Generalized Fragment Picking in Rosetta: Design, Protocols and Applications

por Gront, Dominik, Kulp, Daniel W., Vernon, Robert M., Strauss, Charlie E. M., Baker, David
Publicado 2011

Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations

por Xu, Ziyang, Chokkalingam, Neethu, Tello-Ruiz, Edgar, Walker, Susanne, Kulp, Daniel W., Weiner, David B.
Publicado 2020

Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases

por Xu, Ziyang, Patel, Ami, Tursi, Nicholas J., Zhu, Xizhou, Muthumani, Kar, Kulp, Daniel W., Weiner, David B.
Publicado 2020

A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy

por Bordoloi, Devivasha, Bhojnagarwala, Pratik S., Perales-Puchalt, Alfredo, Kulkarni, Abhijeet J., Zhu, Xizhou, Liaw, Kevin, O’Connell, Ryan P., Park, Daniel H., Kulp, Daniel W., Zhang, Rugang, Weiner, David B.
Publicado 2022

Altering the O(2)-Dependent Reactivity of de novo Due Ferri Proteins

por Reig, Amanda J., Pires, Marcos M., Snyder, Rae Ana, Wu, Yibing, Jo, Hyunil, Kulp, Daniel W., Butch, Susan E., Calhoun, Jennifer R., Szyperski, Thomas, Solomon, Edward I., DeGrado, William F.
Publicado 2012

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

por Tokatlian, Talar, Kulp, Daniel W., Mutafyan, Andrew A., Jones, Christopher A., Menis, Sergey, Georgeson, Erik, Kubitz, Mike, Zhang, Michael H., Melo, Mariane B., Silva, Murillo, Yun, Dong Soo, Schief, William R., Irvine, Darrell J.
Publicado 2018

Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

por Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce, Parzych, Elizabeth M., Ali, Ali R., Frase, Drew, Moffat, Estella, Embury-Hyatt, Carissa, Smith, Trevor R.F., Broderick, Kate E., Humeau, Laurent, Kobasa, Darwyn, Patel, Ami, Kulp, Daniel W., Weiner, David B.
Publicado 2022

Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo

por Tursi, Nicholas J., Xu, Ziyang, Helble, Michaela, Walker, Susanne, Liaw, Kevin, Chokkalingam, Neethu, Kannan, Toshitha, Wu, Yuanhan, Tello-Ruiz, Edgar, Park, Daniel H., Zhu, Xizhou, Wise, Megan C., Smith, Trevor R. F., Majumdar, Sonali, Kossenkov, Andrew, Kulp, Daniel W., Weiner, David B.
Publicado 2023

SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients

por Walker, Susanne N., Chokkalingam, Neethu, Reuschel, Emma L., Purwar, Mansi, Xu, Ziyang, Gary, Ebony N., Kim, Kevin Y., Helble, Michaela, Schultheis, Katherine, Walters, Jewell, Ramos, Stephanie, Muthumani, Kar, Smith, Trevor R. F., Broderick, Kate E., Tebas, Pablo, Patel, Ami, Weiner, David B., Kulp, Daniel W.
Publicado 2020

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

por Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Publicado 2017

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado 2017

Nanoparticle Vaccines: In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity (Adv...

por Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Publicado 2020

In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity

por Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Publicado 2020

Engineered immunogen binding to alum adjuvant enhances humoral immunity

por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado 2020

Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado 2020

Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer

por Xu, Ziyang, Walker, Susanne, Wise, Megan C., Chokkalingam, Neethu, Purwar, Mansi, Moore, Alan, Tello-Ruiz, Edgar, Wu, Yuanhan, Majumdar, Sonali, Konrath, Kylie M., Kulkarni, Abhijeet, Tursi, Nicholas J., Zaidi, Faraz I., Reuschel, Emma L., Patel, Ishaan, Obeirne, April, Du, Jianqiu, Schultheis, Katherine, Gites, Lauren, Smith, Trevor, Mendoza, Janess, Broderick, Kate E., Humeau, Laurent, Pallesen, Jesper, Weiner, David B., Kulp, Daniel W.
Publicado 2022

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado 2016

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

por Steichen, Jon M., Kulp, Daniel W., Tokatlian, Talar, Escolano, Amelia, Dosenovic, Pia, Stanfield, Robyn L., McCoy, Laura E., Ozorowski, Gabriel, Hu, Xiaozhen, Kalyuzhniy, Oleksandr, Briney, Bryan, Schiffner, Torben, Garces, Fernando, Freund, Natalia T., Gitlin, Alexander D., Menis, Sergey, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Jones, Meaghan, Mutafyan, Andrew A., Yun, Dong Soo, Mayer, Christian T., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A., Irvine, Darrell J., Nussenzweig, Michel C., Schief, William R.
Publicado 2016

Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection

por Konrath, Kylie M., Liaw, Kevin, Wu, Yuanhan, Zhu, Xizhou, Walker, Susanne N., Xu, Ziyang, Schultheis, Katherine, Chokkalingam, Neethu, Chawla, Himanshi, Du, Jianqiu, Tursi, Nicholas J., Moore, Alan, Adolf-Bryfogle, Jared, Purwar, Mansi, Reuschel, Emma L., Frase, Drew, Sullivan, Matthew, Fry, Benjamin, Maricic, Igor, Andrade, Viviane M., Iffland, Christel, Crispin, Max, Broderick, Kate E., Humeau, Laurent M.P.F., Patel, Ami, Smith, Trevor R.F., Pallesen, Jesper, Weiner, David B., Kulp, Daniel W.
Publicado 2022

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

por Pauthner, Matthias G., Nkolola, Joseph P., Havenar-Daughton, Colin, Murrell, Ben, Reiss, Samantha M., Bastidas, Raiza, Prévost, Jérémie, Nedellec, Rebecca, von Bredow, Benjamin, Abbink, Peter, Cottrell, Christopher A., Kulp, Daniel W., Tokatlian, Talar, Nogal, Bartek, Bianchi, Matteo, Li, Hui, Lee, Jeong Hyun, Butera, Salvatore T., Evans, David T., Hangartner, Lars, Finzi, Andrés, Wilson, Ian A., Wyatt, Richard T., Irvine, Darrell J., Schief, William R., Ward, Andrew B., Sanders, Rogier W., Crotty, Shane, Shaw, George M., Barouch, Dan H., Burton, Dennis R.
Publicado 2019