Landscape of gene fusions in epithelial cancers: seq and ye shall find

por Kumar-Sinha, Chandan, Kalyana-Sundaram, Shanker, Chinnaiyan, Arul M.
Publicado 2015

RNA-Seq Accurately Identifies Cancer Biomarker Signatures to Distinguish Tissue of Origin()

por Wei, Iris H., Shi, Yang, Jiang, Hui, Kumar-Sinha, Chandan, Chinnaiyan, Arul M.
Publicado 2014

The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function

por Rai, Rekha, Gu, Peili, Broton, Cayla, Kumar-Sinha, Chandan, Chen, Yong, Chang, Sandy
Publicado 2019

Expression profiling of cervical cancers in Indian women at different stages to identify gene signatures during progression of the disease

por Thomas, Asha, Mahantshetty, Umesh, Kannan, Sadhana, Deodhar, Kedar, Shrivastava, Shyam K, Kumar-Sinha, Chandan, Mulherkar, Rita
Publicado 2013

Identification of Novel PGR-NR4A3 Fusion in Extraskeletal Myxoid Chondrosarcoma and Resultant Patient Benefit From Tamoxifen Therapy

por Wilbur, H. Catherine, Robinson, Dan R., Wu, Yi-Mi, Kumar-Sinha, Chandan, Chinnaiyan, Arul M., Chugh, Rashmi
Publicado 2022

Double-Negative Prostate Cancer Masquerading as a Squamous Cancer of Unknown Primary: A Clinicopathologic and Genomic Sequencing-Based Case Study

por Cackowski, Frank C., Kumar-Sinha, Chandan, Mehra, Rohit, Wu, Yi-Mi, Robinson, Dan R., Alumkal, Joshi J., Chinnaiyan, Arul M.
Publicado 2020

Molecular insights into malignant progression of atypical choroid plexus papilloma

por Yankelevich, Maxim, Finlay, Jonathan L., Gorsi, Hamza, Kupsky, William, Boue, Daniel R., Koschmann, Carl J., Kumar-Sinha, Chandan, Mody, Rajen
Publicado 2021

Pathogenic ATM and BAP1 germline mutations in a case of early-onset, familial sarcomatoid renal cancer

por Bell, Hannah N., Kumar-Sinha, Chandan, Mannan, Rahul, Zakalik, Dana, Zhang, Yuping, Mehra, Rohit, Jagtap, Deepa, Dhanasekaran, Saravana M., Vaishampayan, Ulka
Publicado 2022

SAT-549 Identification of Somatic Mutations in CLCN2 as a Cause of Aldosterone-Producing Adenomas

por Rege, Juilee, Nanba, Kazutaka, Blinder, Amy R, Else, Tobias, Tomlins, Scott, Vats, Pankaj, Kumar-Sinha, Chandan, Giordano, Thomas J, Rainey, William E
Publicado 2020

Transcriptome Sequencing to Detect Gene Fusions in Cancer

por Maher, Christopher A., Kumar-Sinha, Chandan, Cao, Xuhong, Kalyana-Sundaram, Shanker, Han, Bo, Jing, Xiaojun, Sam, Lee, Barrette, Terrence, Palanisamy, Nallasivam, Chinnaiyan, Arul M.
Publicado 2009

A Comparison of Single Molecule and Amplification Based Sequencing of Cancer Transcriptomes

por Sam, Lee T., Lipson, Doron, Raz, Tal, Cao, Xuhong, Thompson, John, Milos, Patrice M., Robinson, Dan, Chinnaiyan, Arul M., Kumar-Sinha, Chandan, Maher, Christopher A.
Publicado 2011

Identification of Somatic Mutations in CLCN2 in Aldosterone-Producing Adenomas

por Rege, Juilee, Nanba, Kazutaka, Blinder, Amy R, Plaska, Samuel, Udager, Aaron M, Vats, Pankaj, Kumar-Sinha, Chandan, Giordano, Thomas J, Rainey, William E, Else, Tobias
Publicado 2020

