In silico and in vitro analysis of small molecules and natural compounds targeting the 3CL protease of feline infectious peritonitis virus

por Theerawatanasirikul, Sirin, Kuo, Chih Jung, Phetcharat, Nanthawan, Lekcharoensuk, Porntippa
Publicado 2020

Engineering a novel endopeptidase based on SARS 3CL(pro)

por Kuo, Chih-Jung, Shih, Yan-Ping, Kan, Daphne, Liang, Po-Huang
Publicado 2009

Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate()

por Kuo, Chih-Jung, Chi, Ya-Hui, Hsu, John T.-A, Liang, Po-Huang
Publicado 2004

Structural-based virtual screening and in vitro assays for small molecules inhibiting the feline coronavirus 3CL protease as a surrogate platform for coronaviruses

por Theerawatanasirikul, Sirin, Kuo, Chih Jung, Phecharat, Nanthawan, Chootip, Jullada, Lekcharoensuk, Chalermpol, Lekcharoensuk, Porntippa
Publicado 2020

Leptospira Immunoglobulin-Like Protein B Interacts with the 20th Exon of Human Tropoelastin Contributing to Leptospiral Adhesion to Human Lung Cells

por Hsieh, Ching-Lin, Tseng, Andrew, He, Hongxuan, Kuo, Chih-Jung, Wang, Xuannian, Chang, Yung-Fu
Publicado 2017

Natural Phytochemicals, Luteolin and Isoginkgetin, Inhibit 3C Protease and Infection of FMDV, In Silico and In Vitro

por Theerawatanasirikul, Sirin, Thangthamniyom, Nattarat, Kuo, Chih-Jung, Semkum, Ploypailin, Phecharat, Nantawan, Chankeeree, Penpitcha, Lekcharoensuk, Porntippa
Publicado 2021

Identification of non-covalent 3C-like protease inhibitors against severe acute respiratory syndrome coronavirus-2 via virtual screening of a Korean compound library

por Lee, Joo-Youn, Kuo, Chih-Jung, Shin, Jin Soo, Jung, Eunhye, Liang, Po-Huang, Jung, Young-Sik
Publicado 2021

High‐level expression of ARID1A predicts a favourable outcome in triple‐negative breast cancer patients receiving paclitaxel‐based chemotherapy

por Lin, Yuan‐Feng, Tseng, Ing‐Jy, Kuo, Chih‐Jung, Lin, Hui‐Yu, Chiu, I‐Jen, Chiu, Hui‐Wen
Publicado 2018

Individual and common inhibitors of coronavirus and picornavirus main proteases

por Kuo, Chih-Jung, Liu, Hun-Ge, Lo, Yueh-Kuei, Seong, Churl-Min, Lee, Kee-In, Jung, Young-Sik, Liang, Po-Huang
Publicado 2009

Corrigendum to “Individual and common inhibitors of coronavirus and picornavirus main proteases” [FEBS Lett. 583 (2009) 549–555]

por Kuo, Chih-Jung, Liu, Hun-Ge, Lo, Yueh-Kuei, Seong, Churl-Min, Lee, Kee-In, Jung, Young-Sik, Liang, Po-Huang
Publicado 2009

The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer

por Huang, Shang-Pen, Liu, Pei-Yao, Kuo, Chih-Jung, Chen, Chi-Long, Lee, Wei-Jiunn, Tsai, Yu-Hui, Lin, Yuan-Feng
Publicado 2017

Evaluation of a type 2 modified live porcine reproductive and respiratory syndrome vaccine against heterologous challenge of a lineage 3 highly virulent isolate in pigs

por Hou, Fu-Hsiang, Lee, Wei-Cheng, Liao, Jiunn-Wang, Chien, Maw-Sheng, Kuo, Chih-Jung, Chung, Han-Ping, Chia, Min-Yuan
Publicado 2020

Autochthonous Lactic Acid Bacteria Isolated From Dairy Cow Feces Exhibiting Promising Probiotic Properties and in vitro Antibacterial Activity Against Foodborne Pathogens in Cattle

por Lin, Wen-Chin, Ptak, Christopher P., Chang, Chi-Yu, Ian, Man-Kei, Chia, Min-Yuan, Chen, Ter-Hsin, Kuo, Chih-Jung
Publicado 2020

Structural basis of mercury‐ and zinc‐conjugated complexes as SARS‐CoV 3C‐like protease inhibitors

por Lee, Cheng-Chung, Kuo, Chih-Jung, Hsu, Min-Feng, Liang, Po-Huang, Fang, Jim-Min, Shie, Jiun-Jie, Wang, Andrew H.-J.
Publicado 2007

Structure-Based Inhibitors Exhibit Differential Activities against Helicobacter pylori and Escherichia coli Undecaprenyl Pyrophosphate Synthases

por Kuo, Chih-Jung, Guo, Rey-Ting, Lu, I-Lin, Liu, Hun-Ge, Wu, Su-Ying, Ko, Tzu-Ping, Wang, Andrew H.-J., Liang, Po-Huang
Publicado 2008

Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication

por Wen, Chih-Chun, Shyur, Lie-Fen, Jan, Jia-Tsrong, Liang, Po-Huang, Kuo, Chih-Jung, Arulselvan, Palanisamy, Wu, Jin-Bin, Kuo, Sheng-Chu, Yang, Ning-Sun
Publicado 2011

Isolation and Characterization of the Novel Phage JD032 and Global Transcriptomic Response during JD032 Infection of Clostridioides difficile Ribotype 078

por Li, Tinghua, Zhang, Yan, Dong, Ke, Kuo, Chih-Jung, Li, Chong, Zhu, Yong-Qiang, Qin, Jinhong, Li, Qing-Tian, Chang, Yung-Fu, Guo, Xiaokui, Zhu, Yongzhang
Publicado 2020

Evaluation of metal‐conjugated compounds as inhibitors of 3CL protease of SARS‐CoV

por Hsu, John T.-A., Kuo, Chih-Jung, Hsieh, Hsing-Pang, Wang, Yeau-Ching, Huang, Kuo-Kuei, Lin, Coney P.-C., Huang, Ping-Fang, Chen, Xin, Liang, Po-Huang
Publicado 2004

Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2

por Kuo, Chih-Jung, Chao, Tai-Ling, Kao, Han-Chieh, Tsai, Ya-Min, Liu, Yi-Kai, Wang, Lily Hui-Ching, Hsieh, Ming-Chang, Chang, Sui-Yuan, Liang, Po-Huang
Publicado 2021

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

por Wu, Chung-Yi, King, Ke-Yung, Kuo, Chih-Jung, Fang, Jim-Min, Wu, Ying-Ta, Ho, Ming-Yi, Liao, Chung-Lin, Shie, Jiun-Jie, Liang, Po-Huang, Wong, Chi-Huey
Publicado 2006