PDGFRα and CD51 mark human Nestin(+) sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

por Pinho, Sandra, Lacombe, Julie, Hanoun, Maher, Mizoguchi, Toshihide, Bruns, Ingmar, Kunisaki, Yuya, Frenette, Paul S.
Publicado 2013

GPAM mediated lysophosphatidic acid synthesis regulates mitochondrial dynamics in acute myeloid leukemia

por Irifune, Hidetoshi, Kochi, Yu, Miyamoto, Toshihiro, Sakoda, Teppei, Kato, Koji, Kunisaki, Yuya, Akashi, Koichi, Kikushige, Yoshikane
Publicado 2023

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

por Lucas, Daniel, Scheiermann, Christoph, Chow, Andrew, Kunisaki, Yuya, Bruns, Ingmar, Barrick, Colleen, Tessarollo, Lino, Frenette, Paul S.
Publicado 2013

TIM-3 signaling hijacks the canonical Wnt/β-catenin pathway to maintain cancer stemness in acute myeloid leukemia

por Sakoda, Teppei, Kikushige, Yoshikane, Miyamoto, Toshihiro, Irifune, Hidetoshi, Harada, Takuya, Hatakeyama, Kiwamu, Kunisaki, Yuya, Kato, Koji, Akashi, Koichi
Publicado 2023

Differential cytokine contributions of perivascular haematopoietic stem cell niches

por Asada, Noboru, Kunisaki, Yuya, Pierce, Halley, Wang, Zichen, Fernandez, Nicolas F., Birbrair, Alexander, Ma’ayan, Avi, Frenette, Paul S.
Publicado 2017

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

por Jiang, Hongsi, Pan, Fan, Erickson, Laurie M., Jang, Mei-Shiang, Sanui, Terukazu, Kunisaki, Yuya, Sasazuki, Takehiko, Kobayashi, Masakazu, Fukui, Yoshinori
Publicado 2005

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

por Kunisaki, Yuya, Nishikimi, Akihiko, Tanaka, Yoshihiko, Takii, Ryosuke, Noda, Mayuko, Inayoshi, Ayumi, Watanabe, Ken-ichi, Sanematsu, Fumiyuki, Sasazuki, Takehiko, Sasaki, Takehiko, Fukui, Yoshinori
Publicado 2006

Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion

por Bruns, Ingmar, Lucas, Daniel, Pinho, Sandra, Ahmed, Jalal, Lambert, Michele P., Kunisaki, Yuya, Scheiermann, Christoph, Schiff, Lauren, Poncz, Mortimer, Bergman, Aviv, Frenette, Paul S.
Publicado 2014

Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit(Wv) Mutations

por Yurino, Ayano, Takenaka, Katsuto, Yamauchi, Takuji, Nunomura, Takuya, Uehara, Yasufumi, Jinnouchi, Fumiaki, Miyawaki, Kohta, Kikushige, Yoshikane, Kato, Koji, Miyamoto, Toshihiro, Iwasaki, Hiromi, Kunisaki, Yuya, Akashi, Koichi
Publicado 2016

Arteriolar niches maintain haematopoietic stem cell quiescence

por Kunisaki, Yuya, Bruns, Ingmar, Scheiermann, Christoph, Ahmed, Jalal, Pinho, Sandra, Zhang, Dachuan, Mizoguchi, Toshihide, Wei, Qiaozhi, Lucas, Daniel, Ito, Keisuke, Mar, Jessica C., Bergman, Aviv, Frenette, Paul S.
Publicado 2013

Neutrophil ageing is regulated by the microbiome

por Zhang, Dachuan, Chen, Grace, Manwani, Deepa, Mortha, Arthur, Xu, Chunliang, Faith, Jeremiah J., Burk, Robert D., Kunisaki, Yuya, Jang, Jung-Eun, Scheiermann, Christoph, Merad, Miriam, Frenette, Paul S.
Publicado 2015

Human acute leukemia uses branched-chain amino acid catabolism to maintain stemness through regulating PRC2 function

por Kikushige, Yoshikane, Miyamoto, Toshihiro, Kochi, Yu, Semba, Yuichiro, Ohishi, Maki, Irifune, Hidetoshi, Hatakeyama, Kiwamu, Kunisaki, Yuya, Sugio, Takeshi, Sakoda, Teppei, Miyawaki, Kohta, Kato, Koji, Soga, Tomoyoshi, Akashi, Koichi
Publicado 2022

