The Role of Mitochondrial DNA Mutations in Mammalian Aging

por Kujoth, Gregory C, Bradshaw, Patrick C, Haroon, Suraiya, Prolla, Tomas A
Publicado 2007

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

por Uluç, Kutluay, Miranpuri, Amrendra, Kujoth, Gregory C., Aktüre, Erinç, Başkaya, Mustafa K.
Publicado 2011

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer’s disease

por Kukreja, Lokesh, Kujoth, Gregory C, Prolla, Tomas A, Van Leuven, Fred, Vassar, Robert
Publicado 2014

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice

por Someya, Shinichi, Kujoth, Gregory C., Kim, Mi-Jung, Hacker, Timothy A., Vermulst, Marc, Weindruch, Richard, Prolla, Tomas A.
Publicado 2017

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

por Kujoth, Gregory C., Sullivan, Thomas D., Merkhofer, Richard, Lee, Taek-Jin, Wang, Huafeng, Brandhorst, Tristan, Wüthrich, Marcel, Klein, Bruce S.
Publicado 2018

Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features

por Geurts, Jeroen, Nasi, Sonia, Distel, Pascal, Müller-Gerbl, Magdalena, Prolla, Tomas A., Kujoth, Gregory C., Walker, Ulrich A., Hügle, Thomas
Publicado 2020

Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions

por Fuke, Satoshi, Kametani, Mizue, Yamada, Kazuyuki, Kasahara, Takaoki, Kubota-Sakashita, Mie, Kujoth, Gregory C, Prolla, Tomas A, Hitoshi, Seiji, Kato, Tadafumi
Publicado 2014

Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging

por Joseph, Anna-Maria, Adhihetty, Peter J., Wawrzyniak, Nicholas R., Wohlgemuth, Stephanie E., Picca, Anna, Kujoth, Gregory C., Prolla, Tomas A., Leeuwenburgh, Christiaan
Publicado 2013

Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition

por Kuroki, Ryota, Murata, Yui, Fuke, Satoshi, Nakachi, Yutaka, Nakashima, Jun, Kujoth, Gregory C., Prolla, Tomas A., Bundo, Miki, Kato, Tadafumi, Iwamoto, Kazuya
Publicado 2020

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

por Dobson, Hannah E., Dias, Lucas Dos Santos, Kohn, Elaine M., Fites, Scott, Wiesner, Darin L., Dileepan, Thamotharampillai, Kujoth, Gregory C., Abraham, Ambily, Ostroff, Gary R., Klein, Bruce S., Wüthrich, Marcel
Publicado 2020

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

por Hiona, Asimina, Sanz, Alberto, Kujoth, Gregory C., Pamplona, Reinald, Seo, Arnold Y., Hofer, Tim, Someya, Shinichi, Miyakawa, Takuya, Nakayama, Chie, Samhan-Arias, Alejandro K., Servais, Stephane, Barger, Jamie L., Portero-Otín, Manuel, Tanokura, Masaru, Prolla, Tomas A., Leeuwenburgh, Christiaan
Publicado 2010

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity

por dos Santos Dias, Lucas, Dobson, Hannah E., Bakke, Brock Kingstad, Kujoth, Gregory C., Huang, Junfeng, Kohn, Elaine M., Taira, Cleison Ledesma, Wang, Huafeng, Supekar, Nitin T., Fites, J. Scott, Gates, Daisy, Gomez, Christina L., Specht, Charles A., Levitz, Stuart M., Azadi, Parastoo, Li, Lingjun, Suresh, Marulasiddappa, Klein, Bruce S., Wüthrich, Marcel
Publicado 2021