dapper, Hendrik, Münch, Stefan, Combs, Stephanie E., Weichert, Wilko, Boxberg, Melanie
Publicado 2020

TDP‐43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons

por Schwenk, Benjamin M, Hartmann, Hannelore, Serdaroglu, Alperen, Schludi, Martin H, Hornburg, Daniel, Meissner, Felix, Orozco, Denise, Colombo, Alessio, Tahirovic, Sabina, Michaelsen, Meike, Schreiber, Franziska, Haupt, Simone, Peitz, Michael, Brüstle, Oliver, Küpper, Clemens, Klopstock, Thomas, Otto, Markus, Ludolph, Albert C, Arzberger, Thomas, Kuhn, Peer‐Hendrik, Edbauer, Dieter
Publicado 2016

γ-secretase directly sheds the survival receptor BCMA from plasma cells

por Laurent, Sarah A., Hoffmann, Franziska S., Kuhn, Peer-Hendrik, Cheng, Qingyu, Chu, Yuanyuan, Schmidt-Supprian, Marc, Hauck, Stefanie M., Schuh, Elisabeth, Krumbholz, Markus, Rübsamen, Heike, Wanngren, Johanna, Khademi, Mohsen, Olsson, Tomas, Alexander, Tobias, Hiepe, Falk, Pfister, Hans-Walter, Weber, Frank, Jenne, Dieter, Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F., Meinl, Edgar
Publicado 2015