Ultra‐Specific Isolation of Circulating Tumor Cells Enables Rare‐Cell RNA Profiling

por Jack, Rhonda M., Grafton, Meggie M. G., Rodrigues, Danika, Giraldez, Maria D., Griffith, Catherine, Cieslak, Robert, Zeinali, Mina, Kumar Sinha, Chandan, Azizi, Ebrahim, Wicha, Max, Tewari, Muneesh, Simeone, Diane M., Nagrath, Sunitha
Publicado 2016

Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer

por Overman, Michael, Javle, Milind, Davis, Richard E, Vats, Pankaj, Kumar-Sinha, Chandan, Xiao, Lianchun, Mettu, Niharika B, Parra, Edwin R, Benson, Al B, Lopez, Charles D, Munugalavadla, Veerendra, Patel, Priti, Tao, Lin, Neelapu, Sattva, Maitra, Anirban
Publicado 2020

HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties

por Abel, Ethan V, Goto, Masashi, Magnuson, Brian, Abraham, Saji, Ramanathan, Nikita, Hotaling, Emily, Alaniz, Anthony A, Kumar-Sinha, Chandan, Dziubinski, Michele L, Urs, Sumithra, Wang, Lidong, Shi, Jiaqi, Waghray, Meghna, Ljungman, Mats, Crawford, Howard C, Simeone, Diane M
Publicado 2018

Genomics driven precision oncology in advanced biliary tract cancer improves survival

por Kumar-Sinha, Chandan, Vats, Pankaj, Tran, Nguyen, Robinson, Dan R., Gunchick, Valerie, Wu, Yi-Mi, Cao, Xuhong, Ning, Yu, Wang, Rui, Rabban, Erica, Bell, Janice, Shankar, Sunita, Mannan, Rahul, Zhang, Yuping, Zalupski, Mark M., Chinnaiyan, Arul M., Sahai, Vaibhav
Publicado 2023

Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer

por Chen, Cong, Gu, Peili, Wu, Jian, Chen, Xianyun, Niu, Shuangshuang, Sun, Hong, Wu, Lijie, Li, Na, Peng, Junhui, Shi, Shaohua, Fan, Cuiying, Huang, Min, Wong, Catherine C. L., Gong, Qingguo, Kumar-Sinha, Chandan, Zhang, Rongguang, Pusztai, Lajos, Rai, Rekha, Chang, Sandy, Lei, Ming
Publicado 2017

Optimizing Precision Medicine for Breast Cancer Brain Metastases with Functional Drug Response Assessment

por Morikawa, Aki, Li, Jinju, Ulintz, Peter, Cheng, Xu, Apfel, Athena, Robinson, Dan, Hopkins, Alex, Kumar-Sinha, Chandan, Wu, Yi-Mi, Serhan, Habib, Verbal, Kait, Thomas, Dafydd, Hayes, Daniel F., Chinnaiyan, Arul M., Baladandayuthapani, Veerabhadran, Heth, Jason, Soellner, Matthew B., Merajver, Sofia D., Merrill, Nathan
Publicado 2023

OR02-01 Somatic Mutations In The Zinc Transporter ZnT1 Cause Primary Aldosteronism

por Rege, Juilee, Bandulik, Sascha, Nanba, Kazutaka, Kosmann, Carla, Blinder, Amy, Plain, Allen, Vats, Pankaj, Kumar-Sinha, Chandan, Marcondes Lerario, Antonio, Else, Tobias, Yamazaki, Yuto, Satoh, Fumitoshi, Sasano, Hironobu, Giordano, Thomas J, Ann Williams, Tracy, Reincke, Martin, Turcu, Adina, Udager, Aaron, Warth, Richard, Rainey, William E
Publicado 2023

Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response

por Zhang, Yuping, Narayanan, Sathiya P., Mannan, Rahul, Raskind, Gregory, Wang, Xiaoming, Vats, Pankaj, Su, Fengyun, Hosseini, Noshad, Cao, Xuhong, Kumar-Sinha, Chandan, Ellison, Stephanie J., Giordano, Thomas J., Morgan, Todd M., Pitchiaya, Sethuramasundaram, Alva, Ajjai, Mehra, Rohit, Cieslik, Marcin, Dhanasekaran, Saravana M., Chinnaiyan, Arul M.
Publicado 2021