The Future of Lipid-Lowering Therapy

por van Zwol, Willemien, Rimbert, Antoine, Kuivenhoven, Jan Albert
Publicado 2019

Managing of Dyslipidaemia Characterized by Accumulation of Triglyceride-Rich Lipoproteins

por Visser, Jolien, van Zwol, Willemien, Kuivenhoven, Jan Albert
Publicado 2022

Recycling the LDL receptor to combat atherosclerosis

por Vos, Dyonne, Kuivenhoven, Jan Albert, van de Sluis, Bart
Publicado 2018

Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles

por Zhang, Boyan, Kuipers, Folkert, de Boer, Jan Freark, Kuivenhoven, Jan Albert
Publicado 2021

Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females

por Zhang, Xiang, Rimbert, Antoine, Balder, Willem, Zwinderman, Aeilko Having, Kuivenhoven, Jan Albert, Dallinga-Thie, Geesje Margaretha, Groen, Albert Kornelis
Publicado 2018

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency

por Gomaraschi, Monica, Ossoli, Alice, Pozzi, Silvia, Nilsson, Peter, Cefalù, Angelo B., Averna, Maurizio, Kuivenhoven, Jan Albert, Hovingh, G. Kees, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura
Publicado 2014

Low Detection Rates of Genetic FH in Cohort of Patients With Severe Hypercholesterolemia in the United Arabic Emirates

por Rimbert, Antoine, Daggag, Hinda, Lansberg, Peter, Buckley, Adam, Viel, Martijn, Kanninga, Roan, Johansson, Lennart, Dullaart, Robin P. F., Sinke, Richard, Al Tikriti, Alia, Kuivenhoven, Jan Albert, Barakat, Maha Taysir
Publicado 2022

Male apoE*3‐Leiden.CETP mice on high‐fat high‐cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men

por Paalvast, Yared, Gerding, Albert, Wang, Yanan, Bloks, Vincent W., van Dijk, Theo H., Havinga, Rick, Willems van Dijk, Ko, Rensen, Patrick C. N., Bakker, Barbara M., Kuivenhoven, Jan Albert, Groen, Albert K.
Publicado 2017

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

por Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen, Debby P. Y., Hofker, Marten H.
Publicado 2015

Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

por Gruben, Nanda, Aparicio Vergara, Marcela, Kloosterhuis, Niels J., van der Molen, Henk, Stoelwinder, Stefan, Youssef, Sameh, de Bruin, Alain, Delsing, Dianne J., Kuivenhoven, Jan Albert, van de Sluis, Bart, Hofker, Marten H., Koonen, Debby P. Y.
Publicado 2014

Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor–Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) a...

por Oldoni, Federico, van Capelleveen, Julian C., Dalila, Nawar, Wolters, Justina C., Heeren, Joerg, Sinke, Richard J., Hui, David Y., Dallinga-Thie, Geesje M., Frikke-Schmidt, Ruth, Hovingh, Kees G., van de Sluis, Bart, Tybjærg-Hansen, Anne, Kuivenhoven, Jan Albert
Publicado 2018

Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings

por Norum, Kaare R., Remaley, Alan T., Miettinen, Helena E., Strøm, Erik H., Balbo, Bruno E. P., Sampaio, Carlos A. T .L., Wiig, Ingrid, Kuivenhoven, Jan Albert, Calabresi, Laura, Tesmer, John J., Zhou, Mingyue, Ng, Dominic S., Skeie, Bjørn, Karathanasis, Sotirios K., Manthei, Kelly A., Retterstøl, Kjetil
Publicado 2020

Lipoprotein(a) as a cardiovascular risk factor: current status

por Nordestgaard, Børge G., Chapman, M. John, Ray, Kausik, Borén, Jan, Andreotti, Felicita, Watts, Gerald F., Ginsberg, Henry, Amarenco, Pierre, Catapano, Alberico, Descamps, Olivier S., Fisher, Edward, Kovanen, Petri T., Kuivenhoven, Jan Albert, Lesnik, Philippe, Masana, Luis, Reiner, Zeljko, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Tybjærg-Hansen, Anne
Publicado 2010

