The cholesterol transporter NPC1 is essential for epigenetic regulation and maturation of oligodendrocyte lineage cells

por Kunkel, Thaddeus J., Townsend, Alice, Sullivan, Kyle A., Merlet, Jean, Schuchman, Edward H., Jacobson, Daniel A., Lieberman, Andrew P.
Publicado 2023

Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage

por Ilnytska, Olga, Lai, Kimberly, Gorshkov, Kirill, Schultz, Mark L., Tran, Bruce Nguyen, Jeziorek, Maciej, Kunkel, Thaddeus J., Azaria, Ruth D., McLoughlin, Hayley S., Waghalter, Miriam, Xu, Yang, Schlame, Michael, Altan-Bonnet, Nihal, Zheng, Wei, Lieberman, Andrew P., Dobrowolski, Radek, Storch, Judith
Publicado 2021

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases

por Schultz, Mark L., Fawaz, Maria V., Azaria, Ruth D., Hollon, Todd C., Liu, Elaine A., Kunkel, Thaddeus J., Halseth, Troy A., Krus, Kelsey L., Ming, Ran, Morin, Emily E., McLoughlin, Hayley S., Bushart, David D., Paulson, Henry L., Shakkottai, Vikram G., Orringer, Daniel A., Schwendeman, Anna S., Lieberman, Andrew P.
Publicado 2019