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis

por Kidoya, Hiroyasu, Muramatsu, Fumitaka, Shimamura, Teppei, Jia, Weizhen, Satoh, Takashi, Hayashi, Yumiko, Naito, Hisamichi, Kunisaki, Yuya, Arai, Fumio, Seki, Masahide, Suzuki, Yutaka, Osawa, Tsuyoshi, Akira, Shizuo, Takakura, Nobuyuki
Publicado 2019

Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45(–) TER119(–)Erythroid and Lymphoid Progenitors

por Gotoh, Kazuhito, Kunisaki, Yuya, Mizuguchi, Soichi, Setoyama, Daiki, Hosokawa, Kentaro, Yao, Hisayuki, Nakashima, Yuya, Yagi, Mikako, Uchiumi, Takeshi, Semba, Yuichiro, Nogami, Jumpei, Akashi, Koichi, Arai, Fumio, Kang, Dongchon
Publicado 2020

POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis

por Nakashima, Kentaro, Kunisaki, Yuya, Hosokawa, Kentaro, Gotoh, Kazuhito, Yao, Hisayuki, Yuta, Ryosuke, Semba, Yuichiro, Nogami, Jumpei, Kikushige, Yoshikane, Stumpf, Patrick S., MacArthur, Ben D., Kang, Dongchon, Akashi, Koichi, Ohga, Shouichi, Arai, Fumio
Publicado 2023

CD169(+) macrophages provide a niche promoting erythropoiesis under homeostasis, myeloablation and in JAK2V617F-induced polycythemia vera

por Chow, Andrew, Huggins, Matthew, Ahmed, Jalal, Hashimoto, Daigo, Lucas, Daniel, Kunisaki, Yuya, Pinho, Sandra, Leboeuf, Marylene, Noizat, Clara, van Rooijen, Nico, Tanaka, Masato, Zhao, Zhizhuang Joe, Bergman, Aviv, Merad, Miriam, Frenette, Paul S.
Publicado 2013

A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL

por Miyawaki, Kohta, Kato, Koji, Sugio, Takeshi, Sasaki, Kensuke, Miyoshi, Hiroaki, Semba, Yuichiro, Kikushige, Yoshikane, Mori, Yasuo, Kunisaki, Yuya, Iwasaki, Hiromi, Miyamoto, Toshihiro, Kuo, Frank C., Aster, Jon C., Ohshima, Koichi, Maeda, Takahiro, Akashi, Koichi
Publicado 2022

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation

por Hashimoto, Daigo, Chow, Andrew, Greter, Melanie, Saenger, Yvonne, Kwan, Wing-Hong, Leboeuf, Marylene, Ginhoux, Florent, Ochando, Jordi C., Kunisaki, Yuya, van Rooijen, Nico, Liu, Chen, Teshima, Takanori, Heeger, Peter S., Stanley, E. Richard, Frenette, Paul S., Merad, Miriam
Publicado 2011

Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing

por Stumpf, Patrick S., Du, Xin, Imanishi, Haruka, Kunisaki, Yuya, Semba, Yuichiro, Noble, Timothy, Smith, Rosanna C. G., Rose-Zerili, Matthew, West, Jonathan J., Oreffo, Richard O. C., Farrahi, Katayoun, Niranjan, Mahesan, Akashi, Koichi, Arai, Fumio, MacArthur, Ben D.
Publicado 2020

Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth

por Oshima, Tsuyoshi, Niwa, Yoshimi, Kuwata, Keiko, Srivastava, Ashutosh, Hyoda, Tomoko, Tsuchiya, Yoshiki, Kumagai, Megumi, Tsuyuguchi, Masato, Tamaru, Teruya, Sugiyama, Akiko, Ono, Natsuko, Zolboot, Norjin, Aikawa, Yoshiki, Oishi, Shunsuke, Nonami, Atsushi, Arai, Fumio, Hagihara, Shinya, Yamaguchi, Junichiro, Tama, Florence, Kunisaki, Yuya, Yagita, Kazuhiro, Ikeda, Masaaki, Kinoshita, Takayoshi, Kay, Steve A., Itami, Kenichiro, Hirota, Tsuyoshi
Publicado 2019