Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

por Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Publicado 2020

Chronic Intranasal Treatment with an Anti-Aβ(30-42) scFv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

por Cattepoel, Susann, Hanenberg, Michael, Kulic, Luka, Nitsch, Roger M.
Publicado 2011

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

por Keskitalo, Salla, Farkas, Melinda, Hanenberg, Michael, Szodorai, Anita, Kulic, Luka, Semmler, Alexander, Weller, Michael, Nitsch, Roger M., Linnebank, Michael
Publicado 2014

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

por Kirabali, Tunahan, Rigotti, Serena, Siccoli, Alessandro, Liebsch, Filip, Shobo, Adeola, Hock, Christoph, Nitsch, Roger M., Multhaup, Gerhard, Kulic, Luka
Publicado 2019

Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer’s disease lacking functional B and T cells

por Späni, Claudia, Suter, Tobias, Derungs, Rebecca, Ferretti, Maria Teresa, Welt, Tobias, Wirth, Fabian, Gericke, Christoph, Nitsch, Roger M., Kulic, Luka
Publicado 2015

SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy

por Ni, Ruiqing, Zarb, Yvette, Kuhn, Gisela A., Müller, Ralph, Yundung, Yankey, Nitsch, Roger M., Kulic, Luka, Keller, Annika, Klohs, Jan
Publicado 2020

Evidence for Effects of Extracellular Vesicles on Physical, Inflammatory, Transcriptome and Reward Behaviour Status in Mice

por Cuomo-Haymour, Nagiua, Sigrist, Hannes, Ineichen, Christian, Russo, Giancarlo, Nüesch, Ursina, Gantenbein, Felix, Kulic, Luka, Knuesel, Irene, Bergamini, Giorgio, Pryce, Christopher Robert
Publicado 2022

Differential Expression of Serum Extracellular Vesicle miRNAs in Multiple Sclerosis: Disease-Stage Specificity and Relevance to Pathophysiology

por Cuomo-Haymour, Nagiua, Bergamini, Giorgio, Russo, Giancarlo, Kulic, Luka, Knuesel, Irene, Martin, Roland, Huss, André, Tumani, Hayrettin, Otto, Markus, Pryce, Christopher R.
Publicado 2022

fMRI Reveals Mitigation of Cerebrovascular Dysfunction by Bradykinin Receptors 1 and 2 Inhibitor Noscapine in a Mouse Model of Cerebral Amyloidosis

por Ni, Ruiqing, Kindler, Diana Rita, Waag, Rebecca, Rouault, Marie, Ravikumar, Priyanka, Nitsch, Roger, Rudin, Markus, Camici, Giovanni G., Liberale, Luca, Kulic, Luka, Klohs, Jan
Publicado 2019

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis

por Ulku, Irem, Liebsch, Filip, Akerman, S. Can, Schulz, Jana F., Kulic, Luka, Hock, Christoph, Pietrzik, Claus, Di Spiezio, Alessandro, Thinakaran, Gopal, Saftig, Paul, Multhaup, Gerhard
Publicado 2023

A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

por Rust, Ruslan, Kirabali, Tunahan, Grönnert, Lisa, Dogancay, Berre, Limasale, Yanuar D. P., Meinhardt, Andrea, Werner, Carsten, Laviña, Bàrbara, Kulic, Luka, Nitsch, Roger M., Tackenberg, Christian, Schwab, Martin E.
Publicado 2020

RETRACTED ARTICLE: Age-dependent Increase in Desmosterol Restores DRM Formation and Membrane-related Functions in Cholesterol-free DHCR24(−/−) Mice

por Kuehnle, Katrin, Ledesma, Maria D., Kalvodova, Lucie, Smith, Alicia E., Crameri, Arames, Skaanes-Brunner, Fabienne, Thelen, Karin M., Kulic, Luka, Lütjohann, Dieter, Heppner, Frank L., Nitsch, Roger M., Mohajeri, M. Hasan
Publicado 2008

Age-dependent Increase in Desmosterol Restores DRM Formation and Membrane-related Functions in Cholesterol-free DHCR24(−/−) Mice

por Kuehnle, Katrin, Ledesma, Maria D., Kalvodova, Lucie, Smith, Alicia E., Crameri, Arames, Skaanes-Brunner, Fabienne, Thelen, Karin M., Kulic, Luka, Lütjohann, Dieter, Heppner, Frank L., Nitsch, Roger M., Mohajeri, M. Hasan
Publicado 2009

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

por Liebsch, Filip, Kulic, Luka, Teunissen, Charlotte, Shobo, Adeola, Ulku, Irem, Engelschalt, Vivienne, Hancock, Mark A., van der Flier, Wiesje M., Kunach, Peter, Rosa-Neto, Pedro, Scheltens, Philip, Poirier, Judes, Saftig, Paul, Bateman, Randall J., Breitner, John, Hock, Christoph, Multhaup, Gerhard
Publicado 2019

Multicenter Analytical Validation of Aβ40 Immunoassays

por van Waalwijk van Doorn, Linda J. C., Kulic, Luka, Koel-Simmelink, Marleen J. A., Kuiperij, H. Bea, Versleijen, Alexandra A. M., Struyfs, Hanne, Twaalfhoven, Harry A. M., Fourier, Anthony, Engelborghs, Sebastiaan, Perret-Liaudet, Armand, Lehmann, Sylvain, Verbeek, Marcel M., Vanmechelen, Eugeen J. M., Teunissen, Charlotte E.
Publicado 2017

A Practical Guide to Immunoassay Method Validation

por Andreasson, Ulf, Perret-Liaudet, Armand, van Waalwijk van Doorn, Linda J. C., Blennow, Kaj, Chiasserini, Davide, Engelborghs, Sebastiaan, Fladby, Tormod, Genc, Sermin, Kruse, Niels, Kuiperij, H. Bea, Kulic, Luka, Lewczuk, Piotr, Mollenhauer, Brit, Mroczko, Barbara, Parnetti, Lucilla, Vanmechelen, Eugeen, Verbeek, Marcel M., Winblad, Bengt, Zetterberg, Henrik, Koel-Simmelink, Marleen, Teunissen, Charlotte E.
Publicado 2015

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

por Reijs, Babette L. R., Teunissen, Charlotte E., Goncharenko, Nikolai, Betsou, Fay, Blennow, Kaj, Baldeiras, Inês, Brosseron, Frederic, Cavedo, Enrica, Fladby, Tormod, Froelich, Lutz, Gabryelewicz, Tomasz, Gurvit, Hakan, Kapaki, Elisabeth, Koson, Peter, Kulic, Luka, Lehmann, Sylvain, Lewczuk, Piotr, Lleó, Alberto, Maetzler, Walter, de Mendonça, Alexandre, Miller, Anne-Marie, Molinuevo, José L., Mollenhauer, Brit, Parnetti, Lucilla, Rot, Uros, Schneider, Anja, Simonsen, Anja Hviid, Tagliavini, Fabrizio, Tsolaki, Magda, Verbeek, Marcel M., Verhey, Frans R. J., Zboch, Marzena, Winblad, Bengt, Scheltens, Philip, Zetterberg, Henrik, Visser, Pieter Jelle
Publicado 2015