Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay

por Shafer-Weaver, Kimberly A, Sayers, Thomas, Kuhns, Douglas B, Strobl, Susan L, Burkett, Mark W, Baseler, Michael, Malyguine, Anatoli
Publicado 2004

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

por Davies, Luke C., Rice, Christopher M., Palmieri, Erika M., Taylor, Philip R., Kuhns, Douglas B., McVicar, Daniel W.
Publicado 2017

Neutrophil activation in systemic capillary leak syndrome (Clarkson disease)

por Xie, Zhihui, Kuhns, Douglas B., Gu, Xuesong, Otu, Hasan H., Libermann, Towia A., Gallin, John I., Parikh, Samir M., Druey, Kirk M.
Publicado 2019

Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections

por Medvedev, Andrei E., Lentschat, Arnd, Kuhns, Douglas B., Blanco, Jorge C.G., Salkowski, Cindy, Zhang, Shuling, Arditi, Moshe, Gallin, John I., Vogel, Stefanie N.
Publicado 2003

Homozygous variant p. Arg90His in NCF1 is associated with early-onset Interferonopathy: a case report

por Schnappauf, Oskar, Heale, Liane, Dissanayake, Dilan, Tsai, Wanxia L., Gadina, Massimo, Leto, Thomas L., Kastner, Daniel L., Malech, Harry L., Kuhns, Douglas B., Aksentijevich, Ivona, Laxer, Ronald M.
Publicado 2021

Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47(phox)

por Sowrirajan, Bharatwaj, Saito, Yoshiro, Poudyal, Deepak, Chen, Qian, Sui, Hongyan, DeRavin, Suk See, Imamichi, Hiromi, Sato, Toyotaka, Kuhns, Douglas B., Noguchi, Noriko, Malech, Harry L., Lane, H. Clifford, Imamichi, Tomozumi
Publicado 2017

Colitis susceptibility in p47(phox−/−) mice is mediated by the microbiome

por Falcone, E. Liana, Abusleme, Loreto, Swamydas, Muthulekha, Lionakis, Michail S., Ding, Li, Hsu, Amy P., Zelazny, Adrian M., Moutsopoulos, Niki M., Kuhns, Douglas B., Deming, Clay, Quiñones, Mariam, Segre, Julia A., Bryant, Clare E., Holland, Steven M.
Publicado 2016

A phase III randomized crossover trial of plerixafor versus G-CSF for treatment of WHIM syndrome

por McDermott, David H., Velez, Daniel, Cho, Elena, Cowen, Edward W., DiGiovanna, John J., Pastrana, Diana V., Buck, Christopher B., Calvo, Katherine R., Gardner, Pamela J., Rosenzweig, Sergio D., Stratton, Pamela, Merideth, Melissa A., Kim, H. Jeffrey, Brewer, Carmen, Katz, James D., Kuhns, Douglas B., Malech, Harry L., Follmann, Dean, Fay, Michael P., Murphy, Philip M.
Publicado 2023

Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology

por Takeda, Andrew J., Maher, Timothy J., Zhang, Yu, Lanahan, Stephen M., Bucklin, Molly L., Compton, Susan R., Tyler, Paul M., Comrie, William A., Matsuda, Makoto, Olivier, Kenneth N., Pittaluga, Stefania, McElwee, Joshua J., Long Priel, Debra A., Kuhns, Douglas B., Williams, Roger L., Mustillo, Peter J., Wymann, Matthias P., Koneti Rao, V., Lucas, Carrie L.
Publicado 2019

CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System

por Drummond, Rebecca A., Collar, Amanda L., Swamydas, Muthulekha, Rodriguez, Carlos A., Lim, Jean K., Mendez, Laura M., Fink, Danielle L., Hsu, Amy P., Zhai, Bing, Karauzum, Hatice, Mikelis, Constantinos M., Rose, Stacey R., Ferre, Elise M. N., Yockey, Lynne, Lemberg, Kimberly, Kuehn, Hye Sun, Rosenzweig, Sergio D., Lin, Xin, Chittiboina, Prashant, Datta, Sandip K., Belhorn, Thomas H., Weimer, Eric T., Hernandez, Michelle L., Hohl, Tobias M., Kuhns, Douglas B., Lionakis, Michail S.
Publicado 2015

Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19

por Liu, Can, Martins, Andrew J., Lau, William W., Rachmaninoff, Nicholas, Chen, Jinguo, Imberti, Luisa, Mostaghimi, Darius, Fink, Danielle L., Burbelo, Peter D., Dobbs, Kerry, Delmonte, Ottavia M., Bansal, Neha, Failla, Laura, Sottini, Alessandra, Quiros-Roldan, Eugenia, Han, Kyu Lee, Sellers, Brian A., Cheung, Foo, Sparks, Rachel, Chun, Tae-Wook, Moir, Susan, Lionakis, Michail S., Rossi, Camillo, Su, Helen C., Kuhns, Douglas B., Cohen, Jeffrey I., Notarangelo, Luigi D., Tsang, John S.
Publicado 2021

Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling

por Nunes-Santos, Cristiane J., Kuehn, HyeSun, Boast, Brigette, Hwang, SuJin, Kuhns, Douglas B., Stoddard, Jennifer, Niemela, Julie E., Fink, Danielle L., Pittaluga, Stefania, Abu-Asab, Mones, Davies, John S., Barr, Valarie A., Kawai, Tomoki, Delmonte, Ottavia M., Bosticardo, Marita, Garofalo, Mary, Carneiro-Sampaio, Magda, Somech, Raz, Gharagozlou, Mohammad, Parvaneh, Nima, Samelson, Lawrence E., Fleisher, Thomas A., Puel, Anne, Notarangelo, Luigi D., Boisson, Bertrand, Casanova, Jean-Laurent, Derfalvi, Beata, Rosenzweig, Sergio D.
Publicado 2023

Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn syndrome

por Rigoni, Rosita, Fontana, Elena, Dobbs, Kerry, Marrella, Veronica, Taverniti, Valentina, Maina, Virginia, Facoetti, Amanda, D’Amico, Giovanna, Al-Herz, Waleed, Cruz-Munoz, Mario Ernesto, Schuetz, Catharina, Gennery, Andrew R., Garabedian, Elizabeth K., Giliani, Silvia, Draper, Deborah, Dbaibo, Ghassan, Geha, Raif S., Meyts, Isabelle, Tousseyn, Thomas, Neven, Benedicte, Moshous, Despina, Fischer, Alain, Schulz, Ansgar, Finocchi, Andrea, Kuhns, Douglas B., Fink, Danielle L., Lionakis, Michail S., Swamydas, Muthulekha, Guglielmetti, Simone, Alejo, Julie, Myles, Ian A., Pittaluga, Stefania, Notarangelo, Luigi D., Villa, Anna, Cassani, Barbara
Publicado 2020

Immunogenetics associated with severe coccidioidomycosis

por Hsu, Amy P., Korzeniowska, Agnieszka, Aguilar, Cynthia C., Gu, Jingwen, Karlins, Eric, Oler, Andrew J., Chen, Gang, Reynoso, Glennys V., Davis, Joie, Chaput, Alexandria, Peng, Tao, Sun, Ling, Lack, Justin B., Bays, Derek J., Stewart, Ethan R., Waldman, Sarah E., Powell, Daniel A., Donovan, Fariba M., Desai, Jigar V., Pouladi, Nima, Long Priel, Debra A., Yamanaka, Daisuke, Rosenzweig, Sergio D., Niemela, Julie E., Stoddard, Jennifer, Freeman, Alexandra F., Zerbe, Christa S., Kuhns, Douglas B., Lussier, Yves A., Olivier, Kenneth N., Boucher, Richard C., Hickman, Heather D., Frelinger, Jeffrey, Fierer, Joshua, Shubitz, Lisa F., Leto, Thomas L., Thompson, George R., Galgiani, John N., Lionakis, Michail S., Holland, Steven M.
Publicado 2022

Characterization of the antispike IgG immune response to COVID-19 vaccines in people with a wide variety of immunodeficiencies

por Zendt, Mackenzie, Bustos Carrillo, Fausto A., Kelly, Sophie, Saturday, Taylor, DeGrange, Maureen, Ginigeme, Anita, Wu, Lurline, Callier, Viviane, Ortega-Villa, Ana, Faust, Mondreakest, Chang-Rabley, Emma, Bugal, Kara, Kenney, Heather, Khil, Pavel, Youn, Jung-Ho, Osei, Gloria, Regmi, Pravesh, Anderson, Victoria, Bosticardo, Marita, Daub, Janine, DiMaggio, Thomas, Kreuzburg, Samantha, Pala, Francesca, Pfister, Justina, Treat, Jennifer, Ulrick, Jean, Karkanitsa, Maria, Kalish, Heather, Kuhns, Douglas B., Priel, Debra L., Fink, Danielle L., Tsang, John S., Sparks, Rachel, Uzel, Gulbu, Waldman, Meryl A., Zerbe, Christa S., Delmonte, Ottavia M., Bergerson, Jenna R. E., Das, Sanchita, Freeman, Alexandra F., Lionakis, Michail S., Sadtler, Kaitlyn, van Doremalen, Neeltje, Munster, Vincent, Notarangelo, Luigi D., Holland, Steven M., Ricotta, Emily E.
Publicado 2023

An immune-based biomarker signature is associated with mortality in COVID-19 patients

por Abers, Michael S., Delmonte, Ottavia M., Ricotta, Emily E., Fintzi, Jonathan, Fink, Danielle L., de Jesus, Adriana A. Almeida, Zarember, Kol A., Alehashemi, Sara, Oikonomou, Vasileios, Desai, Jigar V., Canna, Scott W., Shakoory, Bita, Dobbs, Kerry, Imberti, Luisa, Sottini, Alessandra, Quiros-Roldan, Eugenia, Castelli, Francesco, Rossi, Camillo, Brugnoni, Duilio, Biondi, Andrea, Bettini, Laura Rachele, D’Angio’, Mariella, Bonfanti, Paolo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Gliniewicz, Emily F., Shaw, Elana, Kahle, Dana E., Rastegar, Andre T., Stack, Michael, Myint-Hpu, Katherine, Levinson, Susan L., DiNubile, Mark J., Chertow, Daniel W., Burbelo, Peter D., Cohen, Jeffrey I., Calvo, Katherine R., Tsang, John S., Su, Helen C., Gallin, John I., Kuhns, Douglas B., Goldbach-Mansky, Raphaela, Lionakis, Michail S., Notarangelo, Luigi D.
Publicado 2021

