Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA

por Hormeno, Silvia, Wilkinson, Oliver J., Aicart-Ramos, Clara, Kuppa, Sahiti, Antony, Edwin, Dillingham, Mark S., Moreno-Herrero, Fernando
Publicado 2022

Interplay of macromolecular interactions during assembly of human DNA polymerase δ holoenzymes and initiation of DNA synthesis

por Norris, Jessica L., Rogers, Lindsey O., Pytko, Kara G., Dannenberg, Rachel L., Perreault, Samuel, Kaushik, Vikas, Kuppa, Sahiti, Antony, Edwin, Hedglin, Mark
Publicado 2023

Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability

por Graziano, Simona, Coll-Bonfill, Nuria, Teodoro-Castro, Barbara, Kuppa, Sahiti, Jackson, Jessica, Shashkova, Elena, Mahajan, Urvashi, Vindigni, Alessandro, Antony, Edwin, Gonzalo, Susana
Publicado 2021

An Aurora B-RPA signaling axis secures chromosome segregation fidelity

por Roshan, Poonam, Kuppa, Sahiti, Mattice, Jenna R., Kaushik, Vikas, Chadda, Rahul, Pokhrel, Nilisha, Tumala, Brunda R., Biswas, Aparna, Bothner, Brian, Antony, Edwin, Origanti, Sofia
Publicado 2023

Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit

por Elliff, Jonah, Biswas, Aparna, Roshan, Poonam, Kuppa, Sahiti, Patterson, Angela, Mattice, Jenna, Chinnaraj, Mathivanan, Burd, Ryan, Walker, Sarah E, Pozzi, Nicola, Antony, Edwin, Bothner, Brian, Origanti, Sofia
Publicado 2023

Rtt105 regulates RPA function by configurationally stapling the flexible domains

por Kuppa, Sahiti, Deveryshetty, Jaigeeth, Chadda, Rahul, Mattice, Jenna R., Pokhrel, Nilisha, Kaushik, Vikas, Patterson, Angela, Dhingra, Nalini, Pangeni, Sushil, Sadauskas, Marisa K., Shiekh, Sajad, Balci, Hamza, Ha, Taekjip, Zhao, Xiaolan, Bothner, Brian, Antony, Edwin
Publicado 2022