Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs

por Graziano, Giovanni, Stefanachi, Angela, Contino, Marialessandra, Prieto-Díaz, Rubén, Ligresti, Alessia, Kumar, Poulami, Scilimati, Antonio, Sotelo, Eddy, Leonetti, Francesco
Publicado 2023

N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Rece...

por Gianquinto, Eleonora, Sodano, Federica, Rolando, Barbara, Kostrzewa, Magdalena, Allarà, Marco, Mahmoud, Ali Mokhtar, Kumar, Poulami, Spyrakis, Francesca, Ligresti, Alessia, Chegaev, Konstantin
Publicado 2022

Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists

por Cho, Analia Young Hwa, Chung, Hery, Romero-Parra, Javier, Kumar, Poulami, Allarà, Marco, Ligresti, Alessia, Gallardo-Garrido, Carlos, Pessoa-Mahana, Hernán, Faúndez, Mario, Pessoa-Mahana, Carlos David
Publicado 2023

Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and...

por Mugnaini, Claudia, Kostrzewa, Magdalena, Casini, Marta, Kumar, Poulami, Catallo, Valeria, Allarà, Marco, Guastaferro, Laura, Brizzi, Antonella, Paolino, Marco, Tafi, Andrea, Kapatais, Christelos, Giorgi, Gianluca, Vacondio, Federica, Mor, Marco, Corelli, Federico, Ligresti, Alessia
Publicado 2023