The Ryanodine Receptor as a Sensor for Intracellular Environments in Muscles

por Kobayashi, Takuya, Kurebayashi, Nagomi, Murayama, Takashi
Publicado 2021

Regulatory mechanisms of ryanodine receptor/Ca(2+) release channel revealed by recent advancements in structural studies

por Ogawa, Haruo, Kurebayashi, Nagomi, Yamazawa, Toshiko, Murayama, Takashi
Publicado 2020

Engineering a Novel Multifunctional Green Fluorescent Protein Tag for a Wide Variety of Protein Research

por Kobayashi, Takuya, Morone, Nobuhiro, Kashiyama, Taku, Oyamada, Hideto, Kurebayashi, Nagomi, Murayama, Takashi
Publicado 2008

Causes of Abnormal Ca(2+) Transients in Guinea Pig Pathophysiological Ventricular Muscle Revealed by Ca(2+) and Action Potential Imaging at Cellular Level

por Nishizawa, Hiroto, Suzuki, Takeshi, Shioya, Takao, Nakazato, Yuji, Daida, Hiroyuki, Kurebayashi, Nagomi
Publicado 2009

A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca(2+) sensitivity

por Murayama, Takashi, Ogawa, Haruo, Kurebayashi, Nagomi, Ohno, Seiko, Horie, Minoru, Sakurai, Takashi
Publicado 2018

Abnormal Features in Skeletal Muscle from Mice Lacking Mitsugumin29

por Nishi, Miyuki, Komazaki, Shinji, Kurebayashi, Nagomi, Ogawa, Yasuo, Noda, Tetsuo, Iino, Masamitsu, Takeshima, Hiroshi
Publicado 1999

Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM

por Iyer, Kavita A., Hu, Yifan, Nayak, Ashok R., Kurebayashi, Nagomi, Murayama, Takashi, Samsó, Montserrat
Publicado 2020

Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region

por Murayama, Takashi, Kurebayashi, Nagomi, Yamazawa, Toshiko, Oyamada, Hideto, Suzuki, Junji, Kanemaru, Kazunori, Oguchi, Katsuji, Iino, Masamitsu, Sakurai, Takashi
Publicado 2015

Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations

por Kobayashi, Takuya, Tsutsumi, Akihisa, Kurebayashi, Nagomi, Saito, Kei, Kodama, Masami, Sakurai, Takashi, Kikkawa, Masahide, Murayama, Takashi, Ogawa, Haruo
Publicado 2022

Involvement of kallikrein‐PAR2‐proinflammatory pathway in severe trastuzumab‐induced cardiotoxicity

por Sasaki, Ritsuko, Kurebayashi, Nagomi, Eguchi, Hidetaka, Horimoto, Yoshiya, Shiga, Takahiro, Miyazaki, Sakiko, Kashiyama, Taku, Akamatsu, Wado, Saito, Mitsue
Publicado 2022

In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca(2+) Transients via a Gap Junction Characteristic of Developing Cochlea

por Fukunaga, Ichiro, Fujimoto, Ayumi, Hatakeyama, Kaori, Aoki, Toru, Nishikawa, Atena, Noda, Tetsuo, Minowa, Osamu, Kurebayashi, Nagomi, Ikeda, Katsuhisa, Kamiya, Kazusaku
Publicado 2016

Inositol 1,4,5‐trisphosphate receptor determines intracellular Ca(2+) concentration in Trypanosoma cruzi throughout its life cycle

por Hashimoto, Muneaki, Doi, Motomichi, Kurebayashi, Nagomi, Furukawa, Koji, Hirawake‐Mogi, Hiroko, Ohmiya, Yoshihiro, Sakurai, Takashi, Mita, Toshihiro, Mikoshiba, Katsuhiko, Nara, Takeshi
Publicado 2016

Extensive Ca(2+) leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca(2+) hypersensitivity

por Uehara, Akira, Murayama, Takashi, Yasukochi, Midori, Fill, Michael, Horie, Minoru, Okamoto, Toru, Matsuura, Yoshiharu, Uehara, Kiyoko, Fujimoto, Takahiro, Sakurai, Takashi, Kurebayashi, Nagomi
Publicado 2017

Long‐term, but not short‐term high‐fat diet induces fiber composition changes and impaired contractile force in mouse fast‐twitch skeletal muscle

por Eshima, Hiroaki, Tamura, Yoshifumi, Kakehi, Saori, Kurebayashi, Nagomi, Murayama, Takashi, Nakamura, Kyoko, Kakigi, Ryo, Okada, Takao, Sakurai, Takashi, Kawamori, Ryuzo, Watada, Hirotaka
Publicado 2017

Insights into channel modulation mechanism of RYR1 mutants using Ca(2+) imaging and molecular dynamics

por Yamazawa, Toshiko, Ogawa, Haruo, Murayama, Takashi, Yamaguchi, Maki, Oyamada, Hideto, Suzuki, Junji, Kurebayashi, Nagomi, Kanemaru, Kazunori, Oguchi, Katsuji, Sakurai, Takashi, Iino, Masamitsu
Publicado 2019

Cytosolic Ca(2+)-dependent Ca(2+) release activity primarily determines the ER Ca(2+) level in cells expressing the CPVT-linked mutant RYR2

por Kurebayashi, Nagomi, Murayama, Takashi, Ota, Ryosaku, Suzuki, Junji, Kanemaru, Kazunori, Kobayashi, Takuya, Ohno, Seiko, Horie, Minoru, Iino, Masamitsu, Yamashita, Fumiyoshi, Sakurai, Takashi
Publicado 2022

Usefulness of Running Wheel for Detection of Congestive Heart Failure in Dilated Cardiomyopathy Mouse Model

por Sugihara, Masami, Odagiri, Fuminori, Suzuki, Takeshi, Murayama, Takashi, Nakazato, Yuji, Unuma, Kana, Yoshida, Ken-ichi, Daida, Hiroyuki, Sakurai, Takashi, Morimoto, Sachio, Kurebayashi, Nagomi
Publicado 2013

Multistep Ion Channel Remodeling and Lethal Arrhythmia Precede Heart Failure in a Mouse Model of Inherited Dilated Cardiomyopathy

por Suzuki, Takeshi, Shioya, Takao, Murayama, Takashi, Sugihara, Masami, Odagiri, Fuminori, Nakazato, Yuji, Nishizawa, Hiroto, Chugun, Akihito, Sakurai, Takashi, Daida, Hiroyuki, Morimoto, Sachio, Kurebayashi, Nagomi
Publicado 2012

Effects of Candesartan on Electrical Remodeling in the Hearts of Inherited Dilated Cardiomyopathy Model Mice

por Odagiri, Fuminori, Inoue, Hana, Sugihara, Masami, Suzuki, Takeshi, Murayama, Takashi, Shioya, Takao, Konishi, Masato, Nakazato, Yuji, Daida, Hiroyuki, Sakurai, Takashi, Morimoto, Sachio, Kurebayashi, Nagomi
Publicado 2014

A reconstituted depolarization-induced Ca(2+) release platform for validation of skeletal muscle disease mutations and drug discovery

por Murayama, Takashi, Kurebayashi, Nagomi, Numaga-Tomita, Takuro, Kobayashi, Takuya, Okazaki, Satoru, Yamashiro, Kyosuke, Nakada, Tsutomu, Mori, Shuichi, Ishida, Ryosuke, Kagechika, Hiroyuki, Yamada, Mitsuhiko, Sakurai, Takashi
Publicado 2022