Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Isavuconazonium Sulfate in Healthy Adult Japanese Subjects

por Shirae, Shinichiro, Ose, Atsushi, Kumagai, Yuji
Publicado 2022

Safety Profiles, Pharmacokinetics, and Changes in Bone Turnover Markers After Twice‐Weekly Subcutaneous Administration of Teriparatide in Healthy Japanese Postmenopausal Women: A S...

por Kumagai, Yuji, Ose, Atsushi, Tanaka, Kosuke, Sugimoto, Toshitsugu
Publicado 2019

A drug–drug interaction study of a novel, selective urate reabsorption inhibitor dotinurad and the non-steroidal anti-inflammatory drug oxaprozin in healthy adult males

por Furihata, Kenichi, Nagasawa, Katsuaki, Hagino, Atsushi, Kumagai, Yuji
Publicado 2020

Population pharmacokinetics of phenytoin after intravenous administration of fosphenytoin sodium in pediatric patients, adult patients, and healthy volunteers

por Tanaka, Jun, Kasai, Hidefumi, Shimizu, Kenji, Shimasaki, Shigeki, Kumagai, Yuji
Publicado 2012

Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects

por Kumagai, Yuji, Hasunuma, Tomoko, Sakai, Soichi, Ochiai, Hidekazu, Samukawa, Yoshishige
Publicado 2015

Comparison of circulating lipid profiles between fasting humans and three animal species used in preclinical studies: mice, rats and rabbits

por Ishikawa, Masaki, Saito, Kosuke, Urata, Masayo, Kumagai, Yuji, Maekawa, Keiko, Saito, Yoshiro
Publicado 2015

Strategy to avoid local recurrence in patients with locally advanced rectal cancer

por Nakamura, Takatoshi, Sato, Takeo, Hayakawa, Kazushige, Koizumi, Wasaburou, Kumagai, Yuji, Watanabe, Masahiko
Publicado 2019

Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial

por Kumagai, Yuji, Amano, Hideki, Sasaki, Yoshinobu, Nakagawa, Chie, Maeda, Mika, Oikawa, Ichiro, Furuie, Hidetoshi
Publicado 2018

Mammaglobin 1 mediates progression of trastuzumab‐resistant breast cancer cells through regulation of cyclins and NF‐κB

por Kusumastuti, Ratih, Kumagai, Yuji, Ishihara, Seiichiro, Enomoto, Atsushi, Murakami, Takashi, Yasuda, Motoaki, Haga, Hisashi
Publicado 2022

The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces

por Kumagai, Yuji, Nio-Kobayashi, Junko, Ishihara, Seiichiro, Enomoto, Atsushi, Akiyama, Masashi, Ichihara, Ryosuke, Haga, Hisashi
Publicado 2022

A Drug‐Drug Interaction Study to Evaluate the Effect of TAS‐303 on CYP3A Activity in the Small Intestine and Liver

por Kumagai, Yuji, Fujita, Tomoe, Maeda, Mika, Sasaki, Yoshinobu, Nagaoka, Makoto, Huang, Jinhong, Takenaka, Toru, Kawai, Masaki
Publicado 2020

Plasma and Serum Lipidomics of Healthy White Adults Shows Characteristic Profiles by Subjects’ Gender and Age

por Ishikawa, Masaki, Maekawa, Keiko, Saito, Kosuke, Senoo, Yuya, Urata, Masayo, Murayama, Mayumi, Tajima, Yoko, Kumagai, Yuji, Saito, Yoshiro
Publicado 2014

Effects of Sex, Age, and Fasting Conditions on Plasma Lipidomic Profiles of Fasted Sprague-Dawley Rats

por Saito, Kosuke, Ishikawa, Masaki, Murayama, Mayumi, Urata, Masayo, Senoo, Yuya, Toyoshima, Katsuko, Kumagai, Yuji, Maekawa, Keiko, Saito, Yoshiro
Publicado 2014