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

por Chapman, M. John, Ginsberg, Henry N., Amarenco, Pierre, Andreotti, Felicita, Borén, Jan, Catapano, Alberico L., Descamps, Olivier S., Fisher, Edward, Kovanen, Petri T., Kuivenhoven, Jan Albert, Lesnik, Philippe, Masana, Luis, Nordestgaard, Børge G., Ray, Kausik K., Reiner, Zeljko, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Tybjærg-Hansen, Anne, Watts, Gerald F.
Publicado 2011

Reduced CETP glycosylation and activity in patients with homozygous B4GALT1 mutations

por van den Boogert, Marjolein A.W., Crunelle, Cleo L., Ali, Lubna, Larsen, Lars E., Kuil, Sacha D., Levels, Johannes H.M., Schimmel, Alinda W.M., Konstantopoulou, Vassiliki, Guerin, Maryse, Kuivenhoven, Jan Albert, Dallinga‐Thie, Geesje M., Stroes, Erik S.G., Lefeber, Dirk J., Holleboom, Adriaan G.
Publicado 2019

A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis

por Verzijl, Cristy R.C., Oldoni, Federico, Loaiza, Natalia, Wolters, Justina C., Rimbert, Antoine, Tian, E., Yang, Weiming, Struik, Dicky, Smit, Marieke, Kloosterhuis, Niels J., Fernandez, Amy J., Samara, Nadine L., Ten Hagen, Kelly G., Dalal, Kruti, Chernish, Aliona, McCluggage, Peggy, Tabak, Lawrence A., Jonker, Johan W., Kuivenhoven, Jan Albert
Publicado 2022

Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans

por Loaiza, Natalia, Hartgers, Merel L., Reeskamp, Laurens F., Balder, Jan-Willem, Rimbert, Antoine, Bazioti, Venetia, Wolters, Justina C., Winkelmeijer, Maaike, Jansen, Hans P.G., Dallinga-Thie, Geesje M., Volta, Andrea, Huijkman, Nicolette, Smit, Marieke, Kloosterhuis, Niels, Koster, Mirjam, Svendsen, Arthur F., van de Sluis, Bart, Hovingh, G. Kees, Grefhorst, Aldo, Kuivenhoven, Jan Albert
Publicado 2020

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

por Bartuzi, Paulina, Billadeau, Daniel D., Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H., Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K., Elliott, Alison M., Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D., Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart
Publicado 2016

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

por van Zwol, Willemien, Rimbert, Antoine, Wolters, Justina C., Smit, Marieke, Bloks, Vincent W., Kloosterhuis, Niels J., Huijkman, Nicolette C. A., Koster, Mirjam H., Tharehalli, Umesh, de Neck, Simon M., Bournez, Colin, Fuh, Marceline M., Kuipers, Jeroen, Rajan, Sujith, de Bruin, Alain, Ginsberg, Henry N., van Westen, Gerard J. P., Hussain, M. Mahmood, Scheja, Ludger, Heeren, Joerg, Zimmerman, Philip, van de Sluis, Bart, Kuivenhoven, Jan Albert
Publicado 2023

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death

por Seijkens, Tom T P, Poels, Kikkie, Meiler, Svenja, van Tiel, Claudia M, Kusters, Pascal J H, Reiche, Myrthe, Atzler, Dorothee, Winkels, Holger, Tjwa, Marc, Poelman, Hessel, Slütter, Bram, Kuiper, Johan, Gijbels, Marion, Kuivenhoven, Jan Albert, Matic, Ljubica Perisic, Paulsson-Berne, Gabrielle, Hedin, Ulf, Hansson, Göran K, Nicolaes, Gerry A F, Daemen, Mat J A P, Weber, Christian, Gerdes, Norbert, de Winther, Menno P J, Lutgens, Esther
Publicado 2019