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome

por de Jesus, Adriana A., Chen, Guibin, Yang, Dan, Brdicka, Tomas, Ruth, Natasha M., Bennin, David, Cebecauerova, Dita, Malcova, Hana, Freeman, Helen, Martin, Neil, Svojgr, Karel, Passo, Murray H., Bhuyan, Farzana, Alehashemi, Sara, Rastegar, Andre T., Uss, Katsiaryna, Kardava, Lela, Marrero, Bernadette, Duric, Iris, Omoyinmi, Ebun, Peldova, Petra, Lee, Chyi-Chia Richard, Kleiner, David E., Hadigan, Colleen M., Hewitt, Stephen M., Pittaluga, Stefania, Carmona-Rivera, Carmelo, Calvo, Katherine R., Shah, Nirali, Balascakova, Miroslava, Fink, Danielle L., Kotalova, Radana, Parackova, Zuzana, Peterkova, Lucie, Kuzilkova, Daniela, Campr, Vit, Sramkova, Lucie, Biancotto, Angelique, Brooks, Stephen R., Manes, Cameron, Meffre, Eric, Harper, Rebecca L., Kuehn, Hyesun, Kaplan, Mariana J., Brogan, Paul, Rosenzweig, Sergio D., Merchant, Melinda, Deng, Zuoming, Huttenlocher, Anna, Moir, Susan L., Kuhns, Douglas B., Boehm, Manfred, Skvarova Kramarzova, Karolina, Goldbach-Mansky, Raphaela
Publicado 2023

Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

por Carmona-Rivera, Carmelo, Zhang, Yu, Dobbs, Kerry, Markowitz, Tovah E., Dalgard, Clifton L., Oler, Andrew J., Claybaugh, Dillon R., Draper, Deborah, Truong, Meng, Delmonte, Ottavia M., Licciardi, Francesco, Ramenghi, Ugo, Crescenzio, Nicoletta, Imberti, Luisa, Sottini, Alessandra, Quaresima, Virginia, Fiorini, Chiara, Discepolo, Valentina, Lo Vecchio, Andrea, Guarino, Alfredo, Pierri, Luca, Catzola, Andrea, Biondi, Andrea, Bonfanti, Paolo, Poli Harlowe, Maria C., Espinosa, Yasmin, Astudillo, Camila, Rey-Jurado, Emma, Vial, Cecilia, de la Cruz, Javiera, Gonzalez, Ricardo, Pinera, Cecilia, Mays, Jacqueline W., Ng, Ashley, Platt, Andrew, Drolet, Beth, Moon, John, Cowen, Edward W., Kenney, Heather, Weber, Sarah E., Castagnoli, Riccardo, Magliocco, Mary, Stack, Michael A., Montealegre, Gina, Barron, Karyl, Fink, Danielle L., Kuhns, Douglas B., Hewitt, Stephen M., Arkin, Lisa M., Chertow, Daniel S., Su, Helen C., Notarangelo, Luigi D., Kaplan, Mariana J.
Publicado 2022

Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis

por Drummond, Rebecca A., Desai, Jigar V., Hsu, Amy P., Oikonomou, Vasileios, Vinh, Donald C., Acklin, Joshua A., Abers, Michael S., Walkiewicz, Magdalena A., Anzick, Sarah L., Swamydas, Muthulekha, Vautier, Simon, Natarajan, Mukil, Oler, Andrew J., Yamanaka, Daisuke, Mayer-Barber, Katrin D., Iwakura, Yoichiro, Bianchi, David, Driscoll, Brian, Hauck, Ken, Kline, Ahnika, Viall, Nicholas S.P., Zerbe, Christa S., Ferré, Elise M.N., Schmitt, Monica M., DiMaggio, Tom, Pittaluga, Stefania, Butman, John A., Zelazny, Adrian M., Shea, Yvonne R., Arias, Cesar A., Ashbaugh, Cameron, Mahmood, Maryam, Temesgen, Zelalem, Theofiles, Alexander G., Nigo, Masayuki, Moudgal, Varsha, Bloch, Karen C., Kelly, Sean G., Whitworth, M. Suzanne, Rao, Ganesh, Whitener, Cindy J., Mafi, Neema, Gea-Banacloche, Juan, Kenyon, Lawrence C., Miller, William R., Boggian, Katia, Gilbert, Andrea, Sincock, Matthew, Freeman, Alexandra F., Bennett, John E., Hasbun, Rodrigo, Mikelis, Constantinos M., Kwon-Chung, Kyung J., Belkaid, Yasmine, Brown, Gordon D., Lim, Jean K., Kuhns, Douglas B., Holland, Steven M., Lionakis, Michail S.
Publicado 2022