Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors

por Paramonov, Alexander S., Kocharovskaya, Milita V., Tsarev, Andrey V., Kulbatskii, Dmitrii S., Loktyushov, Eugene V., Shulepko, Mikhail A., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N., Shenkarev, Zakhar O.
Publicado 2020

Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells

por Lyukmanova, Ekaterina N., Zaigraev, Maxim M., Kulbatskii, Dmitrii S., Isaev, Aizek B., Kukushkin, Ilya D., Bychkov, Maxim L., Shulepko, Mikhail A., Chugunov, Anton O., Kirpichnikov, Mikhail P.
Publicado 2023

Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer

por Sudarikova, Anastasia V., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Chubinskiy-Nadezhdin, Vladislav I., Shlepova, Olga V., Shulepko, Mikhail A., Koshelev, Sergey G., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Publicado 2022

Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Phα1β Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer

por Lyukmanova, Ekaterina N., Mironov, Pavel A., Kulbatskii, Dmitrii S., Shulepko, Mikhail A., Paramonov, Alexander S., Chernaya, Elizaveta M., Logashina, Yulia A., Andreev, Yaroslav A., Kirpichnikov, Mikhail P., Shenkarev, Zakhar O.
Publicado 2023

New Three-Finger Protein from Starfish Asteria rubens Shares Structure and Pharmacology with Human Brain Neuromodulator Lynx2

por Paramonov, Alexander S., Shulepko, Mikhail A., Makhonin, Alexey M., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Chernikov, Andrey M., Myshkin, Mikhail Yu., Shabelnikov, Sergey V., Shenkarev, Zakhar O., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Publicado 2022

SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer

por Bychkov, Maxim L., Shulepko, Mikhail A., Shlepova, Olga V., Kulbatskii, Dmitrii S., Chulina, Irina A., Paramonov, Alexander S., Baidakova, Ludmila K., Azev, Viatcheslav N., Koshelev, Sergey G., Kirpichnikov, Mikhail P., Shenkarev, Zakhar O., Lyukmanova, Ekaterina N.
Publicado 2021

Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain

por Kulbatskii, Dmitrii, Shenkarev, Zakhar, Bychkov, Maxim, Loktyushov, Eugene, Shulepko, Mikhail, Koshelev, Sergey, Povarov, Igor, Popov, Alexander, Peigneur, Steve, Chugunov, Anton, Kozlov, Sergey, Sharonova, Irina, Efremov, Roman, Skrebitsky, Vladimir, Tytgat, Jan, Kirpichnikov, Mikhail, Lyukmanova, Ekaterina
Publicado 2021

Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor

por Lyukmanova, Ekaterina N., Shulepko, Mikhail A., Kudryavtsev, Denis, Bychkov, Maxim L., Kulbatskii, Dmitrii S., Kasheverov, Igor E., Astapova, Maria V., Feofanov, Alexey V., Thomsen, Morten S., Mikkelsen, Jens D., Shenkarev, Zakhar O., Tsetlin, Victor I., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P.
Publicado 2016

Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors

por Shenkarev, Zakhar O., Chesnokov, Yuri M., Zaigraev, Maxim M., Chugunov, Anton O., Kulbatskii, Dmitrii S., Kocharovskaya, Milita V., Paramonov, Alexander S., Bychkov, Maxim L., Shulepko, Mikhail A., Nolde, Dmitry E., Kamyshinsky, Roman A., Yablokov, Evgeniy O., Ivanov, Alexey S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Publicado 2022

Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na(v)1.4 Channel

por Myshkin, Mikhail Yu., Männikkö, Roope, Krumkacheva, Olesya A., Kulbatskii, Dmitrii S., Chugunov, Anton O., Berkut, Antonina A., Paramonov, Alexander S., Shulepko, Mikhail A., Fedin, Matvey V., Hanna, Michael G., Kullmann, Dimitri M., Bagryanskaya, Elena G., Arseniev, Alexander S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N., Vassilevski, Alexander A., Shenkarev, Zakhar O.
Publicado 2019

Spider toxin inhibits gating pore currents underlying periodic paralysis

por Männikkö, Roope, Shenkarev, Zakhar O., Thor, Michael G., Berkut, Antonina A., Myshkin, Mikhail Yu, Paramonov, Alexander S., Kulbatskii, Dmitrii S., Kuzmin, Dmitry A., Sampedro Castañeda, Marisol, King, Louise, Wilson, Emma R., Lyukmanova, Ekaterina N., Kirpichnikov, Mikhail P., Schorge, Stephanie, Bosmans, Frank, Hanna, Michael G., Kullmann, Dimitri M., Vassilevski, Alexander A.
Publicado 2018