Dotinurad: a clinical pharmacokinetic study of a novel, selective urate reabsorption inhibitor in subjects with hepatic impairment

por Kumagai, Yuji, Sakaki, Masashi, Furihata, Kenichi, Ito, Takayoshi, Inoue, Kazuaki, Yoshida, Takafumi, Matsumoto, Shigeki, Furuno, Kazuki, Hagino, Atsushi
Publicado 2019

Real‐world evidence of population differences in allopurinol‐related severe cutaneous adverse reactions in East Asians: A population‐based cohort study

por Sato, Tsugumichi, Cheng, Ching‐Lan, Park, Heung‐Woo, Kao Yang, Yea‐Huei, Yang, Min‐Suk, Fujita, Mizuki, Kumagai, Yuji, Tohkin, Masahiro, Saito, Yoshiro, Sai, Kimie
Publicado 2021

The necessary conduct: Exploratory multiregional clinical trials in East Asia

por Jeon, Inseung, Kim, Yu Kyong, Song, Ildae, Yoon, Deok Yong, Huh, Ki Young, Jin, Xuanyou, Yu, Kyung‐Sang, Lee, SeungHwan, Kumagai, Yuji, Jang, In‐Jin
Publicado 2021

A Double-Blind, Randomized, Crossover Comparative Study for Evaluating the Clinical Safety of Ephedrine Alkaloids-Free Ephedra Herb Extract (EFE)

por Odaguchi, Hiroshi, Sekine, Mariko, Hyuga, Sumiko, Hanawa, Toshihiko, Hoshi, Keika, Sasaki, Yoshinobu, Aso, Masako, Yang, Jinwei, Hyuga, Masashi, Kobayashi, Yoshinori, Hakamatsuka, Takashi, Goda, Yukihiro, Kumagai, Yuji
Publicado 2018

Effects of Low-Dose Colchicine on Serum High-Sensitivity C-Reactive Protein Level in Coronary Artery Disease Patients with Type 2 Diabetes Mellitus and Enhanced Inflammatory Respon...

por Miwa, Yoshikazu, Mutoh, Akiko, Morimoto, Takeshi, Ikehara, Yumi, Yasu, Takanori, Koba, Shinji, Ako, Junya, Higashi, Yukihito, Kajikawa, Masato, Uehara, Hiroki, Ishikawa, Kazuo, Sakuma, Ichiro, Tomiyama, Hirofumi, Node, Koichi, Kumagai, Yuji, Ueda, Shinichiro
Publicado 2022

Plasma Lipid Profiling of Three Types of Drug-Induced Liver Injury in Japanese Patients: A Preliminary Study

por Saito, Kosuke, Kagawa, Tatehiro, Tsuji, Keiji, Kumagai, Yuji, Sato, Ken, Sakisaka, Shotaro, Sakamoto, Naoya, Aiso, Mitsuhiko, Hirose, Shunji, Mori, Nami, Tanaka, Rieko, Uraoka, Toshio, Takata, Kazuhide, Ogawa, Koji, Mori, Kazuhiko, Sato, Motonobu, Nishiya, Takayoshi, Takamatsu, Kazuhiko, Arakawa, Noriaki, Izumi, Takashi, Ohno, Yasuo, Saito, Yoshiro, Takikawa, Hajime
Publicado 2020

Efficacy and safety of single-dose ivermectin in mild-to-moderate COVID-19: the double-blind, randomized, placebo-controlled CORVETTE-01 trial

por Wada, Tatsuhiko, Hibino, Makoto, Aono, Hiromi, Kyoda, Shunsuke, Iwadate, Yosuke, Shishido, Eri, Ikeda, Keisuke, Kinoshita, Nana, Matsuda, Yasuki, Otani, Sakiko, Kameda, Ryo, Matoba, Kenta, Nonaka, Miwa, Maeda, Mika, Kumagai, Yuji, Ako, Junya, Shichiri, Masayoshi, Naoki, Katsuhiko, Katagiri, Masato, Takaso, Masashi, Iwamura, Masatsugu, Katayama, Kazuhiko, Miyatsuka, Takeshi, Orihashi, Yasushi, Yamaoka, Kunihiro
Publicado 2023