The Role of AKT/mTOR Pathway in Stress Response to UV-Irradiation: Implication in Skin Carcinogenesis by Regulation of Apoptosis, Autophagy and Senescence

por Strozyk, Elwira, Kulms, Dagmar
Publicado 2013

A 3D Organotypic Melanoma Spheroid Skin Model

por Müller, Ines, Kulms, Dagmar
Publicado 2018

Cell death and regeneration in Dresden—the 27th meeting of the European Cell Death Organization

por Linkermann, Andreas, Kulms, Dagmar
Publicado 2019

Anti-Apoptotic NF-κB and “Gain of Function” mutp53 in Concert Act Pro-Apoptotic in Response to UVB+IL-1 via Enhanced TNF Production

por Müller, Ines, Beissert, Stefan, Kulms, Dagmar
Publicado 2015

Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach

por Konrath, Fabian, Witt, Johannes, Sauter, Thomas, Kulms, Dagmar
Publicado 2014

Computational models of melanoma

por Albrecht, Marco, Lucarelli, Philippe, Kulms, Dagmar, Sauter, Thomas
Publicado 2020

Mechanistically Coupled PK (MCPK) Model to Describe Enzyme Induction and Occupancy Dependent DDI of Dabrafenib Metabolism

por Albrecht, Marco, Kogan, Yuri, Kulms, Dagmar, Sauter, Thomas
Publicado 2022

Modeling time delay in the NFκB signaling pathway following low dose IL-1 stimulation

por Witt, Johannes, Barisic, Sandra, Sawodny, Oliver, Ederer, Michael, Kulms, Dagmar, Sauter, Thomas
Publicado 2011

Analysing the Role of UVB-Induced Translational Inhibition and PP2Ac Deactivation in NF-κB Signalling Using a Minimal Mathematical Model

por Witt, Johannes, Konrath, Fabian, Sawodny, Oliver, Ederer, Michael, Kulms, Dagmar, Sauter, Thomas
Publicado 2012

Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach

por Witt, Johannes, Barisic, Sandra, Schumann, Eva, Allgöwer, Frank, Sawodny, Oliver, Sauter, Thomas, Kulms, Dagmar
Publicado 2009

Ultraviolet Light Induces Apoptosis via Direct Activation of CD95 (Fas/APO-1) Independently of Its Ligand CD95L

por Aragane, Yoshinori, Kulms, Dagmar, Metze, Dieter, Wilkes, Gabriele, Pöppelmann, Birgit, Luger, Thomas A., Schwarz, Thomas
Publicado 1998

Identifying and targeting cancer-specific metabolism with network-based drug target prediction

por Pacheco, Maria Pires, Bintener, Tamara, Ternes, Dominik, Kulms, Dagmar, Haan, Serge, Letellier, Elisabeth, Sauter, Thomas
Publicado 2019

IgG-single-chain TRAIL fusion proteins for tumour therapy

por Siegemund, Martin, Schneider, Felix, Hutt, Meike, Seifert, Oliver, Müller, Ines, Kulms, Dagmar, Pfizenmaier, Klaus, Kontermann, Roland E.
Publicado 2018

Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells

por Margue, Christiane, Philippidou, Demetra, Kozar, Ines, Cesi, Giulia, Felten, Paul, Kulms, Dagmar, Letellier, Elisabeth, Haan, Claude, Kreis, Stephanie
Publicado 2019

The TAT-RasGAP(317-326) anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner

por Heulot, Mathieu, Chevalier, Nadja, Puyal, Julien, Margue, Christiane, Michel, Sébastien, Kreis, Stephanie, Kulms, Dagmar, Barras, David, Nahimana, Aimable, Widmann, Christian
Publicado 2016

Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism

por Vetma, Vesna, Guttà, Cristiano, Peters, Nathalie, Praetorius, Christian, Hutt, Meike, Seifert, Oliver, Meier, Friedegund, Kontermann, Roland, Kulms, Dagmar, Rehm, Markus
Publicado 2020

Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma

por Del Mistro, Greta, Riemann, Shamala, Schindler, Sebastian, Beissert, Stefan, Kontermann, Roland E., Ginolhac, Aurelien, Halder, Rashi, Presta, Luana, Sinkkonen, Lasse, Sauter, Thomas, Kulms, Dagmar
Publicado 2022

Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma

por Del Mistro, Greta, Lucarelli, Philippe, Müller, Ines, De Landtsheer, Sébastien, Zinoveva, Anna, Hutt, Meike, Siegemund, Martin, Kontermann, Roland E., Beissert, Stefan, Sauter, Thomas, Kulms, Dagmar
Publicado 2018

Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids

por Phan, Truong San, Schink, Leonhard, Mann, Jasmin, Merk, Verena M., Zwicky, Pascale, Mundt, Sarah, Simon, Dagmar, Kulms, Dagmar, Abraham, Susanne, Legler, Daniel F., Noti, Mario, Brunner, Thomas
Publicado 2021

XIAP promotes melanoma growth by inducing tumour neutrophil infiltration

por Daoud, Mila, Broxtermann, Pia Nora, Schorn, Fabian, Werthenbach, J Paul, Seeger, Jens Michael, Schiffmann, Lars M, Brinkmann, Kerstin, Vucic, Domagoj, Tüting, Thomas, Mauch, Cornelia, Kulms, Dagmar, Zigrino, Paola, Kashkar, Hamid
Publicado 2022